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T12751RORγt agonist 1;化合物 T12751RORgammat agonist 1|||RORγt agonist 1|||RORγt agonist 1|||RORrt agonist 1;
RORγt agonist 1 is a potent, orally bioavailable agonist of RORγt(EC50 of 20.8 nM).
价 格:¥电议型 号:T12751产 地:中国大陆
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T12750ROR agonist-1;化合物 T12750ROR agonist-1
ROR agonist-1 is a potent and orally bioavailable the retinoic acid receptor-related orphan receptor C2 (RORC2) inverse agonist(inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5).
价 格:¥电议型 号:T12750产 地:中国大陆
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T1275Phentolamine mesylate;甲磺酸酚妥拉明Phentolamine methanesulfonate|||Phentolamine mesilate;Phentolamine meth
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
价 格:¥电议型 号:T1275产 地:中国大陆
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T12749Roflumilast Impurity E;罗氟司特杂质ERoflumilast Impurity E
Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast acts as a selective and long-acting the enzyme PDE-4 inhibitor(IC50 value of 0.8 nM).
价 格:¥电议型 号:T12749产 地:中国大陆
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T12748Rocuronium;罗库铵Org-9426;罗库铵|||Org-9426
Rocuronium is an blocker of aminosteroid non-depolarizing neuromuscular.
价 格:¥电议型 号:T12748产 地:中国大陆
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T12747ROCK2-IN-2;化合物ROCK2-IN-2ROCK2-IN-2
ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
价 格:¥电议型 号:T12747产 地:中国大陆
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T12746ROCK inhibitor-2;化合物ROCK inhibitor-2ROCK inhibitor-2
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).
价 格:¥电议型 号:T12746产 地:中国大陆
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T12745L(4R)-RO5263397;化合物T12745L(4R)-RO5263397
(4R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamin was active against TRACE AMINE ASSOCIATED RECEPTOR (TAAR 1) with an EC50 of 0.017 μM and could be used to study neurological disorders.
价 格:¥电议型 号:T12745L产 地:中国大陆
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T12745RO5263397;化合物RO5263397RO5263397
RO5263397 is a TAAR1 specific agonist with oral activity that has been used in antidepressant studies. It has also been found to act as an inhibitor of the enzyme cyclooxygenase-2 (COX-2), which is involved in the synthesis of prostaglandins.
价 格:¥电议型 号:T12745产 地:中国大陆
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T12744RO5256390;化合物 RO5256390RO5256390
RO5256390 is a trace amine-associated receptor 1 (TAAR1) agonist, a highly conserved G-protein-coupled receptor that blocks psychostimulant-induced hyperarousal, and may be used in the study of neurological disorders.
价 格:¥电议型 号:T12744产 地:中国大陆
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T12743RO-7;化合物 T12743RO-7
RO-7 is a next-generation polymerase (PA) endonuclease influenza A and B viruses inhibitor.
价 格:¥电议型 号:T12743产 地:中国大陆
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T12742Ro 20-0657/000;化合物 T12742Ro 20-0657/000
Ro 20-0657/000 is a Trimethoprim metabolite. Trimethoprim is an inhibitor of dihydrofolate reductase, used as an antibacterial agent in human and veterinary medicine.
价 格:¥电议型 号:T12742产 地:中国大陆
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T12741Ro-15-2041;化合物 T12741Ro-15-2041
Ro 15-2041 is a selective inhibitor of platelet phosphodiesterase, with antithrombotic properties.
价 格:¥电议型 号:T12741产 地:中国大陆
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T127402Coenzyme Q0;化合物 STOCK1N-17426CoQ0;CoQ0
Coenzyme Q0 (CoQ0), a potent, orally active ubiquinone compound derived from Antrodia cinnamomea, induces apoptosis and autophagy. It suppresses HER-2/AKT/mTOR signaling, enhancing apoptosis and autophagy mechanisms. Additionally, Coenzyme Q0 regulates NFκB/AP-1 activation and promotes Nrf2 stabilization, contributing to the attenuation of inflammation and redox imbalance. It also exhibits anti-angiogenic activity by downregulating MMP-9/NF-κB and upregulating HO-1 signaling.
价 格:¥电议型 号:T127402产 地:中国大陆
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T12740RMI 10874;化合物 T12740RMI 10874
RMI 10874 is a tilorone analogue. Tilorone is an orally bioavailable antiviral agent.
价 格:¥电议型 号:T12740产 地:中国大陆
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T1274Benzbromarone;苯溴马隆Desuric|||Normurat|||Urinorm;Desuric|||Normurat|||苯溴马隆|||Urinorm
Benzbromarone (Desuric) is a CYP2C9 inhibitor with Ki value of 19.3 nM.
价 格:¥电议型 号:T1274产 地:中国大陆
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T12739Rivanicline oxalate;化合物 T12739RJR-2403 oxalate|||(E)-Metanicotine oxalate;RJR-2403 oxalate|||(E)-Met
Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).
价 格:¥电议型 号:T12739产 地:中国大陆
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T12738L1Rivanicline 2HCl;(E)-位变异烟碱盐酸盐Rivanicline 2HCl(15585-43-0 Free base);Rivanicline 2HCl(15585-43-0 Free
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
价 格:¥电议型 号:T12738L1产 地:中国大陆
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T12738LRivanicline;化合物 T12738LRJR-2403|||(E)-Metanicotine;RJR-2403|||(E)-Metanicotine
Rivanicline is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki=26 nM). It show > 1,000 fold selectivity than α7 receptors(Ki= 36000 nM and IC50 : 26 nM).
价 格:¥电议型 号:T12738L产 地:中国大陆
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T12738Rivanicline hemioxalate;化合物 T12738RJR-2403 hemioxalate|||(E)-Metanicotine hemioxalate;RJR-2403 hemio
Rivanicline hemioxalate, also known as RJR-2403 hemioxalate or (E)-Metanicotine hemioxalate, is a chemical compound acting as a neuronal nicotinic receptor agonist with pronounced selectivity for the α4β2 receptor subtype, showing over 1,000-fold greater selectivity for this subtype (Ki=26 nM) compared to α7 receptors (Ki=3.6 μM). Its in vitro studies demonstrate no significant activation of nAChRs in PC12 cells, muscle type nAChRs, or muscarinic receptors at concentrations up to 1 mM. Furthermo
价 格:¥电议型 号:T12738产 地:中国大陆