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T77000Cirevetmab;化合物 CirevetmabCirevetmab
Cirevetmab (ZTS-00521426), a caninized monoclonal antibody targeting Canis lupus familiaris TGFB1, is classified as an immunoglobulin G2-kappa. It functions as an immunomodulator [1].
价 格:¥电议型 号:T77000产 地:中国大陆
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T76999Cilgavimab;化合物 CilgavimabCilgavimab
Cilgavimab (AZD-1061; COV2-2130), a humanized SARS-CoV-2-neutralizing monoclonal antibody, forms part of the monoclonal antibody combination AZD7442 with Tixagevimab. It demonstrates protective effects in mouse models of SARS-CoV-2 infection [1].
价 格:¥电议型 号:T76999产 地:中国大陆
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T76998Cevostamab;化合物 CevostamabCevostamab
Cevostamab (BFCR4350A; RG6160; RO7187797), a humanized IgG1-based bi-specific antibody (BsAb), specifically targets the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells and CD3 on T cells. It enhances synapse formation and augments T cell-mediated killing of MM tumor cells [1] [2].
价 格:¥电议型 号:T76998产 地:中国大陆
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T76997Socazolimab;化合物 SocazolimabSocazolimab
Socazolimab (ZKAB001), an anti-PD-L1 monoclonal antibody, demonstrates enduring safety and efficacy in treating recurrent or metastatic cervical cancer. Additionally, it shows promise for treating small cell lung cancer, esophageal squamous cell carcinoma (ESCC), advanced urothelial carcinoma, and osteosarcoma [1] [2] [3] [4] [5].
价 格:¥电议型 号:T76997产 地:中国大陆
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T76996Solitomab;化合物 SolitomabSolitomab
Solitomab (AMG 110), a bispecific antibody targeting CD3 and EpCAM, is utilized in researching primary uterine and ovarian carcinosarcoma cancer [1] [2].
价 格:¥电议型 号:T76996产 地:中国大陆
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T76994Sotevtamab;化合物 SotevtamabSotevtamab
Sotevtamab (16B5), a humanized IgG2 monoclonal antibody (mAb) targeting clusterin, acts as an inhibitor of the epithelial to mesenchymal transition, making it a valuable agent for cancer research [1] [2] [3].
价 格:¥电议型 号:T76994产 地:中国大陆
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T76992Suptavumab;舒他伏单抗REGN2222;REGN2222
Suptavumab (REGN2222) is a human monoclonal antibody. Suptavumab neutralizes conserved epitopes on subtypes A and B on RSV. Suptavumab can be used to study RSV infections and the respiratory system.
价 格:¥电议型 号:T76992产 地:中国大陆
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T76991Suvizumab;化合物 SuvizumabSuvizumab
Suvizumab (KD-247), a neutralizing antibody against HIV-1, effectively neutralizes strains HIV-1 MN, HIV-1 SF2, and HIV-1 89.6, exhibiting IC50 values of 0.1 ?g/mL, 1.0 ?g/mL, and 0.2 ?g/mL, respectively. It demonstrates a significant reduction in viral load, indicating its efficacy in preventing HIV infection. Suvizumab is also well-tolerated, further supporting its potential as a preventative treatment for HIV [1] [2].
价 格:¥电议型 号:T76991产 地:中国大陆
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T76990Suvratoxumab;化合物 SuvratoxumabSuvratoxumab
Suvratoxumab (MEDI4893) is a high-affinity, long-acting humanized IgG1κ anti-α-toxin monoclonal antibody. It effectively neutralizes α-toxin, a principal virulence factor of S. aureus, enhancing survival and diminishing lung injury in an immunocompromised mouse model of pneumonia. Additionally, Suvratoxumab augments the antibacterial efficacy of Vancomycin and Linezolid [1] [2] [3].
价 格:¥电议型 号:T76990产 地:中国大陆
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T76989Tabituximab barzuxetan;化合物 Tabituximab barzuxetanTabituximab barzuxetan
Tabituximab barzuxetan (OTSA101-DTPA-90Y) is a radioimmunoconjugate composed of a humanized monoclonal antibody targeting FZD-10 (OTSA-101) , and labeled with Yttrium 90. Tabituximab barzuxetan shows antineoplastic activity. Tabituximab barzuxetan can be used for synovial sarcoma research [1] .
