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T12929SKF-34288 hydrochloride;3 - 巯基吡啶甲酸3-Mercaptopicolinic acid hydrochloride;3 - 巯基吡啶甲酸|||3-Mercaptopico
SKF-34288 hydrochloride (3-Mercaptopicolinic acid hydrochloride) is an inhibitor of phosphoenolpyruvate carboxykinase (PEPCK),and inhibits Asn metabolism and results in an increase in amino acids and amides.
价 格:¥电议型 号:T12929产 地:中国大陆
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T12928SK33;化合物SK33SK33
SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.
价 格:¥电议型 号:T12928产 地:中国大陆
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T12927SK1-IN-1;化合物 T12927SK1-IN-1
SK1-IN-1 is a potent inhibitor of sphingosine kinase 1 (SPHK1)(IC50 of 58 nM).
价 格:¥电议型 号:T12927产 地:中国大陆
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T12926SJB3-019A;化合物SJB3-019ASJB3-019A
SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis.
价 格:¥电议型 号:T12926产 地:中国大陆
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T12925Sitravatinib malate;化合物 T12925MGCD516 malate|||MG-516 malate;MGCD516 malate|||MG-516 malate
Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively.) , shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment.
价 格:¥电议型 号:T12925产 地:中国大陆
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T12924Sitaxsentan;司他生坦TBC-11251|||IPI 1040;TBC-11251|||IPI 1040
Sitaxsentan (TBC-11251) is A selective endothelin A (ETA) receptor antagonist. Endothelin is an effective vasoconstrictor. Sitaxsentan blocks the binding of endothelin to its receptors, thereby eliminating the harmful effects of endothelin.
价 格:¥电议型 号:T12924产 地:中国大陆
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T12923(Rac)-SIS3 free base;化合物 T12923(Rac)-SIS3 free base
SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
价 格:¥电议型 号:T12923产 地:中国大陆
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T12922Sirtuin modulator 1;化合物Sirtuin modulator 1SRT3025 Hydrochloride;SRT3025 Hydrochloride
Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.
价 格:¥电议型 号:T12922产 地:中国大陆
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T12921SIRT5 inhibitor 1;SIRT5抑制剂`SIRT5 inhibitor 1
SIRT5 inhibitor 1 is a potent and selective inhibitor of human Sirtuin 5 deacylase (IC50: 0.11 μM). sIRT5 inhibitor 1 is associated with ageing-related diseases.
价 格:¥电议型 号:T12921产 地:中国大陆
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T12920Sirt2-IN-1;化合物Sirt2-IN-1Sirt2-IN-1
Sirt2-IN-1 is an inhibitor of sirtuin 2 (IC50 = 163 nM).
价 格:¥电议型 号:T12920产 地:中国大陆
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T1292Tiapride hydrochloride;盐酸硫必利Tiapride hydrochloride
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdrawal syndrome, and aggression and agitation in the elderly.
价 格:¥电议型 号:T1292产 地:中国大陆
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T12919SIRT-IN-2;化合物SIRT-IN-2SIRT-IN-2
SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).
价 格:¥电议型 号:T12919产 地:中国大陆
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T12918SIRT-IN-1;化合物SIRT-IN-1SIRT-IN-1
SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively).
价 格:¥电议型 号:T12918产 地:中国大陆
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T12917Siomycin A;盐霉素 ASiomycin A
Siomycin A is a thiopeptide antibiotic and is a selective inhibitor of Forkhead box M1(FOXM1) without affecting other members of the Forkhead box family, has anti-tumor and promotes apoptosis.
价 格:¥电议型 号:T12917产 地:中国大陆
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T12916Silvestrol aglycone;化合物 T12916Silvestrol aglycone
Silvestrol aglycone is an analogue of Silvestrol, inhibits protein translation initiation in cancer cells(EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively), with nti-cancer activity.
价 格:¥电议型 号:T12916产 地:中国大陆
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T12915Silvestrol aglycone (enantiomer);化合物 T12915Silvestrol aglycone (enantiomer)
Silvestrol aglycone (enantiomer) is a cyclopenta benzofuran core phenol.
价 格:¥电议型 号:T12915产 地:中国大陆
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T12914Siltenzepine;西腾西平Siltenzepine
Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.
价 格:¥电议型 号:T12914产 地:中国大陆
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T12913Siguazodan;化合物SiguazodanSKF 94836;SKF 94836
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM。 Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM。
价 格:¥电议型 号:T12913产 地:中国大陆
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T12912Sigma-1 receptor antagonist 3;化合物Sigma-1 receptor antagonist 3Sigma-1 receptor antagonist 3
Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)
价 格:¥电议型 号:T12912产 地:中国大陆
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T12911Sigma-1 receptor antagonist 2;化合物Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
价 格:¥电议型 号:T12911产 地:中国大陆