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T131143Compound N105-0119；化合物 N105-0119Compound N105-0119
Compound N105-0119 is a useful organic compound for research related to life sciences and the catalog number is T131143.
价 格：￥电议型 号：T131143产 地：中国大陆
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T131142Compound N105-0131；化合物 N105-0131Compound N105-0131
Compound N105-0131 is a useful organic compound for research related to life sciences and the catalog number is T131142.
价 格：￥电议型 号：T131142产 地：中国大陆
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T1310589-Hydroxyhexylitaconic acid；化合物 9-Hydroxyhexylitaconic acid9-Hydroxyhexylitaconic acid
9-Hydroxyhexylitaconic acid is a useful organic compound for research related to life sciences and the catalog number is T131058.
价 格：￥电议型 号：T131058产 地：中国大陆
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T13105TD-428；化合物 T13105TD-428
TD-428 is a highly specific degrader of BRD4(DC50 of 0.32 nM). TD-428 is a BET PROTAC, which comprises TD-106 (a CRBN ligand) linked to JQ1 (a BET inhibitor). TD-428 efficiently induce BET protein degradation.
价 格：￥电议型 号：T13105产 地：中国大陆
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T12766RPR121056；化合物 T12766APC；APC
RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.
价 格：￥电议型 号：T12766产 地：中国大陆
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T125105N-Malonyltryptophan；化合物 N-MalonyltryptophanN-Malonyltryptophan
N-Malonyltryptophan is a useful organic compound for research related to life sciences. The catalog number is T125105 and the CAS number is 29399-11-9.
价 格：￥电议型 号：T125105产 地：中国大陆
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T124105Carbamic acid；化合物 Carbamic acidCarbamic acid
Carbamic acid is a useful organic compound for research related to life sciences and the catalog number is T124105.
价 格：￥电议型 号：T124105产 地：中国大陆
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T12105MRK-016；化合物 T12105MRK-016
MRK-016 is a selective, orally bioavailable inverse GABAA α5 receptor agonist.
价 格：￥电议型 号：T12105产 地：中国大陆
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T11606ICA-105665；化合物 T11606PF-04895162；PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格：￥电议型 号：T11606产 地：中国大陆
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T11584Hydroxy desmethyl Bosentan；化合物 T11584Ro 64-1056；Ro 64-1056
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver.
价 格：￥电议型 号：T11584产 地：中国大陆
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T11477GSK1059865；化合物 T11477GSK1059865
GSK1059865 is a potent antagonist of the orexin 1 receptor.
价 格：￥电议型 号：T11477产 地：中国大陆
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T11293(±)-Fabesetron hydrochloride；化合物 T11293FK1052 hydrochloride；FK1052 hydrochloride
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
价 格：￥电议型 号：T11293产 地：中国大陆
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T11123DuP 105；化合物DuP 105DuP 105
DuP 105 is an oral oxazolidinone, a novel synthetic antimicrobial compound effective against gram-positive bacteria.
价 格：￥电议型 号：T11123产 地：中国大陆
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T11107DSP-1053；化合物 T11107DSP-1053
Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.
价 格：￥电议型 号：T11107产 地：中国大陆
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T11105DS88790512；化合物 T11105DS88790512
DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.
价 格：￥电议型 号：T11105产 地：中国大陆
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T11059DM4-SMe；化合物 T11059DM4-SMe
DM4-SMe is a cytotoxic part of antibody-drug conjugates (ADCs) and a metabolite of antibody-maytansin conjugates (AMCs) and tubulin inhibitors, which can also be stabilized by disulfide bonds or thioether The bond binds to the antibody. The IC50 of DM4-SMe on KB cells was 0.026 nM.
价 格：￥电议型 号：T11059产 地：中国大陆
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T11058DM3；化合物 T11058Maytansinoid DM3；Maytansinoid DM3
DM3 (Maytansinoid DM3) is a maytansine mimic containing disulfide or thiol groups and a tubulin inhibitor. It is the cytotoxic part of antibody-drug conjugates (ADCs) .
价 格：￥电议型 号：T11058产 地：中国大陆
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T11057DM3-SMe；化合物 T11057DM3-SMe
DM3-SMe is a maytansine derivative and tubulin inhibitor. It is a cytotoxic part of antibody-drug conjugates (ADCs) and can bind to antibodies via disulfide bonds or stable thioether bonds. DM3-SMe has high cytotoxic activity in vitro with IC50 of 0.0011 nM.
价 格：￥电议型 号：T11057产 地：中国大陆
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T11056DLK-IN-1；化合物 T11056DLK-IN-1
DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer´s disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration exceeds the concentration required for DLK inhibition in the brain, so it has good tolerance Acceptability.
价 格：￥电议型 号：T11056产 地：中国大陆