价 格:¥电议型 号:T76989产 地:中国大陆
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T76987Tarcocimab;化合物 TarcocimabTarcocimab
Tarcocimab (OG1953), a humanized IgG1-type anti-VEGFA monoclonal antibody, is utilized in research targeting conditions such as retinal vein occlusion (RVO) and wet age-related macular degeneration (AMD).
价 格:¥电议型 号:T76987产 地:中国大陆
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T76986Tarlatamab;化合物 TarlatamabTarlatamab
Tarlatamab (AMG-757) is a first-in-class, high-affinity, bispecific T-cell engager (BiTE) antibody that selectively targets delta-like ligand 3 (DLL3), a protein predominantly expressed in small-cell lung cancer (SCLC) tumors with minimal expression in normal tissues. It demonstrates dissociation constants (KDs) of 0.64 nM and 0.50 nM for DLL3 in human and nonhuman primates (NHP), respectively, and 14.9 nM and 12 nM for CD3 in human and NHP, accordingly. As a pioneering HLE BiTE immuno-oncology
价 格:¥电议型 号:T76986产 地:中国大陆
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T76985Tebotelimab;化合物 TebotelimabTebotelimab
Tebotelimab (MGD-013) is a bispecific antibody targeting PD-1 and LAG-3, classified as a human IgG4κ dual-affinity re-targeting (DART) molecule. It exhibits binding affinities with EC50 values of 1.65 nM for PD-1 and 0.41 nM for LAG-3 on NS0 cells. The compound effectively inhibits PD-1/PD-L1, PD-1/PD-L2, and LAG-3/HLA (MHC-II) interactions, alongside PD-1 signaling pathways. By doing so, Tebotelimab reinvigorates exhausted T-cell responses and bolsters antitumor immunity [1] [2] [3].
价 格:¥电议型 号:T76985产 地:中国大陆
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T76984Tecaginlimab;化合物 TecaginlimabTecaginlimab
Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, is designed for the dual targeting and conditional activation of CD40 and 4-1BB, aiming to improve the priming and reactivation of tumor-specific immunity [1].
价 格:¥电议型 号:T76984产 地:中国大陆
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T76982Teropavimab;化合物 TeropavimabTeropavimab
Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].
价 格:¥电议型 号:T76982产 地:中国大陆
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T76981Tibulizumab;化合物 TibulizumabTibulizumab
Tibulizumab (LY 3090106), a tetravalent bispecific monoclonal antibody, selectively binds to B-cell activating factor (BAFF) and IL-17A with dissociation constants (Kd) of 60 pM and 14 pM, respectively. This specificity renders it a valuable tool for autoimmune disease research.
价 格:¥电议型 号:T76981产 地:中国大陆
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T76980Tidutamab;化合物 TidutamabTidutamab
Tidutamab (XmAb-18087) is a bispecific antibody (bsAb) that is both humanized and optimized for affinity, targeting the SSTR2 and CD3 domains to bind to the somatostatin receptor 2 (SSTR2) and T cells, respectively. It features a full Fc domain to ensure an extended serum half-life. This compound engages in the targeted elimination of SSTR2-positive tumor cells via the mechanism of redirected T cell-mediated cytotoxicity (RTcC) [1].
价 格:¥电议型 号:T76980产 地:中国大陆
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T76979Tadocizumab;化合物 TadocizumabTadocizumab
Tadocizumab (C4G1; YM-337), a humanized monoclonal antibody targeting integrin αIIbβ3, exhibits antiplatelet and antithrombotic properties. It is utilized in research into cardiovascular diseases [1] [2].
价 格:¥电议型 号:T76979产 地:中国大陆
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T76978Siltuximab;司妥昔单抗CNTO-328;CNTO-328
Siltuximab(CNTO-328) is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.
价 格:¥电议型 号:T76978产 地:中国大陆
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T76977Timigutuzumab;化合物 TimigutuzumabTimigutuzumab
Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].
价 格:¥电议型 号:T76977产 地:中国大陆