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T36502DCP-Rho1;DCP-Rho1DCP-Rho1;DCP-Rho1
DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in situ.
价 格:¥电议型 号:T36502产 地:中国大陆
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T3626Acalabrutinib;阿可替尼ACP-196;ACP-196|||阿可替尼
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton´s tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. BTK, a member
价 格:¥电议型 号:T3626产 地:中国大陆
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T3622CP-640186 hydrochloride;盐酸CP-640186CP 640186 HCl;CP 640186 HCl|||盐酸CP-640186
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stability than CP-610431.
价 格:¥电议型 号:T3622产 地:中国大陆
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T35956PAz-PC;PAz-PCPAz-PC
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were isolated and purified from oxLDL and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. PAz-PC is one of the predominant oxLDL species and may be one of the important structural determinants of oxLDL.
价 格:¥电议型 号:T35956产 地:中国大陆
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T35910Petromurin C;Petromurin CPetromurin C
Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vitro (IC50 = 100 μg/ml).
价 格:¥电议型 号:T35910产 地:中国大陆
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T3576CPI-455 analogue;化合物 CPI-455 analogueCPI-455 analogue;CPI-455 analogue
CPI-455 analogue (CPI-455 analogue) is an analogue of CPI-455 which is a KDM5 inhibitor.
价 格:¥电议型 号:T3576产 地:中国大陆
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T3561CPI1189;化合物CPI1189CPI-1189|||REN-1189|||CPI 1189;CPI-1189|||REN-1189|||CPI 1189
CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
价 格:¥电议型 号:T3561产 地:中国大陆
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T35593Semapimod tetrahydrochloride;塞马莫德盐酸盐CPSI-2364 tetrahydrochloride;CPSI-2364 tetrahydrochloride
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microglia function. Sematimod tetrahydrochloride inhibits TLR4 signaling, TNF-α, IL-1β, and IL-6, and is used in the study of Crohn´s disease and other inflammatory conditions.
价 格:¥电议型 号:T35593产 地:中国大陆
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T35580POV-PC;POV-PCPOV-PC
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-oxovaleroyl)-phosphatidylcholine, or POV-PC, is one of the oxLDL species derived from 2-arachidonoyl or eicosapentanoyl phospholipids. POV-PC conf
价 格:¥电议型 号:T35580产 地:中国大陆
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T3552CPI-455;化合物CPI455CPI-455 HCl;CPI-455 HCl
CPI-455 is a specific KDM5 inhibitor.
价 格:¥电议型 号:T3552产 地:中国大陆
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T35349CU-CPD107;化合物CU-CPD107CU-CPD107;CU-CPD107
CU-CPD107 is a selective agonist of toll-like receptor 8 (TLR8) and also shows activation activity against ssRNA ligands. CU-CPD107 acts as an inhibitor of TLR8 signaling in the presence of R848 (IC50=13.7 μM). CU-CPD107 exhibited coagonist activity in the presence of ssRNA, while CU-CPD107 alone could not affect TLR8 signal transduction.
价 格:¥电议型 号:T35349产 地:中国大陆
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T35338CP2;CP2CP2
CP2是一种环肽,能够抑制JmjC histone demethylases KDM4,对KDM4A 和KDM4C 的IC50分别为42 nM 和29 nM。
价 格:¥电议型 号:T35338产 地:中国大陆
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T35317Zopolrestat;唑泊司他CP 73850|||CP73850|||CP-73850|||Zopolrestatum;CP 73850|||CP73850|||CP-73850|||唑泊司他||
Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).
价 格:¥电议型 号:T35317产 地:中国大陆
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T3530Otenabant;奥替那班CP-945598;CP-945598|||奥替那班
Otenabant (CP-945598) has been investigated for the treatment of Obesity.
价 格:¥电议型 号:T3530产 地:中国大陆
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T35103W7477;化合物 T35103BRN 0626598|||W 7477|||W-7477|||CP 14304;BRN 0626598|||W 7477|||W-7477|||CP 14304
W7477 is a biochemical.
价 格:¥电议型 号:T35103产 地:中国大陆
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T34945Trimazosin hydrochloride;化合物 T34945CP19106-1|||CP 19106-1|||Trimazosin HCl|||CP-19106-1;CP19106-1|||
Trimazosin hydrochloride is used in the treatment of hypertensive patients failing to respond to thiazides.
价 格:¥电议型 号:T34945产 地:中国大陆
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T3484trans-ACPD;化合物(±)-trans-ACPDTrans-(±)-ACP|||1-amino-1,3-dicarboxycyclopentane|||(±)-trans-ACPD;Trans
trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); active at the group I/II mGlu receptors (EC50: 2/15/23/800 μM, mGluR2/1/5/4).
价 格:¥电议型 号:T3484产 地:中国大陆
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T34801Temodox;化合物 T34801CP-22,341|||CP22341|||CP-22341|||CP 22341|||CP 22,341;CP-22,341|||CP22341|||CP-223
Temodox, also known as CP 22341, is a bioactive chemical.
价 格:¥电议型 号:T34801产 地:中国大陆
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T34791TCCP;化合物 T34791TCCP
TCCP is a natural inducer of apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
价 格:¥电议型 号:T34791产 地:中国大陆
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T3479(RS)-MCPG;化合物(RS)-MCPGalpha-MCPG|||(±)-MCPG;alpha-MCPG|||(±)-MCPG
(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.
价 格:¥电议型 号:T3479产 地:中国大陆