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T3624A-366A 366;A366
Potent and selective G9a/GLP histone lysine methyltransferase inhibitor (IC50 = 3.3 nM). Exhibits >1000-fold selectivity for G9a/GLP over 21 other methyltransferases. Decreases levels of lysine 9 dimethylation on histone H3 (H3K9Me2) in PC3 cells.
价 格:¥电议型 号:T3624产 地:中国大陆
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T3623CobimetinibGDC-0973;RG7420;XL518;可美替尼;考比替尼
Cobimetinib is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of extracellular signal-related kinase 2 (ERK2) ph
价 格:¥电议型 号:T3623产 地:中国大陆
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T3622CP-640186 hydrochlorideCP 640186 HCl;盐酸CP-640186
CP-640186 HCl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stability than CP-610431.
价 格:¥电议型 号:T3622产 地:中国大陆
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T3621BrigatinibAP-26113;布格替尼
Brigatinib is a highly potent and selective ALK inhibitor.
价 格:¥电议型 号:T3621产 地:中国大陆
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T3620SolcitinibGSK-2586184;GLPG-0778;索西替尼
Solcitinib (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.
价 格:¥电议型 号:T3620产 地:中国大陆
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T35862Cucurbit[8]uril
Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy trans
价 格:¥电议型 号:T35862产 地:中国大陆
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T3562ValrocemideTV1901;N-Valproylglycinamide;N-丙戊酰基甘氨酰胺;丙戊塞胺
Valrocemide, also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is an anticonvulsant agent under development by Teva and Acorda as a potentia
价 格:¥电议型 号:T3562产 地:中国大陆
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T3554RG14620Tyrphostin RG14620;RG 14620
RG14620 is an epidermal growth factor receptor (EGFR) inhibitor.
价 格:¥电议型 号:T3554产 地:中国大陆
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T35362NSC622608
NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.
价 格:¥电议型 号:T35362产 地:中国大陆
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T3518GSK269962AGSK 269962;GSK269962B;GSK269962A HCl
GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
价 格:¥电议型 号:T3518产 地:中国大陆
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T3495TasimelteonVEC-162;BMS-214778;他司美琼
Tasimelteon is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.
价 格:¥电议型 号:T3495产 地:中国大陆
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T3462BMS-582949 hydrochlorideBMS-582949 HCl
The BMS-582949 hydrochloride is a highly specific p38α MAPK inhibitor (IC50: 13 nM).
价 格:¥电议型 号:T3462产 地:中国大陆
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T33762Fosifloxuridine nafalbenamideNUC-3373;NUC 3373;NUC3373
NUC-3373 (Fosifloxuridine nafalbenamide), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients
价 格:¥电议型 号:T33762产 地:中国大陆
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T3362EupatilinNSC 122413;异泽兰黄素
Eupatilin, a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.
价 格:¥电议型 号:T3362产 地:中国大陆
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T3283CetilistatATL-962;新利司他
Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
价 格:¥电议型 号:T3283产 地:中国大陆
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T3262Phosphocreatine disodium磷酸肌酸钠;Creatine phosphate disodium salt;Phosphocreatine disodium salt;Disodiu
Creatine phosphate is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain.
价 格:¥电议型 号:T3262产 地:中国大陆
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T3162IDE1
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-β
价 格:¥电议型 号:T3162产 地:中国大陆
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T30798CerlapirdineSAM-531;PF05212365;P -05212365;SAM531;SAM 531;WAY-262,531;PF-05212365
Cerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer´s disease and schizophrenia. It works by acti
价 格:¥电议型 号:T30798产 地:中国大陆
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T3073PF-670462PF670462
PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.
价 格:¥电议型 号:T3073产 地:中国大陆
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T3062WIKI4
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).
价 格:¥电议型 号:T3062产 地:中国大陆