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T6705TIC10 IsomerTIC-10 Isomer,Inhibitor,inhibit,TIC10 Isomer
TIC10 Isomer is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格:¥电议型 号:T6705产 地:中国大陆
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TP2206[Leu31,Pro34]-Neuropeptide Y (porcine)Inhibitor,Neuropeptide Y Receptor,anxiolytic,NPY,[Leu31,Pro34]
[Leu31,Pro34]-Neuropeptide Y (porcine), is a selective and high affinity agonist of neuropeptide Y (NPY) Y1 receptor with anxiolytic effects.
价 格:¥电议型 号:TP2206产 地:中国大陆
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T8044Ajmalicine
Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, IC50 = 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity。
价 格:¥电议型 号:T8044产 地:中国大陆
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T2344LY 344864migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-3
LY344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
价 格:¥电议型 号:T2344产 地:中国大陆
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T6953Prilocainelocal,anaesthetize,inhibit,Inhibitor,Sodium potassium pump,Na(+),K(+),neurotoxic,Na+/K+ AT
Prilocaine is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.
价 格:¥电议型 号:T6953产 地:中国大陆
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T6548IrsogladinePhosphodiesterase (PDE),mAChR,inhibit,Irsogladine,Muscarinic acetylcholine receptor,Inhib
Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.
价 格:¥电议型 号:T6548产 地:中国大陆
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TQ0046BavisantJNJ31001074,JNJ 31001074,Neurological disorders,inhibit,Histamine Receptor,attention-deficit
Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
价 格:¥电议型 号:TQ0046产 地:中国大陆
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T6512G-418 disulfatesynthesis,eukaryotic,Antibiotic G-418,G-418 disulfate,Antibiotic G 418,Antibiotic G41
G-418 (disulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
价 格:¥电议型 号:T6512产 地:中国大陆
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T9521CHR-6494 TFACHR-6494,inhibit,apoptosis,Haspin Kinase,NRAS mutant melanoma cells,CHR 6494,mitotic cat
CHR-6494 TFA is a potent haspin inhibitor, with an?IC50?of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the?apoptosis?of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer
价 格:¥电议型 号:T9521产 地:中国大陆
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T7370TalarozoleRetinoid X receptors,R 115866,Retinoic acid receptors,RAR/RXR,inhibit,Talarozole,Cytochrom
Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of acne, psoriasis and other keratinization disorders.
价 格:¥电议型 号:T7370产 地:中国大陆
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T8822JNJ-5207852 dihydrochlorideInhibitor,toxicity,JNJ5207852,inhibit,low,JNJ 5207852,sleep,REM,JNJ-52078
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor.
价 格:¥电议型 号:T8822产 地:中国大陆
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T8158Tilianinantioxidant,Inhibitor,inflammatory,myocardial-protective,diabetic,hyperlipidemic,inhibit,Til
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.
价 格:¥电议型 号:T8158产 地:中国大陆
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TN1373α-Humuleneα Humulene,Inhibitor,α-Humulene,Humulene,NOS,αHumulene,inhibit,COX,Nitric oxide synthases,
α-Humulene is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression.
价 格:¥电议型 号:TN1373产 地:中国大陆
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TN3575(±)-CannabichromeneInhibitor,(±)-Cannabichromene,(±)Cannabichromene,(±) Cannabichromene,DL-cannabich
Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hypermotility in vivo in a manner that is not dependent on cannabinoid receptors or TRPA1.
价 格:¥电议型 号:TN3575产 地:中国大陆
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T7196HG-10-102-01Parkinson’s disease,Leucine-rich repeat kinase 2,inhibit,Ser910,BBB,HG 10 102 01,Radiosy
HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).
价 格:¥电议型 号:T7196产 地:中国大陆
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TN1739Homodihydrocapsaicin Iphytotoxic,Capsicum annuum,Capsaicinoid,Homodihydrocapsaicin I,Inhibitor,inhib
Homodihydrocapsaicin I is a natural product from Capsicum annuum L.
价 格:¥电议型 号:TN1739产 地:中国大陆
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T7045ClonidineClonidine,α2-adrenergic,inhibit,Inhibitor,anesthesia,Adrenergic Receptor,Beta Receptor
Clonidine is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many years, clonidine has not been linked definitively to either serum aminotransferase elevations or clinically apparent liver injury.
价 格:¥电议型 号:T7045产 地:中国大陆
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T9681MAK-683 hydrochlorideEED inhibitor,MAK 683 hyrochloride,embryonic ectoderm development,Histone Methy
MAK683 hydrochloride is an inhibitor of embryonic ectoderm development (EED) (patent US20160176882 A1, compound example 2). MAK683 exhibits IC50s of 59, 26, 89 nM in EED Alphascreen binding, ELISA and LC-MS assay.
价 格:¥电议型 号:T9681产 地:中国大陆
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T8901YUM70Heat shock proteins,YUM70,HSP,cancer,pancreatic,reticulum,Apoptosis,GRP78,YUM-70,stress-mediate
YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
价 格:¥电议型 号:T8901产 地:中国大陆
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T7555Piperidolate hydrochlorideInhibitor,Piperidolate,inhibit,Muscarinic acetylcholine receptor,Piperidol
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs).
价 格:¥电议型 号:T7555产 地:中国大陆