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T11654Indirubin Derivative E804；化合物 T11654Indirubin Derivative E804
Indirubin Derivative E804 is an effective inhibitor of IGF1R, which has an IC50 value of 0.65.
价 格：￥电议型 号：T11654产 地：中国大陆
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T11653Indirubin-5-sulfonate；化合物 T11653Indirubin-5-sulfonate
Indirubin-5-sulfonate shows inhibitory activity against GSK-3β. Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively.
价 格：￥电议型 号：T11653产 地：中国大陆
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T11651Indanidine；吲达尼定Indanidine
Indanidine is a highly selective and potent α-adrenergic agonist with antihypertensive activity.Indanidine is an α-adrenergic antagonist that can be used in the study of neurological disorders.
价 格：￥电议型 号：T11651产 地：中国大陆
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T11650INCB3344 R-isomer；化合物 T11650INCB3344 R-isomer
INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.
价 格：￥电议型 号：T11650产 地：中国大陆
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T1165Ethionamide乙硫异烟胺Bayer 5312|||乙硫异烟胺|||2-ethylthioisonicotinamide|||Ethinamide
Ethionamide (2-ethylthioisonicotinamide) is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the con
价 格：￥电议型 号：T1165产 地：中国大陆
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T11606ICA-105665；化合物 T11606PF-04895162；PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格：￥电议型 号：T11606产 地：中国大陆
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T11601Ibrutinib-d5；化合物 T11601PCI-32765 D5|||Ibrutinib D5；PCI-32765 D5|||Ibrutinib D5
Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.
价 格：￥电议型 号：T11601产 地：中国大陆
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T11565HIV-1 integrase inhibitor 7；化合物 T11565HIV-1 integrase inhibitor 7
HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).
价 格：￥电议型 号：T11565产 地：中国大陆
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T11530LH3B-6545；化合物 T11530LH3B-6545
H3B-6545 is an oral and selective antagonist of estrogen receptor covalent (SERCA).
价 格：￥电议型 号：T11530L产 地：中国大陆
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T11530H3B-6545 Hydrochloride；化合物 T11530H3B-6545 Hydrochloride
H3B-6545 Hydrochloride is a selective, oral estrogen receptor covalent antagonist (SERCA).
价 格：￥电议型 号：T11530产 地：中国大陆
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T1153Trimethoprim；甲氧苄啶NIH 204|||BW 56-72|||NSC-106568；NIH 204|||BW 56-72|||甲氧苄啶|||NSC-106568
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
价 格：￥电议型 号：T1153产 地：中国大陆
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T1151Roxithromycin；罗红霉素Roxl-150|||RU-28965；Roxl-150|||罗红霉素|||RU-28965
Roxithromycin (RU-28965) is a semi-synthetic derivative of the macrolide antibiotic erythromycin with antibacterial and anti-malarial activities.
价 格：￥电议型 号：T1151产 地：中国大陆
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T11497Ganfeborole HCl；Ganfeborole 盐酸盐GSK3036656 HCl|||GSK656 HCl；GSK3036656 HCl|||GSK656 HCl
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM).
价 格：￥电议型 号：T11497产 地：中国大陆
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T11477GSK1059865；化合物 T11477GSK1059865
GSK1059865 is a potent antagonist of the orexin 1 receptor.
价 格：￥电议型 号：T11477产 地：中国大陆
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T11465Lenacapavir；化合物LenacapavirGS-6207；GS-6207
Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
价 格：￥电议型 号：T11465产 地：中国大陆
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T11365Ganodermanontriol；灵芝马酮Ganodermanontriol
Ganodermanontriol, a sterol derived from Ganoderma lucidum, showcases hepatoprotective activity and possesses anti-inflammatory properties in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the upregulation of HO-1 expression.
价 格：￥电议型 号：T11365产 地：中国大陆
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T11327LFR 167653 free base；化合物 T11327LFR 167653 free base
FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.
价 格：￥电议型 号：T11327L产 地：中国大陆
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T11277FG 7142；化合物FG 7142ZK 39106|||LSU-65；ZK 39106|||LSU-65
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).
价 格：￥电议型 号：T11277产 地：中国大陆
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T11265Faropenem daloxate；法罗培南酯Faropenem medoxil；法罗培南酯|||Faropenem medoxil
Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics. Faropenem medoxomil has excellent in vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and other key pathogens implicated in acute bacterial rhinosinusitis.Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.
价 格：￥电议型 号：T11265产 地：中国大陆
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T11247Etravirine D4；依曲韦林 D4R-165335 D4|||TMC-125 D4；R-165335 D4|||TMC-125 D4|||依曲韦林 D4
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
价 格：￥电议型 号：T11247产 地：中国大陆
