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T0097MRT67307;化合物MRT67307MRT67307 HCl;MRT67307 HCl
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophages. MRT67307 is a kinase inhibitor that has been shown to inhibit TBK1, MARK1-4, IKKε, and NUAK1 (IC50 values are 19, 27-52, 160, and 230 nM, respectively), the salt-inducible kinases (SIKs; IC50s =250, 67, and 430 nM for SIK1, SIK2, and SIK3, respectively) and ULK1 and ULK2 (IC50
价 格:¥电议型 号:T0097产 地:中国大陆
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T0095Bendamustine hydrochloride;盐酸苯达莫司汀SDX-105|||SDX-105 (Cytostasane) HCl|||Bendamustine HCl|||EP-3101;S
Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.
价 格:¥电议型 号:T0095产 地:中国大陆
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T0093LSorafenib索拉非尼索拉非尼|||Bay 43-9006
Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity and can induce autophagy and apoptosis as well as agonistic iron death.
价 格:¥电议型 号:T0093L产 地:中国大陆
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T0093Sorafenib tosylate甲苯磺酸索拉非尼甲苯磺酸索拉非尼|||Bay 43-9006
Sorafenib tosylate (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity and can induce autophagy and apoptosis as well as agonistic iron death.
价 格:¥电议型 号:T0093产 地:中国大陆
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T0085LEntecavir;恩替卡韦BMS200475|||SQ34676;BMS200475|||SQ34676|||恩替卡韦
Entecavir (SQ34676) is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares of the underlying hepatitis B during or after therapy, but has not been linked to cases of clinically apparent liver injury.
价 格:¥电议型 号:T0085L产 地:中国大陆
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T0085Entecavir monohydrate;恩替卡韦 (1水合物)SQ 34676|||BMS-200475|||Entecavir hydrate;SQ 34676|||BMS-200475|||E
Entecavir monohydrate (BMS-200475) is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.
价 格:¥电议型 号:T0085产 地:中国大陆
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T0084Moclobemide;吗氯贝胺Ro111163;吗氯贝胺|||Ro111163
Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.
价 格:¥电议型 号:T0084产 地:中国大陆
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T0083Eplerenone;依普利酮Epoxymexrenone|||CGP 30083|||SC-66110;Epoxymexrenone|||CGP 30083|||依普利酮|||SC-66110
Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase levels, but has yet to be linked to cases of clinically apparent drug induced liver disease.
价 格:¥电议型 号:T0083产 地:中国大陆
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T0082Domperidone;多潘立酮R33812;R33812|||多潘立酮
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).
价 格:¥电议型 号:T0082产 地:中国大陆
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T0081Lafutidine拉呋替丁拉呋替丁|||FRG-8813
Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.
价 格:¥电议型 号:T0081产 地:中国大陆
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T0074LChlorprothixene hydrochloride;泰尔登盐酸盐NSC 78193|||Minithixen|||Truxal hydrochloride|||NSC 56379|||NSC
Chlorprothixene hydrochloride (Truxal hydrochloride) brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene hydrochloride s a typical antipsychotic drug of the thioxanthene (tricyclic) class.
价 格:¥电议型 号:T0074L产 地:中国大陆
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T0073Octinoxate;甲氧基肉桂酸辛酯2-Ethylhexyl 4-methoxycinnamate|||ethylhexyl methoxycinnamate|||Octyl 4-methoxyci
Octinoxate (Octyl 4-methoxycinnamate) is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage,primarily as an ingredient in some sunscreens and lip balms. It is also used to reduce the appearance of scars.
价 格:¥电议型 号:T0073产 地:中国大陆
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T0063L-Isoleucine;L-异亮氨酸isoleucine|||Ile;异亮氨酸|||isoleucine|||Ile|||L-异亮氨酸
L-Isoleucine (Ile) is an essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.
价 格:¥电议型 号:T0063产 地:中国大陆
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T0053Hydroxyzine Pamoate;双羟萘酸羟嗪Hydroxyzine embonate|||Bobsule|||Equipose;Hydroxyzine embonate|||双羟萘酸羟嗪|||
Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
价 格:¥电议型 号:T0053产 地:中国大陆
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T0045Heptaminol hydrochloride盐酸庚胺醇盐酸庚胺醇|||RP-2831 hydrochloride
Heptaminol hydrochloride (RP-2831 hydrochloride), a vasoconstrictor, is used in the therapy of hypotension, especially orthostatic hypotension.
价 格:¥电议型 号:T0045产 地:中国大陆
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T0040Quinestrol炔雌醇环戊醚W-3566|||Ethinylestradiol 3-cyclopentyl ether|||炔雌醇环戊醚|||EE2CPE
Quinestrol (Ethinylestradiol 3-cyclopentyl ether) is a synthetic estrogen, applied in hormone replacement therapy, and occasionally to use in cancer and prostate cancer treatment.
价 格:¥电议型 号:T0040产 地:中国大陆
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T0039Dapoxetine;达波西汀Dapoxetina|||Dapoxetinum;达波西汀|||Dapoxetina|||Dapoxetinum
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
价 格:¥电议型 号:T0039产 地:中国大陆
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T0038Doxapram hydrochloride hydrate;多沙普仑盐酸一水合物Doxapram hydrochloride monohydrate|||Doxapram HCl;多沙普仑盐酸一水合
Doxapram hydrochloride hydrate (Doxapram HCl) effectively inhibits the function of TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channels, displaying EC50 values of 410 nM, 37 μM, and 9 μM, respectively.
价 格:¥电议型 号:T0038产 地:中国大陆
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T0037Halazone哈拉宗哈拉宗|||Cloritines|||Pantocid|||Halazon
Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
价 格:¥电议型 号:T0037产 地:中国大陆
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T003618β-Glycyrrhetinic acid18β-甘草次酸Enoxolone|||甘草次酸|||18β-甘草次酸|||Glycyrrhetin
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
价 格:¥电议型 号:T0036产 地:中国大陆