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T4023L-Argininamide dihydrochloride；L-精氨酰胺二盐酸盐H-Arg-NH2.2HCl；L-精氨酰胺二盐酸盐|||H-Arg-NH2.2HCl
L-Argininamide dihydrochloride (H-Arg-NH2.2HCl) is used as a model compound in studies of the physicochemical characteristic of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.
价 格：￥电议型 号：T4023产 地：中国大陆
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T40111LBMS-1166-N-piperidine-CO-N-piperazine dihydrochloride；化合物T40111LBMS-1166-N-piperidine-CO-N-piperazin
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction with an IC50 of 39.2 nM.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride contains the target protein PD-1/PD-L1 ligand and PROTAC linker.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride can be used to synthesize PROTAC linker. BMS-1166-N-piperidine-CO-N-piperazine dihydro
价 格：￥电议型 号：T40111L产 地：中国大陆
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T39986LOX-IN-3 dihydrochloride；化合物LOX-IN-3 dihydrochlorideLOX-IN-3 dihydrochloride
LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50<10 μM) and human LOXL2 (IC50<1 μM)activities.
价 格：￥电议型 号：T39986产 地：中国大陆
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T39874GSK143 dihydrochloride；GSK143 dihydrochlorideGSK143 dihydrochloride
GSK143 dihydrochloride is a highly selective, orally active inhibitor of spleen tyrosine kinase (SYK), exhibiting a pIC 50 value of 7.5. It effectively inhibits phosphorylated Erk (pErk) with a pIC 50 value of 7.1. The compound demonstrates anti-inflammatory properties and hinders the recruitment of immune cells in the intestinal muscularis of mice.
价 格：￥电议型 号：T39874产 地：中国大陆
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T39872(S,R,S)-AHPC-C6-NH2 dihydrochloride；(S,R,S)-AHPC-C6-NH2 dihydrochloride(S,R,S)-AHPC-C6-NH2 dihydroch
(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along with a linker, which is used for the degradation of AKT PROTAC.
价 格：￥电议型 号：T39872产 地：中国大陆
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T39871(S,R,S)-AHPC-C2-NH2 dihydrochloride；(S,R,S)-AHPC-C2-NH2 dihydrochloride(S,R,S)-AHPC-C2-NH2 dihydroch
(S,R,S)-AHPC-C2-NH2 dihydrochloride is a combination of a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. It enables the synthesis of various PROTACs.
价 格：￥电议型 号：T39871产 地：中国大陆
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T39548Amustaline dihydrochloride；Amustaline dihydrochlorideS-303 dihydrochloride；S-303 dihydrochloride
Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key elements: an acridine anchor (a non-covalently bonding intercalator targeting nucleic acids), an effector (a bis-alkylator group that interacts with nucleophiles), and a linker (a flexible carbon chain with a labile ester bond, hydrolyzing at neutral pH to non-reactive products).
价 格：￥电议型 号：T39548产 地：中国大陆
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T39544IPN60090 dihydrochlorideIPN60090 dihydrochlorideIPN60090 dihydrochloride
IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-60090 dihydrochloride possesses outstanding physicochemical properties and pharmacokinetic characteristics in vivo. Therefore, it is a valuable compound for researching solid tumors, including lung and ovarian cancers.
价 格：￥电议型 号：T39544产 地：中国大陆
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T39481NVP-DPP728 dihydrochloride；NVP-DPP728 dihydrochlorideNVP-DPP728 dihydrochloride；NVP-DPP728 dihydroch
NVP-DPP728 dihydrochloride is a highly potent, selective, and orally active inhibitor of dipeptidyl peptidase IV (DPP-IV), with a binding affinity (K i ) of 11 nM. This compound proves useful for investigating diabetes mellitus in research studies.
价 格：￥电议型 号：T39481产 地：中国大陆
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T39411ACAT-IN-10 dihydrochloride；ACAT-IN-10 dihydrochlorideACAT-IN-10 dihydrochloride
ACAT-IN-10 dihydrochloride is a compound that serves as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT).ACAT-IN-10 dihydrochloride effectively hampers NF-κB mediated transcription, albeit to a lesser extent.
