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T11090L1Aldoxorubicin hydrochloride;化合物Aldoxorubicin盐酸盐Aldoxorubicin hydrochloride (1361644-26-9 Free base);
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin under acidic conditions. Aldoxorubicin hydrochloride exhibits potent antitumor activities in various cancer cell lines and in murine tumor models.
价 格:¥电议型 号:T11090L1产 地:中国大陆
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T11069DO-264;化合物 DO-264DO-264
DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) (IC50: 11 nM) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.
价 格:¥电议型 号:T11069产 地:中国大陆
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T11064DMT1 blocker 2;化合物DMT1 blocker 2DMT1 blocker 2
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo.
价 格:¥电议型 号:T11064产 地:中国大陆
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T10964LDB1976 dihydrochloride;DB1976盐酸盐DB1976 hydrochloride|||DB1976 2HCl;DB1976 hydrochloride|||DB1976 2HC
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T10964L产 地:中国大陆
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T10964DB1976;化合物DB1976DB1976
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 has Apoptosis-inducing effect.
价 格:¥电议型 号:T10964产 地:中国大陆
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T10883LCRA-026440 hydrochloride;化合物CRA-026440盐酸盐CRA-026440 hydrochloride(847460-34-8 Free base);CRA-026440
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
价 格:¥电议型 号:T10883L产 地:中国大陆
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T10883CRA-026440;化合物CRA-026440PCI-34051;PCI-34051
CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-angiogenic activity and can be used to study colon cancer.
价 格:¥电议型 号:T10883产 地:中国大陆
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T10873CP-96486;化合物 T10873CP-96486
CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM).
价 格:¥电议型 号:T10873产 地:中国大陆
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T10864Corin;化合物CorinCorin
Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).
价 格:¥电议型 号:T10864产 地:中国大陆
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T10833CL264;化合物CL264CL264
CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.
价 格:¥电议型 号:T10833产 地:中国大陆
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T1077Fluvoxamine maleate;氟伏沙明马来酸盐MK-264|||DU-23000 (maleate);氟伏沙明马来酸盐|||马来酸氟伏沙明|||MK-264|||DU-23000 (male
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
价 格:¥电议型 号:T1077产 地:中国大陆
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T10764Cercosporamide;化合物 T10764(-)-Cercosporamide;(-)-Cercosporamide
Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.
价 格:¥电议型 号:T10764产 地:中国大陆
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T10693CB-6644;化合物CB-6644CB-6644
CB-6644 is a selective inhibitor of the RUVBL1/2 complex and blocks the ATPase activity of RUVBL1/2 (IC50 = 15 nM).
价 格:¥电议型 号:T10693产 地:中国大陆
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T10686Carvedilol metabolite 4-Hydroxyphenyl Carvedilol;化合物 T106864-Hydroxyphenyl Carvedilol|||4-Hydroxycar
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker.
价 格:¥电议型 号:T10686产 地:中国大陆
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T10664Calcium 2-oxoglutarate;化合物 T10664Calcium 2-oxoglutarate
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
价 格:¥电议型 号:T10664产 地:中国大陆
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T10649c-Fms-IN-3;化合物c-Fms-IN-3c-Fms-IN-3
c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.
价 格:¥电议型 号:T10649产 地:中国大陆
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T10648c-Fms-IN-9;化合物 T10648c-Fms-IN-9
c-Fms-IN-9 is a c-FMS inhibitor. It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).
价 格:¥电议型 号:T10648产 地:中国大陆
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T10647c-Fms-IN-8;化合物 T10647c-Fms-IN-8
c-Fms-IN-8 is a colony-stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor (IC50: 9.1 nM). It is compound 4a in the reference.
价 格:¥电议型 号:T10647产 地:中国大陆
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T10646c-Fms-IN-7;化合物 T10646c-Fms-IN-7
c-Fms-IN-7 is a cFMS inhibitor (IC50: 18.5 nM).
价 格:¥电议型 号:T10646产 地:中国大陆
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T10645c-Fms-IN-6;化合物 T10645c-Fms-IN-6
c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 μM).
价 格:¥电议型 号:T10645产 地:中国大陆