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T755604(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-;化合物 4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-
4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2), a quinolone alkaloid extracted from Cnidium, demonstrates activity against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting minimum inhibitory concentration (MIC) values of 32 μg/mL (ATCC 33591) and 16 μM/mL (ATCC 25923) respectively [1].
价 格:¥电议型 号:T75560产 地:中国大陆
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T755071-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone;化合物 1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone1-M
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone exhibits strong antibacterial properties, demonstrating an MIC 50 of 22 ?M and an MIC 90 of 50 ?M against Helicobacter pylori Strain 51. This compound shows promise for research into gastric and duodenal ulcers [1].
价 格:¥电议型 号:T75507产 地:中国大陆
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T75402,5-Di-tert-butylhydroquinone2,5-二特丁基对苯二酚BHQ|||2,5-二特丁基对苯二酚
2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.
价 格:¥电议型 号:T7540产 地:中国大陆
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T75333Quinine hemisulfate hydrate;化合物 Quinine hemisulfate hydrateQuinine hemisulfate hydrate
Quinine hemisulfate hydrate, an alkaloid extracted from the cinchona tree bark, serves as an anti-malarial agent and potassium channel inhibitor. It specifically targets and inhibits WT mouse Slo3 (K Ca 5.1) channel currents induced by voltage pulses to +100?mV, having an IC 50 value of 169 μM [1] [2].
价 格:¥电议型 号:T75333产 地:中国大陆
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T753327-Hydroxy-4-methyl-2(1H)-quinolone;化合物 7-Hydroxy-4-methyl-2(1H)-quinolone7-Hydroxy-4-methyl-2(1H)-qu
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. For preservation, it should be protected from light.
价 格:¥电议型 号:T75332产 地:中国大陆
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T7532Piperaquine;磷酸哌喹Piperaquine
Piperaquine is a bis-quinoline compound that inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.
价 格:¥电议型 号:T7532产 地:中国大陆
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T75275Quinupristin mesylate;化合物 Quinupristin mesylateQuinupristin mesylate
Quinupristin mesylate, a streptogramin antibiotic, inhibits peptide bond formation, thereby halting the extension of polypeptide chains and facilitating the release of incomplete protein chains from bacterial ribosomal subunits [1] [2].
价 格:¥电议型 号:T75275产 地:中国大陆
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T75259Baquiloprim;化合物 BaquiloprimBaquiloprim
Baquiloprim, an antibiotic, functions as a selective inhibitor of bacterial dihydrofolate reductases, exhibiting in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria [1] [2].
价 格:¥电议型 号:T75259产 地:中国大陆
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T75030Ubiquitination-IN-2;化合物 Ubiquitination-IN-2Ubiquitination-IN-2
Ubiquitination-IN-2 is a potent inhibitor of E1-E2 protein?protein interactions (PPI), displaying inhibitory activity with a dissociation constant (Kd) of 0.72 μM for the ubiquitin E1 (Uba1) enzyme. By blocking the transfer of ubiquitin from E1 to E2, Ubiquitination-IN-2 serves as a valuable tool in cancer research [1].
价 格:¥电议型 号:T75030产 地:中国大陆
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T74113Sesquicillin A;化合物 Sesquicillin ASesquicillin A
Sesquicillin A, an insecticidal antibiotic and fungal metabolite extracted from white plantain, exhibits potent growth inhibition against A. salina brine shrimp, demonstrating a minimum inhibitory concentration (MIC) value of 6.25 ?g/mL [1].
价 格:¥电议型 号:T74113产 地:中国大陆
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T73964Hydroxychloroquine Impurity F;化合物 Hydroxychloroquine Impurity FHydroxychloroquine Impurity F
Hydroxychloroquine Impurity F, an impurity in Hydroxychloroquine, is identified in the synthetic antimalarial agent known for its capability to inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Additionally, Hydroxychloroquine demonstrates effective inhibition of SARS-CoV-2 infection in vitro [1] [2] [3].