价 格：￥电议型 号：T39411产 地：中国大陆
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T39387Xanthine amine congener dihydrochloride；Xanthine amine congener dihydrochlorideXAC dihydrochloride||
Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as a convulsant agent in mouse models.
价 格：￥电议型 号：T39387产 地：中国大陆
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T3937Methyl L-histidinate dihydrochloride；L-组氨酸甲酯二盐酸盐L-Histidine methyl ester dihydrochloride；L-Histidine
The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production with activty value of 1.8 μM
价 格：￥电议型 号：T3937产 地：中国大陆
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T39199ML 120B dihydrochlorideML 120B dihydrochlorideML120B dihydrochloride
MLN120B dihydrochloride (ML120B dihydrochloride) is a highly potent, orally active inhibitor of IKKβ. It competitively binds to ATP and exhibits an impressive IC50 value of 60 nM. This compound effectively suppresses the growth of multiple myeloma cells both in vitro and in vivo. Furthermore, MLN120B dihydrochloride is valuable in the field of rheumatoid arthritis research.
价 格：￥电议型 号：T39199产 地：中国大陆
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T39195YM-244769 dihydrochloride化合物YM-244769 dihydrochlorideNCX3|||inhibit|||Na+/Ca2+ exchange
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys.
价 格：￥电议型 号：T39195产 地：中国大陆
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T39194PLX647 dihydrochloride；PLX647 dihydrochloridePLX647 dihydrochloride
PLX647 dihydrochloride is a potent and selective dual inhibitor of FMS and KIT kinases, with IC50 values of 28 nM and 16 nM, respectively. At a concentration of 1 μM, PLX647 dihydrochloride demonstrates superior selectivity against a wide range of 400 kinases, except FLT3 and KDR, where IC50 values are 91 nM and 130 nM, respectively. This orally active compound holds great potential for targeted kinase inhibition.
价 格：￥电议型 号：T39194产 地：中国大陆
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T39054Furosine dihydrochloride；Furosine dihydrochlorideFurosine dihydrochloride
Furosine dihydrochloride, an amino acid derivative, is a significant biochemical indicator of initial Maillard reactions. The compound is strongly associated with various diseases, including diabetes.
价 格：￥电议型 号：T39054产 地：中国大陆
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T38975WAY-100135 dihydrochloride；WAY-100135 dihydrochlorideWAY-100135 dihydrochloride
WAY-100135 dihydrochloride is a potent and selective antagonist of both presynaptic and postsynaptic 5-HT 1A receptors, exhibiting an IC 50 value of 34 nM specifically at the rat hippocampal 5-HT 1A receptor. This compound displays promising antipsychotic effects.
价 格：￥电议型 号：T38975产 地：中国大陆
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T38959BMS-604992 dihydrochlorideBMS-604992 dihydrochlorideEX-1314 dihydrochloride|||BMS-604992 dihydrochlo
BMS-604992 (EX-1314) dihydrochloride is a selective and orally active small-molecule agonist of the growth hormone secretagogue receptor (GHSR). It exhibits high-affinity binding (k i = 2.3 nM) and potent functional activity (EC 50 = 0.4 nM). Furthermore, BMS-604992 dihydrochloride has been shown to stimulate food intake in rodents.
价 格：￥电议型 号：T38959产 地：中国大陆
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T38601GYKI-47261 dihydrochloride；GYKI-47261 dihydrochlorideGYKI-47261 dihydrochloride
GYKI-47261 dihydrochloride is a selective AMPA receptor antagonist, administered orally, and exhibits competitive activity with an IC 50 of 2.5 μM. It displays a wide range of anticonvulsive effects and demonstrates neuroprotective properties. Additionally, GYKI-47261 dihydrochloride is a potent inducer of CYP2E1.
价 格：￥电议型 号：T38601产 地：中国大陆
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T38393Ipatasertib-NH2 dihydrochloride；Ipatasertib-NH2 dihydrochlorideRG7440-NH2 dihydrochloride|||Ipataser
Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquitin ligase.
价 格：￥电议型 号：T38393产 地：中国大陆
