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T1544Olsalazine disodium；奥沙拉秦钠Dipentum|||Olsalazine Sodium；Dipentum|||奥沙拉秦钠|||Olsalazine Sodium
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
价 格：￥电议型 号：T1544产 地：中国大陆
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T15439GSK3395879；化合物 T15439GSK3395879
GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).
价 格：￥电议型 号：T15439产 地：中国大陆
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T15438GSK3186899；化合物GSK31868993,3,3-trifluoro-N-[4-[[3-[(2R)-2-methylmorpholin-4-yl]-1H-pyrazolo[3,4-d]pyr
GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.
价 格：￥电议型 号：T15438产 地：中国大陆
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T15437GSK3145095；化合物GSK3145095GSK3145095
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.
价 格：￥电议型 号：T15437产 地：中国大陆
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T15436GSK2838232；化合物GSK2838232GSK2838232
GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.
价 格：￥电议型 号：T15436产 地：中国大陆
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T15435GSK2837808A；化合物GSK2837808AGSK2837808A
GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).
价 格：￥电议型 号：T15435产 地：中国大陆
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T15434GSK2798745；化合物 T15434GSK2798745
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in research for the treatment of pulmonary edema associated with congestive heart failure.
价 格：￥电议型 号：T15434产 地：中国大陆
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T15433GSK2795039；化合物GSK2795039GSK2795039
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).
价 格：￥电议型 号：T15433产 地：中国大陆
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T15432GSK256073；化合物GSK256073GSK256073
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis.
价 格：￥电议型 号：T15432产 地：中国大陆
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T15431Nemiralisib；奈米利塞GSK2269557 (free base)|||GSK2269557；GSK2269557 (free base)|||GSK2269557
Nemiralisib（GSK-2269557 free base） is an orally available, potent and specific PI3Kδ inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disease.
价 格：￥电议型 号：T15431产 地：中国大陆
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T15430GSK2256294A；化合物GSK2256294AGSK 2256294；GSK 2256294
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.
价 格：￥电议型 号：T15430产 地：中国大陆
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T1543Naftifine hydrochloride；盐酸萘替芬Naftifungin|||Naftifine HCl|||Naftin|||Exoderil；Naftifungin|||盐酸萘替芬|||N
Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulat
价 格：￥电议型 号：T1543产 地：中国大陆
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T15429GSK2194069；化合物GSK2194069GSK2194069
GSK2194069 is an active β-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH.
价 格：￥电议型 号：T15429产 地：中国大陆
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T15428Uprosertib hydrochloride；化合物 T15428GSK2141795 (hydrochloride)；GSK2141795 (hydrochloride)
Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).
价 格：￥电议型 号：T15428产 地：中国大陆
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T15427GSK2033；化合物GSK2033GSK2033
GSK2033 is an antagonist of LXR (pIC50s: 7 and 7.4 for LXRα or LXRβ, respectively).
价 格：￥电议型 号：T15427产 地：中国大陆
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T15426GSK180；化合物 T15426GSK180
GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.
价 格：￥电议型 号：T15426产 地：中国大陆
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T15425GSK1702934A；化合物 T15425GSK1702934A
GSK1702934A is a selective TRPC3 agonist. It modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3.
价 格：￥电议型 号：T15425产 地：中国大陆
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T15424GSK1379725A；化合物GSK1379725AGSK1379725A
GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
价 格：￥电议型 号：T15424产 地：中国大陆
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T15422GSK-626616；化合物GSK-626616GSK-626616
GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia.
价 格：￥电议型 号：T15422产 地：中国大陆
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T15421GSK-269984A；化合物 T15421GSK-269984A
GSK-269984A is an antagonist of Prostaglandin E2 Receptor 1 (EP1) (pIC50: 7.9).
价 格：￥电议型 号：T15421产 地：中国大陆