价 格:¥电议型 号:T73964产 地:中国大陆
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T73963Hydroxychloroquine Impurity E;化合物 Hydroxychloroquine Impurity EHydroxychloroquine Impurity E
Hydroxychloroquine Impurity E, an impurity found in Hydroxychloroquine, a synthetic antimalarial compound that also inhibits Toll-like receptor 7/9 (TLR7/9) signaling, has been shown to effectively inhibit SARS-CoV-2 infection in vitro [1] [2] [3].
价 格:¥电议型 号:T73963产 地:中国大陆
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T73845Piperaquine tetraphosphate;化合物 Piperaquine tetraphosphatePiperaquine tetraphosphate
Piperaquine tetraphosphate, a potent antimalarial agent, demonstrates inhibitory effects against both chloroquine-sensitive and chloroquine-resistant malaria isolates. When combined with dihydroartemisinin, it holds potential for researching chloroquine-resistant malaria [1] [2].
价 格:¥电议型 号:T73845产 地:中国大陆
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T73341Quipazine化合物 Quipazine2-(1-哌嗪基)喹啉
Quipazine, a 5-HT (serotonin) agonist, demonstrates affinity for the 5-HT3R receptor in rats with a Ki value of 1.4 nM, effectively displacing GR65630. It exhibits antiviral activity against SARS-CoV-2, achieving an EC50 of 31.64 μM. Additionally, Quipazine acts as a 5-HT3R agonist in peripheral models, indicating its potential for neurological disease research.
价 格:¥电议型 号:T73341产 地:中国大陆
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T7310Paquinimod;帕奎莫德ABR 25757;帕奎莫德|||ABR 25757
Paquinimod (ABR 25757) is a specific S100A8/S100A9 inhibitor with oral activity. Paquinimod has immunomodulatory activity and can be used for the treatment of systemic lupus erythematosus.
价 格:¥电议型 号:T7310产 地:中国大陆
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T72969Actinoquinol化合物 Actinoquinol阿克汀喹
Actinoquinol, a compound effective in absorbing UVB radiation, plays a crucial role in protecting the human eye from photooxidative and other oxidative processes.
价 格:¥电议型 号:T72969产 地:中国大陆
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T72735Coleon-U-quinone;化合物 Coleon-U-quinoneColeon-U-quinone
Coleon-U-quinone, a potent P-gp (P-glycoprotein) inhibitor, effectively reduces the viability of cancer cells and increases the sensitivity of multidrug-resistant cancer cells to Doxorubicin [1].
价 格:¥电议型 号:T72735产 地:中国大陆
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T72186Tariquidar dihydrochloride;化合物 Tariquidar dihydrochlorideXR9576 dihydrochloride;XR9576 dihydrochlori
Tariquidar dihydrochloride, also known as XR9576 dihydrochloride, is a potent, specific P-glycoprotein (P-gp) inhibitor exhibiting high affinity (Kd = 5.1 nM).
价 格:¥电议型 号:T72186产 地:中国大陆
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T72133Asterriquinol D dimethyl ether;化合物 Asterriquinol D dimethyl etherAsterriquinol D dimethyl ether
Asterriquinol D dimethyl ether, a fungal metabolite, inhibits mouse myeloma NS-1 cell lines, demonstrating an IC50 value of 28 μg/mL. Additionally, it also acts against Tritrichomonas foetus.
价 格:¥电议型 号:T72133产 地:中国大陆
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T72121Tetrahydroxyquinone monohydrate;化合物 Tetrahydroxyquinone monohydrateTetrahydroxybenzoquinone monohydr
Tetrahydroxyquinone monohydrate (Tetrahydroxy-1,4-benzoquinone monohydrate), serving as an early-stage anticataract agent, is a redox-active benzoquinone. This compound engages in redox cycling with semiquinone radicals, resulting in the generation of reactive oxygen species (ROS).
价 格:¥电议型 号:T72121产 地:中国大陆