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T10624BT-13;化合物BT-13BT-13
BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro.
价 格:¥电议型 号:T10624产 地:中国大陆
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T10623BSH-IN-1;化合物BSH-IN-1BSH-IN-1
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH).
价 格:¥电议型 号:T10623产 地:中国大陆
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T10622BSc5371;化合物 T10622BSc5371
BSc5371 is a potent and irreversible FLT3 inhibitor (Kds: 1.3, 0.83, 1.5, 5.8, and 2.3 nM for mutant FLT3 D835H, FLT3 ITD/D835V, FLT3 ITD/F691L, FLT3-ITD, and wild type FLT3 wt).
价 格:¥电议型 号:T10622产 地:中国大陆
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T10621Bromodomain inhibitor-8;化合物 T10621Bromodomain inhibitor-8
Bromodomain inhibitor-8 is an inhibitor of BET bromodomain used to treat autoimmune and inflammatory diseases.
价 格:¥电议型 号:T10621产 地:中国大陆
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T10620Bromodomain IN-1;化合物 T10620Bromodomain IN-1
Bromodomain IN-1 is an inhibitor of Bromodomain.
价 格:¥电议型 号:T10620产 地:中国大陆
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T1062Capsaicin;辣椒素Qutenza|||8-Methyl-N-vanillyl-trans-6-nonenamide|||Vanilloid|||(E)-Capsaicin|||Zostrix;
Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
价 格:¥电议型 号:T1062产 地:中国大陆
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T10567BMS-214662;化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格:¥电议型 号:T10567产 地:中国大陆
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T10563L2BM635 mesylate (1493762-74-5 free base);化合物 T10563L2BM635 mesylate;BM635 mesylate
BM635 mesylate is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
价 格:¥电议型 号:T10563L2产 地:中国大陆
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T10563LBM635 hydrochloride (1493762-74-5 free base);化合物 T10563LBM635 hydrochloride;BM635 hydrochloride
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
价 格:¥电议型 号:T10563L产 地:中国大陆
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T10562(4-Acetamidocyclohexyl) nitrate;化合物 T10562BM121307;BM121307
(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.
价 格:¥电议型 号:T10562产 地:中国大陆
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T10541Bicyclomycin benzoate;化合物 T10541FR2054;FR2054|||CS-6253
Bicyclomycin benzoate, an antibiotic, exhibits activity against a broad spectrum of Gram-negative/Gram-positive bacteria.
价 格:¥电议型 号:T10541产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆
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T10462Bavisant dihydrochloride;化合物 T10462Bavisant dihydrochloride
Bavisant (JNJ-310010740) dihydrochloride is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition.
价 格:¥电议型 号:T10462产 地:中国大陆
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T10362LAR453588 hydrochloride;化合物 T10362LAR453588 hydrochloride
AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.
价 格:¥电议型 号:T10362L产 地:中国大陆
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T10362AR453588化合物 T10362AR-453588|||AR453588
AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.
价 格:¥电议型 号:T10362产 地:中国大陆
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T1034Docetaxel;多西他赛NSC 628503|||RP-56976;多西他赛|||NSC 628503|||RP-56976|||多烯紫杉醇
Docetaxel (RP-56976) is a semi-synthetic analog of paclitaxel, a microtubule depolymerization inhibitor (IC50=0.2 μM). Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing, anti-tumor activity.
价 格:¥电议型 号:T1034产 地:中国大陆
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T10262AGN 205327;化合物 T10262AGN 205327
AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively without inhibition of RXR. IC50 value: 3766/734/32 nM for RARα/β/γ Target: RAR agonist
价 格:¥电议型 号:T10262产 地:中国大陆
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T10243Ibezapolstat;化合物 T10243ACX-362E;ACX-362E
ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections (MIC50: 2 μg/mL for C. difficile).
价 格:¥电议型 号:T10243产 地:中国大陆
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T10240ACP-5862;化合物 T10240ACP-5862
ACP-5862 is a major active and pyrrolidine ring-opened metabolite of Acalabrutinib (IC50: 5.0 nM for BTK). Acalabrutinib is an irreversible and highly selective BTK inhibitor (IC50: 3 nM; EC50: 8 nM).
价 格:¥电议型 号:T10240产 地:中国大陆
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T101625-HT3 antagonist 3;5-HT3拮抗剂35-HT3 antagonist 3
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).
价 格:¥电议型 号:T10162产 地:中国大陆