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T11002Desethylamiodarone hydrochloride;化合物 T11002N-desethylamiodarone hydrochloride|||LB 33020 hydrochlori
Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is formed by the CYP3A isozyme. Amiodarone is an antiarrhythmic drug that inhibits ATP-sensitive potassium channels with an IC50 of 19.1 μM. It is the main active metabolite of amiodarone.
价 格:¥电议型 号:T11002产 地:中国大陆
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T11001L1N-Desethyl Chloroquine Hydrochloride;化合物T11001L1(±)-Desethylchloroquine 2HCl;(±)-Desethylchloroquine
N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo.
价 格:¥电议型 号:T11001L1产 地:中国大陆
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T10994LDeltasonamide 2 hydrochloride;化合物 T10994LDeltasonamide 2 hydrochloride (2088485-34-9 free base);Delt
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.
价 格:¥电议型 号:T10994L产 地:中国大陆
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T10983LDDP-38003 dihydrochloride;DDP-38003盐酸盐DDP-38003 dihydrochloride
DDP-38003 dihydrochloride is an orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor (IC50: 84 nM).
价 格:¥电议型 号:T10983L产 地:中国大陆
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T10983DDP-38003 trihydrochloride;化合物 T10983DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.
价 格:¥电议型 号:T10983产 地:中国大陆
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T10964LDB1976 dihydrochloride;DB1976盐酸盐DB1976 hydrochloride|||DB1976 2HCl;DB1976 hydrochloride|||DB1976 2HC
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
价 格:¥电议型 号:T10964L产 地:中国大陆
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T10951Dabigatran ethyl ester hydrochloride化合物T10951N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-
Dabigatran ethyl ester hydrochloride is an effective inhibitor of ribosyl dihydronicotinic acid amide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and is a thrombin inhibitor.
价 格:¥电议型 号:T10951产 地:中国大陆
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T10950Dabigatran D4 hydrochloride;化合物 T10950BIBR-953 D4 hydrochloride;BIBR-953 D4 hydrochloride
Dabigatran D4 hydrochloride is deuterium-labeled dabigatran, which is a reversible and selective direct thrombin inhibitor (DTI) with a Ki value of 4.5 nM.
价 格:¥电议型 号:T10950产 地:中国大陆
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T10939D,L-Cystathionine dihydrochloride;化合物 T10939D,L-Cystathionine dihydrochloride
D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cysteine (βC-S) carbon-sulfur bond.
价 格:¥电议型 号:T10939产 地:中国大陆
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T10931d-Atabrine dihydrochloride;化合物 T10931d-Atabrine dihydrochloride
d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.
价 格:¥电议型 号:T10931产 地:中国大陆
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T10929LD-3263 hydrochloride;化合物D-3263 盐酸盐EC D-3263 HCl|||D3263 HCl salt;EC D-3263 HCl|||D3263 HCl salt
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
价 格:¥电议型 号:T10929L产 地:中国大陆
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T10926LCYT-1010 hydrochloride;化合物 T10926LCYT-1010 hydrochloride
CYT-1010 hydrochloride is an mu-opioid receptor agonist. The EC50 for β-arrestin recruitment and cAMP production inhibition were 13.1 nM and 0.0053 nM, respectively.
价 格:¥电议型 号:T10926L产 地:中国大陆
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T10925LCysteine Protease inhibitor hydrochloride;化合物 T10925LCysteine Protease inhibitor hydrochloride (9216
Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.
价 格:¥电议型 号:T10925L产 地:中国大陆
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T10914Cyclodrine hydrochloride;环戊君盐酸盐Cyclodrine hydrochloride
Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study of neurologically related diseases.
价 格:¥电议型 号:T10914产 地:中国大陆
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T10898Samuraciclib hydrochloride;化合物Samuraciclib hydrochlorideICEC0942 hydrochloride|||CT7001 hydrochlorid
Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.
价 格:¥电议型 号:T10898产 地:中国大陆
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T10896LCSRM617 hydrochloride;盐酸CSRM617CSRM617 hydrochloride(787504-88-5 Free base);CSRM617 hydrochloride(78
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]
价 格:¥电议型 号:T10896L产 地:中国大陆
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T10888CRT0066854 hydrochloride;化合物CRT0066854盐酸盐CRT0066854 hydrochloride
CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
价 格:¥电议型 号:T10888产 地:中国大陆
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T10883LCRA-026440 hydrochloride;化合物CRA-026440盐酸盐CRA-026440 hydrochloride(847460-34-8 Free base);CRA-026440
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
价 格:¥电议型 号:T10883L产 地:中国大陆
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T10872CP-96021 hydrochloride;化合物 T10872CP-96021 hydrochloride
CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).
价 格:¥电议型 号:T10872产 地:中国大陆
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T10871CP-809101 hydrochloride;2-[(3-氯苯基)甲氧基]-6-(1-哌嗪基)吡嗪盐酸盐CP-809101 hydrochloride
CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
价 格:¥电议型 号:T10871产 地:中国大陆