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T3504AZD5153 6-Hydroxy-2-naphthoic acidAZD5153;AZD-5153 HNT salt;AZD5153结晶体(API形式)
AZD5153 (6- Hydroxy- 2- naphthoic Acid) is a potent triazolopyridazine-based Bromodomain (BRD4) and Extraterminal (BET) inhibitor used in cancer treatments.
价 格:¥电议型 号:T3504产 地:中国大陆
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T3451JNJ-42153605JNJ42153605;JNJ 42153605
JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).
价 格:¥电议型 号:T3451产 地:中国大陆
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T33519MTOBKMBA;MTOB salt;α-keto-γ-Methylthiobutyric acid;4-methylthio 2-oxobutyric acid;4-甲硫基-2-氧丁酸钠
MTOB is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, leading to cancer stem cell (CSC) growth and self-renewal.
价 格:¥电议型 号:T33519产 地:中国大陆
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T33514MSC 2032964AMSC-2032964A;MSC2032964A
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
价 格:¥电议型 号:T33514产 地:中国大陆
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T3351OnatasertibCC-223;CC 223;CC223
CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. CC-223 is a potent mTOR kinase inhi
价 格:¥电议型 号:T3351产 地:中国大陆
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T3251Stachydrine Hydrochloride
Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.
价 格:¥电议型 号:T3251产 地:中国大陆
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T3211MidostaurinCGP 41251;CGP41231;PKC412;N-Benzoylstaurosporine;米哚妥林;苯甲酰基十字孢碱
PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) an
价 格:¥电议型 号:T3211产 地:中国大陆
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T3199PTACHNCH-51;Cpd 51
PTACH (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).
价 格:¥电议型 号:T3199产 地:中国大陆
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T3151Brassinolide芸苔素内酯;油菜;油菜素内酯;24-Epibrassinolide;Brassin lactone
Brassinolide is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.
价 格:¥电议型 号:T3151产 地:中国大陆
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T30751Carotegrast methylAJM300
Carotegrast methyl, an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.
价 格:¥电议型 号:T30751产 地:中国大陆
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T3053CZC-25146CZC25146;CZC 25146;CHEMBL2397014
CZC-25146 is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
价 格:¥电议型 号:T3053产 地:中国大陆
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T3051Theaflavin-3-gallateTheaflavine-3-Gallate;茶黄素-3-没食子酸酯;茶黄素 3-没食子酸酯;茶黄素 -3-没食子酸
Theaflavin-3-gallate can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell lung carcinoma, it acts as prooxidants and induce oxidativ
价 格:¥电议型 号:T3051产 地:中国大陆
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T29842AlclofenacBRN 2116510;W7320;W 7320;MY 101;W-7320
Alclofenac has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.
价 格:¥电议型 号:T29842产 地:中国大陆
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T2951β-Cyclodextrinβ-环糊精;beta-环糊精;NSC 269471;Betadex;Cyclomaltoheptaose;Beta-Cyclodextrin
Beta-Cyclodextrin is a member of the class of compounds known as oligosaccharides.
价 格:¥电议型 号:T2951产 地:中国大陆
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T2851Daphnetin瑞香素;7,8-Dihydroxycoumarin;Daphnetol
Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.
价 格:¥电议型 号:T2851产 地:中国大陆
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T28073MLS1547MLS 1547;MLS000051547;MLS-1547
MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist, which does not recruit β-arrestin.
价 格:¥电议型 号:T28073产 地:中国大陆
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T2753AvasimibePD-148515;CI-1011;阿伐麦布
Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 μM).
价 格:¥电议型 号:T2753产 地:中国大陆
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T2751Ginkgolide BBN-52021;银杏内酯B
Ginkgolide B is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.
价 格:¥电议型 号:T2751产 地:中国大陆
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T26519Ablukast阿鲁司特;Ro 23-3544
Ablukast is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.
价 格:¥电议型 号:T26519产 地:中国大陆
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T2651IWR-1IWR-1-endo;endo-IWR 1
IWR-1, a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
价 格:¥电议型 号:T2651产 地:中国大陆