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T31221LdBRD9 HCl
dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl does not degrade BRD4 or BRD7 at concentrations up to 5 μM. dBRD9 HCl displays antiproliferative effects in human AML cell lines.
价 格:¥电议型 号:T31221L产 地:中国大陆
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TJS2190Nordihydroguaiaretic acidInhibitor,LOX,Nordihydroguaiaretic acid,inhibit,Lipoxygenase,Ferroptosis,Au
Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties.
价 格:¥电议型 号:TJS2190产 地:中国大陆
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T21852AEG 3482AEG 3482
AEG 3482 is a potent antiapoptotic compound. AEG 3482 inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG 3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25.
价 格:¥电议型 号:T21852产 地:中国大陆
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TMS2181trans-Zeatininhibit,trans Zeatin,ERK,Endogenous Metabolite,Mitogen-activated protein kinase kinase,M
Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
价 格:¥电议型 号:TMS2181产 地:中国大陆
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T6324BIX02188334949-59-6
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.
价 格:¥电议型 号:T6324产 地:中国大陆
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T6321TofacitinibTasocitinib;CP-690550;托法替尼
Tofacitinib is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis.
价 格:¥电议型 号:T6321产 地:中国大陆
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T6316CalcitriolCalcijex;1,25-Dihydroxyvitamin D3;Topitriol;RO215535;Rocaltrol;骨化三醇
Calcitriol is the physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calci
价 格:¥电议型 号:T6316产 地:中国大陆
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T6307Lubiprostone芦比前列酮;鲁比前列酮;RU-0211;SPI-0211
Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.
价 格:¥电议型 号:T6307产 地:中国大陆
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T6305SNX2112SNX 2112;PF 04928473;SNX-2112
SNX-2112 is an orally active Hsp90 inhibitor, with a Kd of 16 nM.
价 格:¥电议型 号:T6305产 地:中国大陆
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T6256YYA-021YYA 021;YYA021
YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
价 格:¥电议型 号:T6256产 地:中国大陆
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T6231Tebipenem Pivoxil替?比?培?南?匹?酯;ME1211;Orapenem
Tebipenem pivoxil, an orally activity carbapenem antibiotic, is utilized in treating otolaryngologic and respiratory infections.
价 格:¥电议型 号:T6231产 地:中国大陆
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T6221Nalmefene hydrochlorideNalmefene HCl
Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS.
价 格:¥电议型 号:T6221产 地:中国大陆
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T6219Azilsartan Medoxomil阿齐沙坦酯;TAK-491
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
价 格:¥电议型 号:T6219产 地:中国大陆
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T6218SelumetinibARRY-142886;AZD6244;司美替尼
Selumetinib (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).
价 格:¥电议型 号:T6218产 地:中国大陆
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T6217LFM-A13
LFM-A13(IC50=2.5 μM), a specific Bruton´s tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.
价 格:¥电议型 号:T6217产 地:中国大陆
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T6216Abiraterone阿比特龙;CB-7598
Abiraterone (CB-7598) is an effective steroidal cytochrome P450 17alpha-hydroxylase-17, 20-lyase (CYP17) inhibitor (IC50: 4 nM).
价 格:¥电议型 号:T6216产 地:中国大陆
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T6215Abiraterone Acetate乙酸阿比特龙酯;CB7630;Zytiga
Abiraterone acetate is an androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.
价 格:¥电议型 号:T6215产 地:中国大陆
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T6214Emtricitabine恩曲他滨;Emtriva;FTC;BW1592
Emtricitabine (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.
价 格:¥电议型 号:T6214产 地:中国大陆
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T6211PosaconazoleSCH 56592;POS;泊沙康唑
Posaconazole is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).
价 格:¥电议型 号:T6211产 地:中国大陆
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T6210Pifithrin-μPFTμ;2-Phenylethynesulfonamide;NSC 303580
Pifithrin-μ is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
价 格:¥电议型 号:T6210产 地:中国大陆