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T78633MeOSuc-AAPV-CMK;化合物 MeOSuc-AAPV-CMKElastase Inhibitor III;Elastase Inhibitor III
MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated cleavage of adiponectin [1].
价 格:¥电议型 号:T78633产 地:中国大陆
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T78578GSK-3 Inhibitor XIII;GSK-3抑制剂XIIIGSK-3 Inhibitor XIII
GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.
价 格:¥电议型 号:T78578产 地:中国大陆
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T78430Bacterial Sortase Substrate III, Abz/DNP TFA;化合物 Bacterial Sortase Substrate III, Abz/DNP TFABacteri
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide used to monitor the activity of the Staphylococcus aureus transpeptidase sortase A (SrtA). This enzyme catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges by cleaving its native substrate, Bacterial Sortase Substrate III, Abz/DNP. The cleavage event can be detected with excitation/emission wavelengths of Ex/Em=320 nm/420 nm.
价 格:¥电议型 号:T78430产 地:中国大陆
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T78329Litifilimab;化合物 LitifilimabBIIB059;BIIB059
Litifilimab, a humanized IgG1-κ antibody, targets the C-type lectin domain family 4 member C (CLEC4C) and has potential applications in the study of cutaneous lupus erythematosus (CLE) [1] [2].
价 格:¥电议型 号:T78329产 地:中国大陆
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T78108?-Conotoxin-CnIIIC acetate;芋螺肽醋酸盐?-Conotoxin-CnIIIC acetate
?-Conotoxin-CnIIIC acetate is a potent NaV1.4 sodium channel antagonist, a conotoxin peptide consisting of 22 amino acids, used for muscle relaxation and pain relief.
价 格:¥电议型 号:T78108产 地:中国大陆
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T78060ProTx II TFA;化合物 ProTx II TFAProTx II TFA
ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over other sodium channel subtypes. It decreases channel conductance, shifts activation towards more positive potentials, and inhibits action potential propagation in nociceptors [1] [2].
价 格:¥电议型 号:T78060产 地:中国大陆
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T77650Topoisomerase II inhibitor 14;拓扑异构酶II抑制剂14Topoisomerase II inhibitor 14
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis and blocks the cell cycle in S phase.Topoisomerase II inhibitor 14 reduces the amount of GSH, MDA and NO. Topoisomerase II inhibitor 14 reduces the amount of GSH, MDA and NO.
价 格:¥电议型 号:T77650产 地:中国大陆
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T77628Bisindolylmaleimide III;双辛基马来酰亚胺IIIBisindolylmaleimide III
Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.
价 格:¥电议型 号:T77628产 地:中国大陆
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T77416Opicinumab;奥匹努单抗BIIB033;BIIB033
Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis.
价 格:¥电议型 号:T77416产 地:中国大陆
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T77288KKII5;4,6-二苯基-1,2,3,4-四氰嘧啶-2-硫KKII5
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons.
价 格:¥电议型 号:T77288产 地:中国大陆
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T77042Aducanumab;阿杜那单抗BIIB037;BIIB037
Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer´s disease (AD).
价 格:¥电议型 号:T77042产 地:中国大陆
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T76861Cinpanemab;辛帕奈单抗BIIB054;BIIB054
Cinpanemab (BIIB054) is a novel human monoclonal antibody with affinity for alpha-synuclein residues 1-10. Cinpanemab can be used to study Parkinson´s disease and related diseases.
价 格:¥电议型 号:T76861产 地:中国大陆
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T7680GSNKGAIIGLM(131602-53-4(free base));BETA-淀粉样蛋白片断25-35Amyloid beta-peptide(25-35);Amyloid beta-peptid
GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer´s amyloid β-peptide.
价 格:¥电议型 号:T7680产 地:中国大陆
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T7677JNK Inhibitor VIII;化合物JNK Inhibitor VIIITCS JNK 6o;TCS JNK 6o
JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).
价 格:¥电议型 号:T7677产 地:中国大陆
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T76654Polyphemusin II-Derived Peptide;化合物 Polyphemusin II-Derived PeptidePolyphemusin II-Derived Peptide
Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, effectively inhibits HIV-1 entry and disrupts the binding of the anti-CXCR4 monoclonal antibody (12G5) to CXCR4 [1].
价 格:¥电议型 号:T76654产 地:中国大陆
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T76634(Sar1,Ile4,8)-Angiotensin II;化合物 (Sar1,Ile4,8)-Angiotensin II(Sar1,Ile4,8)-Angiotensin II
(Sar1,Ile4,8)-Angiotensin II is a functionally selective agonist for the angiotensin II type 1 receptor (AT1R), enhancing insulin-stimulated signaling of the insulin receptor (IR) and glycogen synthesis. It boosts the insulin-induced phosphorylation of Akt and GSK3α/β [1].
价 格:¥电议型 号:T76634产 地:中国大陆
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T76547vMIP-II (1-21);化合物 vMIP-II (1-21)vMIP-II (1-21)
vMIP-II (1-21), a CXCR4 antagonist, exhibits broad-spectrum interaction with both CC and CXC chemokine receptors, specifically binding to CXCR4. It competes for CXCR4 binding of 125I-SDF-1R with an IC 50 value of 190 nM [1].
价 格:¥电议型 号:T76547产 地:中国大陆
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T76539Insulin-like growth factor II;化合物 Insulin-like growth factor IIInsulin-like growth factor II
Insulin-like Growth Factor II (IGF-2), the primary somatomedin in human serum, exerts both permissive and direct influences on neurite outgrowth and significantly improves the survival of sympathetic and sensory neurons [1] [2].
价 格:¥电议型 号:T76539产 地:中国大陆
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T76475Casein Kinase II Substrate;化合物 Casein Kinase II SubstrateCasein Kinase II Substrate
Casein Kinase II Substrate, a peptide substrate, is selectively phosphorylated by casein kinase II (CK2) [1].
价 格:¥电议型 号:T76475产 地:中国大陆
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T76391p60c-src substrate II;化合物 p60c-src substrate IIp60c-src substrate II
P60c-src substrate II is a potent pentapeptide substrate for the tyrosine kinase pp60c-src [1].
价 格:¥电议型 号:T76391产 地:中国大陆