TPL03664-Biphenylcarboxylic acid4 Biphenylcarboxylic acid,4Biphenylcarboxylic acid

价 格：￥电议型 号：TPL0366产 地：中国大陆

T6717Vanillininhibit,Vanillin,Inhibitor,Endogenous Metabolite

Vanillin is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.Vanillin can reversibly and non-competitively inhibit the cellulase activity at appropriate concentrations and the value of IC50 was estimated to be 30 g/L.Vanillin protects KSC from UVB irradiation and its effects may occur through the suppression of downstream step of MDM2 in UVB irradiation-induced p53 activation. Vanillin also inhibits yeast growth and fermentation.

价 格：￥电议型 号：T6717产 地：中国大陆

T9531MRT-14Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14

MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.

价 格：￥电议型 号：T9531产 地：中国大陆

T35341NVP-BSK805 dihydrochloride

NVP-BSK805 dihydrochloride is an effective and selective inhibitor of JAK2 with IC50s of 0.5 nM, 10.76 nM, 18.68 nM, and 31.63 nM for JAK2, TYK2, JAK3, and JAK1.

价 格：￥电议型 号：T35341产 地：中国大陆

T21861Drinabant

Drinabant is an orally active CB1 receptor antagonist. Drinabant inhibits the agonist-stimulated calcium signal with IC50 values of 25 nM and 10 nM for the hCB1-R and rCB1-R, respectively, and is ineffective for the hCB2-R.

价 格：￥电议型 号：T21861产 地：中国大陆

T11358gamma-secretase modulator 1

gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer´s disease.

价 格：￥电议型 号：T11358产 地：中国大陆

T1782LCanagliflozin hemihydrate

Canagliflozin hemihydrate is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.

价 格：￥电议型 号：T1782L产 地：中国大陆

TN6775AcetylcytisineAcetylcytisine

Acetylcytisine is a natural product of The herbs of Genista tinctoria L.

价 格：￥电议型 号：TN6775产 地：中国大陆

T7297KG-501Epigenetic Reader Domain,inhibit,Inhibitor,KG 501,Naphthol AS-E,KG501,KG-501

KG-501 is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).

价 格：￥电议型 号：T7297产 地：中国大陆

T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE

Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.

价 格：￥电议型 号：T7846产 地：中国大陆

TWS2045Bruceine DParasite,Notch,Apoptosis,Bruceine D,Inhibitor,inhibit

1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.

价 格：￥电议型 号：TWS2045产 地：中国大陆

T6940PHA-767491 hydrochloridePHA767491,PHA 767491,inhibit,CAY-10572,Cyclin dependent kinase,CDK,CAY 10572

PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.

价 格：￥电议型 号：T6940产 地：中国大陆

T31425Dibenz[a,h]anthracene

Dibenz[a,h]anthracene has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell cultures.

价 格：￥电议型 号：T31425产 地：中国大陆

T7117Sapropterin dihydrochloride(6R)-BH4,Sapropterin,Inhibitor,inhibit,Sapropterin dihydrochloride

Sapropterin dihydrochloride is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.

价 格：￥电议型 号：T7117产 地：中国大陆

T6S1572Sauchinoneantioxidant,LPS,Diastereomeric,TNF-α,iNOS,anti-inflammatory,lignan,COX-2,inhibit,Nuclear f

1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhi

价 格：￥电议型 号：T6S1572产 地：中国大陆

T80582-Methyl-4-pentenoic Acidinhibit,Inhibitor,2 Methyl 4 pentenoic Acid,2Methyl4pentenoic Acid

2-Methyl-4-pentenoic acid is a branched-chain fatty acid.

价 格：￥电议型 号：T8058产 地：中国大陆

T2573MisoprostolMisoprostol

价 格：￥电议型 号：T2573产 地：中国大陆

T22808GR 46611

GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.

价 格：￥电议型 号：T22808产 地：中国大陆

T40146Sec61-IN-1Sec61IN1,Sec61 IN 1,Sec-61-IN-1

Sec61-IN-1 is a potent sec61 inhibitor (Patent WO2020176863A1, compound A317).

价 格：￥电议型 号：T40146产 地：中国大陆

Fr212652-Methyl-2H-indazole-3-carboxylic acid

价 格：￥电议型 号：Fr21265产 地：中国大陆