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产品数:86101
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T8873BractoppinDNA break,Bractoppin,phosphopeptide,inhibit,DNA/RNA Synthesis,DNA damage,RAD51,G2 arrest,I
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activity exploration suggests that Bractoppin engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket that is distinct in structurally related BRCT domains, conferring selectivity.
价 格:¥电议型 号:T8873产 地:中国大陆
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T8132Iron sucroseIron sucrose,H2O2,pregnancy,ascorbate,Reactive Oxygen Species,IDA,Intravenous,ICAM-1,inh
Iron sucrose is treatment of iron deficiency anemia.
价 格:¥电议型 号:T8132产 地:中国大陆
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T7682Asymmetric dimethylarginineInhibitor,Endogenous Metabolite,NOS,NO Synthase,Asymmetric dimethylargini
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
价 格:¥电议型 号:T7682产 地:中国大陆
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TP1035LCyclic somatostatin Acetate(38916-34-6(free base))Cyclic somatostatin Acetate(38916346(free base)),C
Cyclic somatostatin Acetate is a cyclic tetradecapeptide regulating many endocrine and nervous system functions.
价 格:¥电议型 号:TP1035L产 地:中国大陆
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TN1968N-?Feruloyloctopaminecarcinoma,N-?Feruloyloctopamine,inhibit,Protein kinase B,MAPK,PKB,Inhibitor,Hep
N-Feruloyloctopamine is a natural product.
价 格:¥电议型 号:TN1968产 地:中国大陆
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TP1290GRGDSP acetate(91037-75-1 free base)GRGDSP acetate(91037 75 1 free base),GRGDSP acetate(91037751 fre
GRGDSP acetate is a synthetic linear RGD peptide and is an integrin inhibitor.
价 格:¥电议型 号:TP1290产 地:中国大陆
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T9683VX-150Na+ channels,VX-150,indications,Inhibitor,Na channels,orally,inhibit,pain,VX 150,VX150,Sodium
VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).
价 格:¥电议型 号:T9683产 地:中国大陆
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TN7050Potassium 7-hydroxy-1-naphthalenesulfonaPotassium 7 hydroxy 1 naphthalenesulfona,Potassium 7hydroxy1
Potassium 7-hydroxy-1-naphthalenesulfona is naturally present in the fruit of the Rubiaceae gardenia, the flowers of the Iridaceae crocus, and the flowers and leaves of the Scrophulariaceae Scrophulariaceae.
价 格:¥电议型 号:TN7050产 地:中国大陆
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TP1434LLecirelin acetate(61012-19-9 free base)Lecirelin acetate(61012199 free base),Lecirelin acetate(61012
Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts.
价 格:¥电议型 号:TP1434L产 地:中国大陆
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T6571Lomerizine dihydrochlorideCa2+ channels,Ca channels,inhibit,Lomerizine,KB 2796,KB2796,Lomerizine dih
Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
价 格:¥电议型 号:T6571产 地:中国大陆
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TN1922Meranzin hydrateMeranzin hydrate,Meranzin,inhibit,Inhibitor
Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; it produces a rapid effect mediated by AMPA receptors and involving BDNF modulation through the ERK1/2 pathway.
价 格:¥电议型 号:TN1922产 地:中国大陆
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T7158OmbitasvirABT267,Hepatitis C virus,Inhibitor,inhibit,HCV,Ombitasvir,ABT 267
Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a
价 格:¥电议型 号:T7158产 地:中国大陆
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T9292ALE-0540
ALE-0540 is a nonpeptidic heterocyclic molecule that inhibits the binding of NGF to p75 and TrkA, as well as signal transduction and biological responses mediated by TrkA receptors.
价 格:¥电议型 号:T9292产 地:中国大陆
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TP1724LPUMA BH3 acetatePUMA BH-3 acetate,PUMA BH3 acetate
PUMA BH3 acetate is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of 26 nM.
价 格:¥电议型 号:TP1724L产 地:中国大陆
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T80324-Pentenoic acidEndogenous Metabolite,inhibit,4 Pentenoic acid,4Pentenoic acid,4-Pentenoic acid,Inhi
4-Pentenoic acid, also known as allyl acetic acid or 4-pentenate, belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain. 4-Pentenoic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
价 格:¥电议型 号:T8032产 地:中国大陆
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T9221UNC926 hydrochlorideUNC926,methyl-lysine,L3MBTL3,Epigenetic Reader Domain,UNC-926 hydrochloride,UNC9
UNC926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor.
价 格:¥电议型 号:T9221产 地:中国大陆
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TN2081Maohuoside Aorally,MAPK,osteogenesis,Maohuoside A,inhibit,Transforming growth factor beta receptors,
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
价 格:¥电议型 号:TN2081产 地:中国大陆
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T7847Apelin-13 triTFA(217082-58-1(free base))Apelin 13 triTFA(217082 58 1(free base)),Apelin13 triTFA(217
Apelin-13 triTFA is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM.
价 格:¥电议型 号:T7847产 地:中国大陆
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T7959(+)-ISOPINOCAMPHEOL(+) ISOPINOCAMPHEOL,(+)ISOPINOCAMPHEOL
(+)-ISOPINOCAMPHEOL is a natural product.
价 格:¥电议型 号:T7959产 地:中国大陆
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T88684BP-TQS4BP TQS,allosteric agonist,transmembrane site,Inhibitor,α7 nAChR,inhibit,Nicotinic acetylchol
4BP-TQS is an allosteric agonist of α7 nAChRs.
价 格:¥电议型 号:T8868产 地:中国大陆