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T16365Buparlisib Hydrochloride化合物 T16365NVP-BKM120 Hydrochloride|||BKM120 Hydrochloride
Buparlisib Hydrochloride is an inhibitor of pan-class I PI3K (IC50: 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively).
价 格:¥电议型 号:T16365产 地:中国大陆
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T16364Infigratinib phosphate;磷酸英非替尼NVP-BGJ398 phosphate|||BGJ-398 phosphate;NVP-BGJ398 phosphate|||BGJ-398
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
价 格:¥电议型 号:T16364产 地:中国大陆
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T16363NVP-2;化合物NVP-2NVP-2
NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 μM, 0.706 μM, and 0.605 μM, respectively).
价 格:¥电议型 号:T16363产 地:中国大陆
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T16362Nuvenzepine;化合物 T16362Nuvenzepine
Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.
价 格:¥电议型 号:T16362产 地:中国大陆
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T16360NU6300;化合物 T16360NU6300
NU6300 is an inhibitor of the first covalent ATP-competitive CDK2.
价 格:¥电议型 号:T16360产 地:中国大陆
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T1636Paroxetine hydrochloride;盐酸帕罗西汀Paroxetine HCl|||BRL29060 hydrochloride|||FG-7051|||BRL29060A;Paroxet
Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.
价 格:¥电议型 号:T1636产 地:中国大陆
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T16347NS3623;化合物NS3623NS3623
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic effect.
价 格:¥电议型 号:T16347产 地:中国大陆
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T16336Nonaethylene glycol monomethyl ether;化合物 T16336Nonaethylene glycol monomethyl ether
Nonaethylene glycol monomethyl ether, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].
价 格:¥电议型 号:T16336产 地:中国大陆
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T16275NB001;化合物NB001HTS 09836;HTS 09836
NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.
价 格:¥电议型 号:T16275产 地:中国大陆
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T16236N-Me-N-bis(PEG2-propargyl);化合物 T16236N-Me-N-bis(PEG2-propargyl)
N-Me-N-bis(PEG2-propargyl) is a PEG-based linker employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T16236产 地:中国大陆
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T1615Irbesartan;厄贝沙坦SR-47436|||BMS-186295;厄贝沙坦|||SR-47436|||BMS-186295
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
价 格:¥电议型 号:T1615产 地:中国大陆
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T16141MRT00033659;化合物 T16141MRT00033659
MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 μM for CK1δ) and CHK1 (IC50=0.23 μM). MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.
价 格:¥电议型 号:T16141产 地:中国大陆
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T16136MRS-1706;化合物MRS-1706MRS-1706
MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1, and A3 receptors respectively. MRS-1706 is an effective and selective adenosine A2B receptor inverse agonist.
价 格:¥电议型 号:T16136产 地:中国大陆
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T16109ML402;化合物ML402ZINC3671497|||N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide;ZINC3671497
ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
价 格:¥电议型 号:T16109产 地:中国大陆
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T16106ML224;化合物ML224NCGC00242364|||ANTAG3;NCGC00242364|||ANTAG3
ML224 (NCGC00242364) is a TSHR antagonist for the treatment of Graves´ orbital disease and Graves´ hyperthyroidism.
价 格:¥电议型 号:T16106产 地:中国大陆
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T16036Melinamide;甲亚油酰胺AC 223|||DL-N-(α-Methylbenzyl)linoleamide;甲亚油酰胺|||AC 223|||DL-N-(α-Methylbenzyl)lino
Melinamide is an amide derivative of an unsaturated long-chain fatty acid and also is an inhibitor of cholesterol absorption (IC50: 20.9 μM).
价 格:¥电议型 号:T16036产 地:中国大陆
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T15936m-PEG8-NHS ester;化合物 T15936m-PEG8-NHS ester
m-PEG8-NHS ester is a non-cleavable 8 unit polyethylene glycol (PEG) linker compound, employed in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T15936产 地:中国大陆
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T15836m-PEG10-azide;化合物 T15836m-PEG10-azide
m-PEG10-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15836产 地:中国大陆
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T1582LNaproxen sodium;萘普生钠Miranax|||Anaprox|||RS-3650|||Naprelan;Miranax|||Anaprox|||RS-3650|||Naprelan|||
Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.
价 格:¥电议型 号:T1582L产 地:中国大陆
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T15818LY367385;化合物 T15818LY367385
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis.
价 格:¥电议型 号:T15818产 地:中国大陆