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T27061CP-24879 hydrochlorideCP 24879 hydrochloride;CP24879 hydrochloride;CP-24879 HCl
CP-24879 hydrochloride, a Δ5D/Δ6D dual-inhibitor, can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 hydrochloride exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treat
价 格:¥电议型 号:T27061产 地:中国大陆
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T27026CJ-13,610CJ-13610;CJ 13610
CJ-13610 is an orally active 5-lipoxygenase (5-LO) inhibitor. CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
价 格:¥电议型 号:T27026产 地:中国大陆
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T26869BMS-986122BMS986122;BMS 986122
BMS 986122 is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing μ-opioid receptors (EC50 = 3 μM).
价 格:¥电议型 号:T26869产 地:中国大陆
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T2684JNJ-1661010JNJ 1661010;Takeda-25;JNJ1661010
JNJ-1661010 is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.
价 格:¥电议型 号:T2684产 地:中国大陆
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T26619AmitivirLY217896;LY-217896;LY 217896;阿米替韦
Amitivir is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffective in modifying the virologic or clinical co
价 格:¥电议型 号:T26619产 地:中国大陆
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T26613LAmbazone安巴腙;Primal;Ambazon
Ambazone was found to be active against various transplantable tumors in mice as well as rats.
价 格:¥电议型 号:T26613L产 地:中国大陆
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T2661TGX-221TGX221;TGX 221
TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.
价 格:¥电议型 号:T2661产 地:中国大陆
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T2654GSK2656157
GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay. The selectivty is 500-fold higher against a panel of 300 kinases.
价 格:¥电议型 号:T2654产 地:中国大陆
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T26193SKLB-163SKLB163;SKLB 163
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
价 格:¥电议型 号:T26193产 地:中国大陆
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T2619CH5132799
CH5132799 has been used in trials studying the treatment of Solid Tumors.
价 格:¥电议型 号:T2619产 地:中国大陆
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T2618LGK974LGK 974;WNT974;LGK-974;NVP-LGK974
LGK-974 is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
价 格:¥电议型 号:T2618产 地:中国大陆
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T2617SNS-314 MesylateSNS-314
SNS-314 Mesylate is an effective and specific Aurora A/B/C inhibitor (IC50: 9/31/3 nM). It is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.
价 格:¥电议型 号:T2617产 地:中国大陆
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T2616PIK-93PIK 93;PIK93
PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.
价 格:¥电议型 号:T2616产 地:中国大陆
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T2615Flavopiridol hydrochlorideHL 275;Alvocidib Hydrochloride;FLAVOPIRIDOL HCL;NSC 649890 HCl;MDL 107826A
Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulati
价 格:¥电议型 号:T2615产 地:中国大陆
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T2611CCT 137690CCT137690
CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).
价 格:¥电议型 号:T2611产 地:中国大陆
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T2561MacitentanACT-064992;马西替坦
Macitentan is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).
价 格:¥电议型 号:T2561产 地:中国大陆
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T2461PIK-90PIK 90;PIK90
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .
价 格:¥电议型 号:T2461产 地:中国大陆
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T2440IC261SU-5607
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
价 格:¥电议型 号:T2440产 地:中国大陆
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T23861CAY10526CAY-10526;CAY 10526;BTH
CAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
价 格:¥电议型 号:T23861产 地:中国大陆