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T13714LGRK2-IN-1 hydrochloride (2055990-90-2 free base);化合物 T13714LGRK2-IN-1 hydrochloride;GRK2-IN-1 hydroc
GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
价 格:¥电议型 号:T13714L产 地:中国大陆
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T13707Pareptide monohydrochloride;帕立太特盐酸盐Pareptide monohydrochloride
Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).
价 格:¥电议型 号:T13707产 地:中国大陆
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T13695LFmoc-1,6-diaminohexane hydrochloride;化合物Fmoc-1,6-diaminohexane hydrochlorideFmoc-1,6-diaminohexane h
Fmoc-1,6-diaminohexane hydrochloride is an analog of Osw-1 which has the potential for Alzheimer´s disease and cancer treatment.
价 格:¥电议型 号:T13695L产 地:中国大陆
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T13675Elacestrant dihydrochloride;化合物RAD1901 dihydrochlorideRAD1901 dihydrochloride;RAD1901 dihydrochlorid
Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM for ERβ, respectively.
价 格:¥电议型 号:T13675产 地:中国大陆
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T13671L(S,R,S)-AHPC-Me dihydrochloride;化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demonstrates potent degradation of BET protein in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound serves as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, that facilitates the recruitment of von Hippel-Lindau (VHL) prote
价 格:¥电议型 号:T13671L产 地:中国大陆
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T13671(S,R,S)-AHPC-Me hydrochloride;化合物(S,R,S)-AHPC-Me hydrochlorideVHL ligand 2 hydrochloride|||E3 ligase
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.
价 格:¥电议型 号:T13671产 地:中国大陆
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T13664DSP-4 hydrochloride;化合物DSP-4 hydrochlorideNeurotoxin DSP 4 (hydrochloride);Neurotoxin DSP 4 (hydroch
DSP-4 hydrochloride (Neurotoxin DSP 4 (hydrochloride)) (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats,
价 格:¥电议型 号:T13664产 地:中国大陆
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T13663-Pyridylacetic acid hydrochloride;吡啶-3-乙酸盐酸盐3-Pyridylacetic acid hydrochloride
3-Pyridylacetic acid hydrochloride (3-PAA-HCl) is a high homologue of niacin. It is a decomposition product of nicotine (and other tobacco alkaloids). It can also react with amines, alcohols and carboxylic acids, and can also act as an acid in the reaction. catalyst.
价 格:¥电议型 号:T1366产 地:中国大陆
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T13655DL-Norepinephrine hydrochloride;去甲肾上腺素盐酸盐Lys|||DL-lysine;去甲肾上腺素盐酸盐|||Lys|||DL-lysine
DL-Norepinephrine hydrochloride (DL-lysine) is a high-affinity basic amino acid substrate of amino acid transporter b0 + with a Km value in the range of 100-400 μM.
价 格:¥电议型 号:T13655产 地:中国大陆
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T13621CNDAC hydrochloride;化合物CNDAC hydrochlorideCNDAC hydrochloride
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
价 格:¥电议型 号:T13621产 地:中国大陆
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T13609Chlorazanil hydrochloride;氯拉扎尼盐酸盐Chlorazanil hydrochloride
Chlorazanil hydrochloride is the hydrochloride form of Chlorazanil.Chlorazanil, a triazine derivative, is an orally effective diuretic that blocks the absorption of sodium and chloride in the distal tubule.
价 格:¥电议型 号:T13609产 地:中国大陆
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T13586LBPK-29 hydrochloride;化合物BPK-29 hydrochlorideBPK-29 hydrochloride
BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274. It impairs the anchorage-independent growth of KEAP1-mutant cancer cells.
价 格:¥电议型 号:T13586L产 地:中国大陆
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T13585Bometolol Hydrochloride;波美洛尔盐酸盐Bometolol Hydrochloride
Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.
价 格:¥电议型 号:T13585产 地:中国大陆
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T13568LBCX 1470 hydrochloride;BCX 1470 盐酸盐BCX 1470 hydrochloride(217099-43-9 Free base)|||BCX1470 HCl;BCX 1
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.
价 格:¥电议型 号:T13568L产 地:中国大陆
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T13564LAZ7550 hydrochloride;化合物AZ7550 hydrochlorideAZ7550 hydrochloride (1421373-99-0 free base);AZ7550 hyd
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
价 格:¥电议型 号:T13564L产 地:中国大陆
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T13564-Hydroxy-3-methoxybenzylamine hydrochloride;香兰素胺盐酸盐N-Vanillylamine hydrochloride;香兰素胺盐酸盐|||N-Vanill
4-Hydroxy-3-methoxybenzylamine hydrochloride (N-Vanillylamine hydrochloride) is an alkaloid that is an intermediate in the biosynthesis of capsaicin. 4-Hydroxy-3-methoxybenzylamine hydrochloride is produced from vanillin by the enzyme vanillin aminotransferase.
价 格:¥电议型 号:T1356产 地:中国大陆
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T13480L(S)-(-)-5-Fluorowillardiine hydrochloride;化合物 T13480L(S)-5-Fluorowillardiine hydrochloride|||(5S)-Fl
(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific agonist of AMPAR.
价 格:¥电议型 号:T13480L产 地:中国大陆
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T13463(+)-Dihydrexidine hydrochloride;化合物 T13463(+)-DAR-0100 (hydrochloride);(+)-DAR-0100 (hydrochloride)
(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).
价 格:¥电议型 号:T13463产 地:中国大陆
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T13460(+)-Cevimeline hydrochloride hemihydrate;化合物 T13460(+)-AF102B hydrochloride hemihydrate|||(+)-SNI-20
(+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011), a potent muscarinic receptor agonist, stands as a promising therapeutic candidate for treating xerostomia in Sjogren´s syndrome. This compound has demonstrated a broad pharmacological profile across various systems including gastrointestinal, urinary, and reproductive, in animal models such as mice, rats, guinea pigs, rabbits, and dogs. Its metabolism was assessed in vitro using rat and dog liver microsomes, revealing that (+)-SNI-20
价 格:¥电议型 号:T13460产 地:中国大陆
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T1343LCrystal Violet结晶紫Methyl Violet 10B|||Hexamethylpararosaniline chloride|||氯化结晶紫|||Basic Violet 3|||结晶
Crystal Violet (Hexamethylpararosaniline chloride) is a triarylmethane dye that is a mixture of violet rosanilinis, with antibacterial, antifungal, and anthelmintic properties.
价 格:¥电议型 号:T1343L产 地:中国大陆