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T10899CU-CPT17e；化合物CU-CPT17eCU-CPT17e
CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
价 格：￥电议型 号：T10899产 地：中国大陆
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T10898Samuraciclib hydrochloride；化合物Samuraciclib hydrochlorideICEC0942 hydrochloride|||CT7001 hydrochlorid
Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.
价 格：￥电议型 号：T10898产 地：中国大陆
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T10897CT-721；化合物 T10897CT-721
CT-721 is a potent and time-dependent Bcr-Abl kinase inhibitor with an IC50 of 21.3 nM against wild-type Bcr-Abl kinase and has anti-chronic myeloid leukemia (CML) activity.
价 格：￥电议型 号：T10897产 地：中国大陆
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T10896LCSRM617 hydrochloride；盐酸CSRM617CSRM617 hydrochloride(787504-88-5 Free base)；CSRM617 hydrochloride(78
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the mouse model of prostate cancer [1]
价 格：￥电议型 号：T10896L产 地：中国大陆
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T10896CSRM617；化合物 T10896CSRM617
CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2, the main regulator of androgen receptor). The Kd in SPR analysis is 7.43 uM, which can directly bind to the OC2-HOX domain. CSRM617 induces apoptosis by cleaving the presence of Caspase-3 and PARP. CSRM617 is well tolerated in a mouse model of prostate cancer.
价 格：￥电议型 号：T10896产 地：中国大陆
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T10895CSN5i-3；化合物CSN5i-3CSN5i-3
CSN5i-3 is a novel potent oral and selective CSN5/Jab1 inhibitor that inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM.CSN5i-3 exhibits anticancer activity, inhibits cell proliferation and induces apoptosis in human breast cancer cells.
价 格：￥电议型 号：T10895产 地：中国大陆
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T10894CSF1R-IN-1；化合物CSF1R-IN-1CSF1R-IN-1
CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.
价 格：￥电议型 号：T10894产 地：中国大陆
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T10893CS-722 Free base；化合物CS-722 Free baseCS-722 Free base
CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-synaptic current in hippocampal culture by inhibiting sodium current and calcium current.
价 格：￥电议型 号：T10893产 地：中国大陆
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T10892CS-003 Free base；化合物 T10892CS-003 Free base
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on neurokinin-related respiratory diseases.
价 格：￥电议型 号：T10892产 地：中国大陆
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T10891CRTH2-IN-1；化合物 T10891Ramatroban analog；Ramatroban analog
CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.
价 格：￥电议型 号：T10891产 地：中国大陆
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T10889CRTh2 antagonist 2；CRTh2拮抗剂2CRTh2 antagonist 2
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
价 格：￥电议型 号：T10889产 地：中国大陆
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T10888CRT0066854 hydrochloride；化合物CRT0066854盐酸盐CRT0066854 hydrochloride
CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.
价 格：￥电议型 号：T10888产 地：中国大陆
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T10887CRS400393；化合物 T10887CRS400393
CRS400393 is an effective anti-mycobacterial drug , with MIC of 0.03, 2, and ≤ 0.12 μg/mL against M. abs., M. avium, M. intracellulare, and M. tuberculosis, respectively.
价 格：￥电议型 号：T10887产 地：中国大陆
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T10886Crocetine dimethyl ester；化合物 Crocetine dimethyl esterDimethylcrocetin；Dimethylcrocetin
Crocetine dimethyl ester (Dimethylcrocetin) is a saffronin derivative with antioxidant activity, inhibition of AChE activity, and inhibition of cell growth and differentiation.
价 格：￥电议型 号：T10886产 地：中国大陆
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T10885CRAC intermediate 2；4-(3,5-双(三氟甲基)-1H-吡唑-1-基)-苯胺CRAC intermediate 2
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.
价 格：￥电议型 号：T10885产 地：中国大陆
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T10884CRAC intermediate 1化合物CRAC intermediate 15-(S)-Fluorowillardiine
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.
价 格：￥电议型 号：T10884产 地：中国大陆
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T10883LCRA-026440 hydrochloride；化合物CRA-026440盐酸盐CRA-026440 hydrochloride（847460-34-8 Free base）；CRA-026440
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
价 格：￥电议型 号：T10883L产 地：中国大陆
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T10883CRA-026440；化合物CRA-026440PCI-34051；PCI-34051
CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7 and 20 nM, respectively. CRA-026440 has anti-tumor and anti-angiogenic activity and can be used to study colon cancer.
价 格：￥电议型 号：T10883产 地：中国大陆
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T10882CPUY074020；化合物CPUY074020CPUY074020
CPUY074020 is a potent and orally bioavailable inhibitor of histone methyltransferase G9a (IC50: 2.18 μM) with anti-proliferative activity.
价 格：￥电议型 号：T10882产 地：中国大陆
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T10881CPPHA；化合物CPPHACPPHA
CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.
价 格：￥电议型 号：T10881产 地：中国大陆
