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T2610BMS-599626;化合物BMS 599626AC480;AC480
BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.
价 格:¥电议型 号:T2610产 地:中国大陆
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T2586Cabozantinib卡博替尼卡博替尼|||XL184|||BMS-907351
Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity.
价 格:¥电议型 号:T2586产 地:中国大陆
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T2576Brivanib (alaninate);丙氨酸布立尼布BMS-582664|||Brivanib Alaninate;丙氨酸布立尼布|||BMS-582664|||Brivanib Alaninat
Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.
价 格:¥电议型 号:T2576产 地:中国大陆
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T2545Lomitapide Mesylate甲磺酸洛美他派甲磺酸洛美他派|||BMS-201038 mesylate|||AEGR-733 mesylate
Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
价 格:¥电议型 号:T2545产 地:中国大陆
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T25166BMS-663749 lysine;化合物 T25166BMS-663749 lysine salt|||BMS663749 lysine|||BMS 663749 lysine;BMS-663749
BMS-663749 lysine is used as a phosphonooxymethyl prodrug 4 for HIV-1 attachment inhibitor.
价 格:¥电议型 号:T25166产 地:中国大陆
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T25165LBMS-189664 HCl;化合物 T25165LBMS 189664 HCl|||BMS189664 HCl|||BMS-189664 hydrochloride;BMS 189664 HCl||
BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.
价 格:¥电议型 号:T25165L产 地:中国大陆
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T25165BMS-189664;化合物 T25165BMS-189664
BMS-189664 is an inhibitor of thrombin.
价 格:¥电议型 号:T25165产 地:中国大陆
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T25164BMS 180742;化合物 T25164BMS-180742|||BMS180742;BMS-180742|||BMS180742
BMS 180742 is an exosite inhibitor of thrombin.
价 格:¥电议型 号:T25164产 地:中国大陆
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T2419BMS-794833;化合物BMS794833BMS-794833
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
价 格:¥电议型 号:T2419产 地:中国大陆
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T2389Dapagliflozin;达格列净BMS-512148;达格列净|||BMS-512148
Dapagliflozin (BMS-512148) is a glucose co-transporter protein 2 (SGLT2) inhibitor that competitively binds to its target. Dapagliflozin is used in the treatment of type 2 diabetes mellitus and decreases glucose reabsorption in the kidneys and increases urinary excretion of glucose, which results in lowering plasma glucose levels.
价 格:¥电议型 号:T2389产 地:中国大陆
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T23808BMS-986169;化合物 T23808BMS-986169
BMS-986169 is a GluN2B Receptor Negative Allosteric Modulator. BMS-986169 showed a high binding affinity for the GluN2B subunit allosteric modulatory site (Ki: 4.03-6.3 nM) and selectively inhibited GluN2B receptor function in Xenopus oocytes expressing human N-methyl-d-aspartate receptor subtypes (IC50: 24.1 nM).
价 格:¥电议型 号:T23808产 地:中国大陆
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T23807BMS-955176 TFA;化合物 T23807BMS 955176|||GSK-3532795|||BMS955176|||BMS-955176|||GSK3532795;BMS 955176||
GSK3532795 is an orally active inhibitor of HIV-1 maturation. GSK3532795 combines broad coverage of polymorphic viruses (EC50: 15 nM toward a panel of common polymorphisms representative of 96.5% HIV-1 subtype B virus) with a favorable pharmacokinetic profile in preclinical species.
价 格:¥电议型 号:T23807产 地:中国大陆
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T23806BMS-466442;化合物 T23806BMS-466442
BMS-466442 is the first selective amino acid transporter alanine serine cysteine transporter-1 inhibitor.
价 格:¥电议型 号:T23806产 地:中国大陆
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T23805BMS-242;化合物 T23805BMS242;BMS242
BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.
价 格:¥电议型 号:T23805产 地:中国大陆
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T2349BMS-754807;化合物BMS-754807BMS-754807
Dual IGF-1R/InsR Inhibitor BMS-754807 is an oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases with potential antineoplastic activity.
价 格:¥电议型 号:T2349产 地:中国大陆
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T2337BMS-303141;化合物BMS-303141BMS 303141;BMS 303141
BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).
价 格:¥电议型 号:T2337产 地:中国大陆
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T2299BMS-833923;化合物BMS-833923XL-139;XL-139
BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).
价 格:¥电议型 号:T2299产 地:中国大陆
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T22612BMY-14802 hydrochloride;化合物BMY-14802盐酸盐BMS 181100 hydrochloride|||BMY-14802-1|||BMY 14802 hydrochlor
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is an agonist of the α1-adrenergic receptor and 5-HT1A.
价 格:¥电议型 号:T22612产 地:中国大陆
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T22611BMS 961;化合物 T22611BMS 961
BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist (IC50: 30 nM).
价 格:¥电议型 号:T22611产 地:中国大陆
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T22609BMS-378806;化合物 T22609BMS-378806
BMS-378806 is a novel attachment inhibitor of HIV (EC50: 2.68±1.64nM, 26.5±3.5nM, 2.94±2.01nM,15.5±6.8nM, 3.46±0.81nM, 1.47±0.63nM and 0.85±0.13nM for LAI(T), SF-2(T),NL4-3(T), Bal(M), SF-162(M), JRFL(M) and TLAV(dual), respectively).
价 格:¥电议型 号:T22609产 地:中国大陆