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  • T61222Antituberculosis agent-1；化合物 Antituberculosis agent-1Antituberculosis agent-1

    Antituberculosis Agent-1 (Compound 8a) is an effective antituberculosis agent, demonstrating a minimum inhibitory concentration (MIC) of 3.84 μg/mL against Mycobacterium tuberculosis H37Rv [1].

    价 格：￥电议型 号：T61222产 地：中国大陆

  • T61206AChE/BChE/BACE-1-IN-1；化合物 AChE/BChE/BACE-1-IN-1AChE/BChE/BACE-1-IN-1

    AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 values of 0.058 μM, 0.082 μM, and 0.115 μM against hAChE, hBChE, and hBACE-1, respectively. AChE/BChE/BACE-1-IN-1 exhibits significant binding affinity with PAS-AChE, excellent ability to cross the blood-brain barrier, potential disassembly of amyloid-beta (Aβ) aggregates, and ne

    价 格：￥电议型 号：T61206产 地：中国大陆

  • T61149Antibacterial agent 121；化合物 Antibacterial agent 121Antibacterial agent 121

    Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1].

    价 格：￥电议型 号：T61149产 地：中国大陆

  • T61126Antibacterial synergist 1；化合物 Antibacterial synergist 1Antibacterial synergist 1

    Antibacterial synergist 1 (compound 20P) is a potent inhibitor of bacterial biofilm formation. It effectively suppresses the production of pyocyanin, with an IC 50 of 8.6 μM, and inhibits biofilm formation with an IC 50 of 4.5 μM. Antibacterial synergist 1 shows promise in the research of P. aeruginosa infections [1].

    价 格：￥电议型 号：T61126产 地：中国大陆

  • T61123Antibacterial agent 111；化合物 Antibacterial agent 111Antibacterial agent 111

    Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongly binding to specific residues of tyrosyl-tRNA synthetase [1].

    价 格：￥电议型 号：T61123产 地：中国大陆

  • T61051ANO1-IN-1；化合物ANO1-IN-1ANO1-IN-1

    ANO1-IN-1, a selective ANO1 channel blocker, inhibited ANO1 and ANO2 with IC50 values of 2.56 μM and 15.43 μM, respectively.ANO1-IN-1 had a significant inhibitory effect on the proliferation of glioma cells.

    价 格：￥电议型 号：T61051产 地：中国大陆

  • T61049AChE-IN-11；化合物 AChE-IN-11AChE-IN-11

    AChE-IN-11 (compound 5C) can be used in the Alzheimer´s disease research with neuroprotective effects and good antioxidant activity (ORAC = 2.5 eq). AChE-IN-11 is a good multifunctional agent with IC 50 values of 7.9 μM, 9.9 μM, and 8.3 μM against AChE, MAO-B, and BACE1. AChE-IN-11 has a mixed-type AChE inhibition that can bind to the CAS and PAS of AChE. AChE-IN-11 is also a selective metal ions chelator [1].

    价 格：￥电议型 号：T61049产 地：中国大陆

  • T61023Antitubercular agent-21；化合物 Antitubercular agent-21Antitubercular agent-21

    Antitubercular agent-21 (Compound 15) is an antitubercular agent with low cytotoxicity. The MIC of Antitubercular agent-21 against M. tuberculosis H 37 R v. is 0.4 μg/mL. However, Antitubercular agent-21 shows lower activity against other microorganism, for example, bacteria gram-positive, gram-negative or fungi [1].

    价 格：￥电议型 号：T61023产 地：中国大陆

  • T61004AEP-IN-1；化合物 AEP-IN-1AEP-IN-1

    APE-IN-1 can be used for the early diagnosis and drug research of Alzheimer´s disease. APE-IN-1 is a potent Asparagine endopeptidase (AEP) inhibitor with IC 50 value of 89 nM [1].

