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T25865NG-Nitroarginine methyl esterω-Nitroarginine methyl;L-NAME
NG-Nitroarginine methyl ester is a non-selective nitric oxide synthase inhibitor. It has been utilized experimentally to induce hypertension.
价 格:¥电议型 号:T25865产 地:中国大陆
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T2586Cabozantinib卡博替尼;XL184;BMS-907351
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).
价 格:¥电议型 号:T2586产 地:中国大陆
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T2585Bedaquiline贝达喹啉;TMC207;R207910
Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
价 格:¥电议型 号:T2585产 地:中国大陆
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T2583Cilastatin西司他丁;MK0791
Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to incr
价 格:¥电议型 号:T2583产 地:中国大陆
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T25821ML359ML 359;ML-359
ML359 is a protein disulfide isomerase inhibitor.
价 格:¥电议型 号:T25821产 地:中国大陆
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T25817Mitonafide米托萘胺;NSC-300288;NSC 300288;NSC300288
Mitonafide suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.
价 格:¥电议型 号:T25817产 地:中国大陆
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T2580Formoterol-1Arformoterol;Formoterol;福美特罗
Arformoterol is an adrenergic β-2 receptor agonist with a prolonged duration of action. It is used to manage asthma and in the treatment of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T2580产 地:中国大陆
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T2576Brivanib (alaninate)丙氨酸布立尼布;BMS-582664;Brivanib Alaninate
Brivanib Alaninate is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively
价 格:¥电议型 号:T2576产 地:中国大陆
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T2558CladribineCldAdo;2-Chloro-2′-deoxyadenosine;2-chlorodeoxyadenosine;2CdA;克拉屈滨
Cladribine, an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.
价 格:¥电议型 号:T2558产 地:中国大陆
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T2543Cabazitaxel卡巴他塞;TXD 258;taxoid XRP6258;RPR-116258A;XRP6258
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.
价 格:¥电议型 号:T2543产 地:中国大陆
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T25399ETP-45658ETP 45658;ETP45658
ETP 45658 is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively).
价 格:¥电议型 号:T25399产 地:中国大陆
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T2511Plinabulin普那布林;NPI-2358
Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule d
价 格:¥电议型 号:T2511产 地:中国大陆
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T2458CID755673
CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, CAK, and PKC isoforms.
价 格:¥电议型 号:T2458产 地:中国大陆
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T2383Panobinostat帕比司他;NVP-LBH589;LBH589
Panobinostat is a potent inhibitor of all HDACs (Kis: 0.6-31 nM for HDAC1-11).
价 格:¥电议型 号:T2383产 地:中国大陆
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T23358Sitagliptin phosphateJanuvia;Sitagliptin (phosphate);MK-0431 phosphate;磷酸西他列汀
Sitagliptin phosphate is a dipeptidyl peptidase-4 (DPP4) inhibitor.
价 格:¥电议型 号:T23358产 地:中国大陆
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T23333SC-581251-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑;SC 58125
SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor, with an IC50 of 0.04 μM. SC-58125 exhibits antitumor activity in vitro and in vivo, and it also can inhibit edema at the inflammatory site and is analgesic
价 格:¥电议型 号:T23333产 地:中国大陆
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T23077LNovokinin acetateNovokinin acetate (358738-77-9 free base)
Novokinin acetate exhibited an affinity for the AT2 receptor with Ki of 7 nM, and its antihypertensive and vasorelaxing activities were blocked by PD123319, an AT2 receptor antagonist.
价 格:¥电议型 号:T23077L产 地:中国大陆
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T22936Idalopirdine HydrochlorideLu AE58054盐酸盐;Idalopirdine HCl;Lu AE58054 Hydrochloride
Lu AE58054 hydrochloride is an in-vivo binding affinity and effect, in-vitro selectivity and potency of 5-HT(6)R antagonist (Ki: 0.83 nM).
价 格:¥电议型 号:T22936产 地:中国大陆
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T22904L-745870 trihydrochlorideL-745870三盐酸盐;L-745,870 trihydrochloride
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. L-745870 trihydrochloride exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors and shows weaker affinity for D2 and D3 receptors.
价 格:¥电议型 号:T22904产 地:中国大陆
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T22583Arcaine sulfate
Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine, is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor. Arcaine, an agmatine analog, along with ifenprodil, might have a possibility for therapeutic management
价 格:¥电议型 号:T22583产 地:中国大陆