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T11681Isochondrodendrine;化合物 T11681Isochondrodendrin;Isochondrodendrin
Isochondodendrine has strong antiplasmodial activity against Plasmodium falciparum. Isochondrodendrine is a class of bisbenzylisoquinoline alkaloid isolated from Isolona ghesquiereina.
价 格:¥电议型 号:T11681产 地:中国大陆
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T11680Isoasatone A;异细辛酮 AIsoasatone A
Isoasatone A acts against S. litura by acting on cytochrome P450 monooxygenase and glutathione transferase. Isoasatone A is a natural product isolated from Heterotropa takaoi M..
价 格:¥电议型 号:T11680产 地:中国大陆
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T1168Desonide地索奈德Tridesilon|||地索奈德|||Locapred|||Prednacinolone
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-
价 格:¥电议型 号:T1168产 地:中国大陆
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T11677Irindalone;化合物 T11677Lu 21-?098;Lu 21-?098
IrindaloneIrindalone is a potent serotonin (5-HT2) antagonist.
价 格:¥电议型 号:T11677产 地:中国大陆
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T11676Iriflophenone 3-C-glucoside;化合物Iriflophenone 3-C-glucosideIriflophenone 3-C-β-D-glucopyranoside;Irif
Iriflophenone 3-C-glucoside (Iriflophenone 3-C-β-D-glucopyranoside),has antioxidant activity,isolated from Cyclopia genistoides.
价 格:¥电议型 号:T11676产 地:中国大陆
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T11675Irbesartan-d4;厄贝沙坦 D4SR-47436 D4|||BMS-186295 D4;厄贝沙坦 D4|||SR-47436 D4|||BMS-186295 D4
Irbesartan D4, a deuterium-labeled variant of Irbesartan, is a highly potent and specific antagonist of the angiotensin II type 1 (AT1) receptor.
价 格:¥电议型 号:T11675产 地:中国大陆
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T11674IRAK4-IN-6;化合物 T11674IRAK4-IN-6
IRAK4-IN-6 is a selective and orally efficacious inhibitor of IRAK4, demonstrating an IC50 value of 4 nM. This compound specifically targets MyD88 L265P mutant diffuse large B-cell lymphoma [1].
价 格:¥电议型 号:T11674产 地:中国大陆
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T11673IRAK4-IN-4;化合物IRAK4-IN-4IRAK4-IN-4
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
价 格:¥电议型 号:T11673产 地:中国大陆
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T11672IRAK inhibitor 4;化合物 T11672IRAK inhibitor 4
IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.
价 格:¥电议型 号:T11672产 地:中国大陆
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T11671IRAK inhibitor 4 trans;化合物 T11671IRAK inhibitor 4 trans
IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers to its specific molecular configuration.
价 格:¥电议型 号:T11671产 地:中国大陆
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T11670IRAK inhibitor 3;化合物IRAK inhibitor 3IRAK inhibitor 3
IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.
价 格:¥电议型 号:T11670产 地:中国大陆
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T1167Cyproterone acetate醋酸环丙孕酮Androcur|||醋酸环丙氯地孕酮|||Cyproterone 17-O-acetate|||醋酸环丙孕酮
Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. Cyproterone acetate is the acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductio
价 格:¥电议型 号:T1167产 地:中国大陆
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T11669IR415;化合物IR415IR415
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 is a potent anti-HBV agent and inhibits HBV replication by blocking the HBx activity.
价 格:¥电议型 号:T11669产 地:中国大陆
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T11668IQB-782;化合物 IQB-782IQB-782
IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction, reduces the viscosity of gastric mucin suspensions in vitro, and may be useful in studies of obstructive lung disease.IQB-782 has been shown to reduce the viscosity of gastric mucin suspensions in vitro.
价 格:¥电议型 号:T11668产 地:中国大陆
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T11667Ipragliflozin (L-Proline)化合物 T11667Ipragliflozin L-Proline
Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6.
价 格:¥电议型 号:T11667产 地:中国大陆
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T11666IPR-803;化合物IPR-803IPR-803
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM.
价 格:¥电议型 号:T11666产 地:中国大陆
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T11665Ionomycin calcium;罗红霉素钙盐(链霉菌属载体)SQ23377 calcium;SQ23377 calcium|||罗红霉素钙盐(链霉菌属载体)
lonomycin calcium is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. also induces the activation of protein kinase C (PKC). Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin promotes apoptosis.
价 格:¥电议型 号:T11665产 地:中国大陆
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T11664INY-03-041;化合物 T11664INY-03-041
INY-03-041, a potent and highly selective PROTAC-based pan-AKT degrader, inhibits AKT1, AKT2, and AKT3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively. This compound consists of the ATP-competitive AKT inhibitor GDC-0068 conjugated to Lenalidomide.
价 格:¥电议型 号:T11664产 地:中国大陆
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T11663Integrin-IN-2;化合物 T11663Integrin-IN-2
Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
价 格:¥电议型 号:T11663产 地:中国大陆
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T11662LINT-777;化合物INT-777S-EMCA;S-EMCA
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.
价 格:¥电议型 号:T11662L产 地:中国大陆