    价 格：￥电议型 号：T61004产 地：中国大陆

  • T60965Anticandidal agent-1；化合物 Anticandidal agent-1Anticandidal agent-1

    Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent that inhibits biofilm through blocking hyphal elongation and filamentation. Anticandidal agent-1 exhibits anticandidal activity against C. glabrata and C. albicans, with MIC 50 values of 13.51 and 8.65 μg/mL, respectively [1].

    价 格：￥电议型 号：T60965产 地：中国大陆

  • T60915A1AR antagonist 5；化合物 A1AR antagonist 5A1AR antagonist 5

    A1AR antagonist 5 (compound 20) is a potent and selective antagonist of A1 adenosine receptor (A1AR) with a pKi of 6.11 and a pIC 50 of 5.83 [1].

    价 格：￥电议型 号：T60915产 地：中国大陆

  • T60891AChE/BChE/MAO-B-IN-1；化合物AChE/BChE/MAO-B-IN-1AChE/BChE/MAO-B-IN-1

    AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.

    价 格：￥电议型 号：T60891产 地：中国大陆

  • T60867Dyrk1A-IN-4；化合物 Dyrk1A-IN-4Dyrk1A-IN-4

    Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 dual inhibitor with anticancer effects. The IC50 values of Dyrk1A-IN-4 for DYRK1A and DYRK2 are 2 nM and 6 nM, respectively [1].

    价 格：￥电议型 号：T60867产 地：中国大陆

  • T60851Apoptotic agent-1；化合物 Apoptotic agent-1Apoptotic agent-1

    Apoptotic agent-1 (Compound 8a) induces Fas receptor and Cyto C genes over-expression that is an apoptotic agent with high antiproliferative activity against cancer cells as well as low cytotoxic effect [1].

    价 格：￥电议型 号：T60851产 地：中国大陆

  • T60824Dyrk1A-IN-3；化合物 Dyrk1A-IN-3Dyrk1A-IN-3

    Dyrk1A-IN-3 (Compound 8b) is a highly selective inhibitor of dual-specificity tyrosine-regulated kinase 1A (DYRK1A). Dyrk1A-IN-3 has high binding affinity of DYRK1A with an IC 50 of 76 nM. Dyrk1A-IN-3 can be used in neurodegenerative disorders research, for example, Alzheimer’s Disease, Huntington’s Disease, and Parkinson’s Disease [1].

    价 格：￥电议型 号：T60824产 地：中国大陆

  • T60801AY1511；化合物 AY1511AY1511

    AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].

    价 格：￥电议型 号：T60801产 地：中国大陆

  • T6080NVP-AEW541；化合物NVP-AEW541AEW541；AEW541

    NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based assay.

    价 格：￥电议型 号：T6080产 地：中国大陆

  • T60791Antitubercular agent-11；化合物 Antitubercular agent-11Antitubercular agent-11

    Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].

    价 格：￥电议型 号：T60791产 地：中国大陆

  • T60783Aurora/LIM kinase-IN-1；化合物 Aurora/LIM?kinase-IN-1Aurora/LIM kinase-IN-1

    Aurora/LIM kinase-IN-1 (Compound F114) is a potent aurora and lim kinase dual inhibitor. Aurora/LIM kinase-IN-1 inhibits the proliferation and invasion of GBM that may be used in drug development efforts for GBM, furthermore other cancers. Aurora kinases and lim kinases are the kinases which involved in neoplastic cell division and cell motility, respectively [1].

    价 格：￥电议型 号：T60783产 地：中国大陆

  • T60732A2A/A1 AR antagonist-1；化合物 A2A/A1?AR antagonist-1A2A/A1 AR antagonist-1

    A2A/A1 AR antagonist-1 (compound 1a) has the potential for ischemic stroke research which is potent A 2A /A 1 AR dual antagonist with Ki s of 5.58 and 24.2 nM, respectively [1].

    价 格：￥电议型 号：T60732产 地：中国大陆

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