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T16769Ro 363;化合物 T16769Ro 363
RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is an effective and highly selective β1-adrenoceptor agonist.
价 格:¥电议型 号:T16769产 地:中国大陆
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T16768Ro-24-4736;化合物 T16768Ro-24-4736
Ro 24-4736 is an effective and selective platelet-activating factor antagonist.
价 格:¥电议型 号:T16768产 地:中国大陆
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T16736Retosiban;化合物 T16736GSK 221149|||GSK 221149A;GSK 221149|||GSK 221149A
Retosiban is an effective and selective oxytocin antagonist (Ki: 0.65 nM).
价 格:¥电议型 号:T16736产 地:中国大陆
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T16636Propargyl-PEG5-amine;化合物 T16636Propargyl-PEG5-amine
Propargyl-PEG5-amine is a non-cleavable linker compound, employed in the synthesis of antibody-drug conjugates (ADCs) and PROTACs. It is PEG-based and serves as a connector in the formation of ADCs and PROTACs[1].
价 格:¥电议型 号:T16636产 地:中国大陆
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T16573Pratosartan;化合物 T16573KT 3671|||FW 7203|||KD 3-671;KT 3671|||FW 7203|||KD 3-671
Pratosartan is a selective antagonist of angiotensin II receptor.
价 格:¥电议型 号:T16573产 地:中国大陆
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T16544Pivalopril;化合物 T16544Pivopril|||RHC 3659(S);Pivopril|||RHC 3659(S)
Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
价 格:¥电议型 号:T16544产 地:中国大陆
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T16536Pimonidazole hydrochloride;化合物Pimonidazole hydrochloridePimonidazole hydrochloride
Pimonidazole hydrochloride accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole hydrochloride is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.
价 格:¥电议型 号:T16536产 地:中国大陆
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T16512PFE-360;化合物PFE-360PF-06685360;PF-06685360
PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).
价 格:¥电议型 号:T16512产 地:中国大陆
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T16504PF-4693627;化合物 T16504PF-4693627
PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM). It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA).
价 格:¥电议型 号:T16504产 地:中国大陆
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T16501PF-3644022;化合物PF-3644022PF-3644022
PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) (IC50s: 53 nM and 5.0 nM, respectively).
价 格:¥电议型 号:T16501产 地:中国大陆
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T16476PF-03654746;化合物PF-03654746PF-03654746
PF-03654746 is a selective antagonist of the histamine H3 receptor. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer´s disease. PF-03654746 can be used in studies about the treatment of allergic rhinitis.
价 格:¥电议型 号:T16476产 地:中国大陆
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T16436PBOX 6;化合物PBOX 6PBOX-6;PBOX-6
PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits breast cancer cell growth in vitro and selectively induces apoptosis in leukemia cells via c-Jun NH2 terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL.
价 格:¥电议型 号:T16436产 地:中国大陆
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T16423p32 Inhibitor M36化合物 T16423M36
p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
价 格:¥电议型 号:T16423产 地:中国大陆
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T16396OP-3633;化合物 T16396OP-3633
OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM). OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.
价 格:¥电议型 号:T16396产 地:中国大陆
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T1639Amlexanox;氨来呫诺CHX3673|||Amoxanox|||AA673;氨来呫诺|||CHX3673|||Amoxanox|||氨来诺|||AA673
Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers.
价 格:¥电议型 号:T1639产 地:中国大陆
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T1636LParoxetine hydrochloride hemihydrate;盐酸帕罗西汀半水合物Paroxetine Hydrochloride|||Paxil|||Paroxetine HCl|||S
Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).
价 格:¥电议型 号:T1636L产 地:中国大陆
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T16369O-Desmethyl gefitinib;O-去甲基吉非替尼O-Desmethyl gefitinib
O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 activity.
价 格:¥电议型 号:T16369产 地:中国大陆
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T16368NVX-207;化合物 T16368NVX-207
NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.
价 格:¥电议型 号:T16368产 地:中国大陆
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T16367NVS-PAK1-1;化合物NVS-PAK1-1NVS-PAK1-1
NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).
价 格:¥电议型 号:T16367产 地:中国大陆
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T16366NVR 3-778;化合物NVR 3-778NVR 3-778
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.
价 格:¥电议型 号:T16366产 地:中国大陆