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T10298LAMG-548;化合物 T10298LAMG-548
AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM)[1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε[2].
价 格:¥电议型 号:T10298L产 地:中国大陆
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T10298AMG-548 hydrochloride (864249-60-5 free base);化合物 T10298AMG-548 hydrochloride;AMG-548 hydrochloride
AMG-548 hydrochloride is an orally active and selective p38α inhibitor (Ki: 0.5 nM) and shows slightly selective over p38β (Ki: 36 nM) and >1000 fold selective against p38γ/p38δ. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50: 3 nM).
价 格:¥电议型 号:T10298产 地:中国大陆
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T10297LAMG 487;化合物AMG 487AMG 487
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:中国大陆
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T10297AMG 487 (S-enantiomer);化合物 T10297AMG 487 (S-enantiomer)
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.
价 格:¥电议型 号:T10297产 地:中国大陆
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T10296Mavorixafor trihydrochloride;化合物 T10296AMD-070 trihydrochloride;AMD-070 trihydrochloride
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (IC50s: 1 and 9 nM).
价 格:¥电议型 号:T10296产 地:中国大陆
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T10295Amantanium bromide;金刚溴铵Amantanil bromidum;金刚溴铵|||Amantanil bromidum
Amantanium bromide (Amantanil bromidum) is a quaternary ammonium antibacterial/antifugal agent useful as a surgical antiseptic and for the topical therapy of mucous and cutaneous infections.
价 格:¥电议型 号:T10295产 地:中国大陆
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T10294AM9405;化合物 T10294AM9405
AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC 50 s of 45.71 and 0.076 nM, respectively. AM9405 significantly slowed mouse intestinal motility in physiological conditions. Moreover, AM9405 reversed hypermotility and reduced pain in mouse models mimicking symptoms of functional GI disorders, such as stress-induced diarrhea and writhing test.
价 格:¥电议型 号:T10294产 地:中国大陆
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T10292AM-6494;化合物 T10292AM-6494
AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).
价 格:¥电议型 号:T10292产 地:中国大陆
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T10291α-Truxillic acid;化合物 T10291α-Truxillic acid
α-Truxillic acid, known for its anti-inflammatory activities, is produced through the dimerization of two molecules of α-trans-cinnamic acid.
价 格:¥电议型 号:T10291产 地:中国大陆
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T10290LAlpertine HCl;阿尔哌汀盐酸盐Win 31665 HCl|||Alpertine HCl(27076-46-6 Free base);Win 31665 HCl|||Alpertine H
Alpertine HCl is a small molecule compound with anti-neuropathic properties.
价 格:¥电议型 号:T10290L产 地:中国大陆
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T10290Alpertine;化合物 T10290Win 31665;Win 31665
Alpertine is an antipsychotic agent.
价 格:¥电议型 号:T10290产 地:中国大陆
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T1029Aztreonam;氨曲南SQ-26,776;SQ-26,776|||氨曲南
Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.
价 格:¥电议型 号:T1029产 地:中国大陆
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T10229Acebutolol D7;化合物 T10229Acebutolol D7
Acebutolol D7 is a deuterium-labeled Acebutolol. Acebutolol is a selective antagonist of the β1 adrenergic receptor used in the treatment of angina pectoris, hypertension, and cardiac arrhythmias.
价 格:¥电议型 号:T10229产 地:中国大陆
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T10129(3S,5R)-Fluvastatin sodium;化合物 T10129(3S,5R)-XU 62-320;(3S,5R)-XU 62-320
(3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.
价 格:¥电议型 号:T10129产 地:中国大陆
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T100291-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine;L-α-磷脂酰胆碱-β-花生四烯酰-γ-硬脂酰1-Stearoyl-2-arachidono
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that has been found in the aging mouse brain.
价 格:¥电议型 号:T10029产 地:中国大陆
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T0966Sennoside A;番泻苷 ANSC 112929;番泻苷A|||NSC 112929|||番泻苷 A
Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
价 格:¥电议型 号:T0966产 地:中国大陆
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T0929Docusate sodium;多库脂钠Aerosol OT|||Dioctyl sulfosuccinate sodium salt|||Bis(2-ethylhexyl) sulfosuccina
Docusate sodium (Aerosol OT) is an orally available, over-the-counter laxative and stool softener used to treat or prevent constipation. Docusate has not been linked to serum enzyme elevations during therapy or to clinically apparent liver injury with jaundice.
价 格:¥电议型 号:T0929产 地:中国大陆
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T0829Etofylline;乙羟茶碱7-(β-Hydroxyethyl)theophylline|||Aethophyllinum|||7-Theophyllineethanol|||Oxyphylline
Etofylline (Oxyphylline) is used for difficulty in breathing, asthma, breathing difficulty and other conditions.
价 格:¥电议型 号:T0829产 地:中国大陆
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T0729Benzyl benzoate;苯甲酸苄酯Ascabiol|||Novoscabin|||Scabitox|||Benzoic acid benzyl ester;Ascabiol|||Novosca
Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (particularly at night), and may lead to a secondary infection. Benzyl benzoate is useful in the therapy of scabies because it is lethal to this mite. It is also used for the therapy of lice affection of the body and head. Benzyl benzoate is not the therapy of choice for scabies becaus
价 格:¥电议型 号:T0729产 地:中国大陆
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T0717LEnoxacin;依诺沙星NSC 629661|||AT 2266|||Pd107779|||CI 919;依诺沙星|||NSC 629661|||AT 2266|||Pd107779|||CI 91
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
价 格:¥电议型 号:T0717L产 地:中国大陆