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T11345LLerociclib dihydrochloride;化合物Lerociclib dihydrochlorideG1T38 dihydrochloride;G1T38 dihydrochloride
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
价 格:¥电议型 号:T11345L产 地:中国大陆
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T11342G-5555 hydrochloride (1648863-90-4 free base);化合物 T11342G-5555 hydrochloride;G-5555 hydrochloride
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.
价 格:¥电议型 号:T11342产 地:中国大陆
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T11318Dopexamine hydrochloride;盐酸多培沙明FPL60278AR;盐酸多培沙明|||FPL60278AR
Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow.
价 格:¥电议型 号:T11318产 地:中国大陆
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T11313Forodesine hydrochloride化合物 T11313BCX-1777 hydrochloride|||Immucillin-H hydrochloride
Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.
价 格:¥电议型 号:T11313产 地:中国大陆
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T11311Foliglurax monohydrochloride;化合物 T11311PXT002331 (monohydrochloride);PXT002331 (monohydrochloride)
Foliglurax monohydrochloride Antiparkinsonian effect. is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM.
价 格:¥电议型 号:T11311产 地:中国大陆
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T11293(±)-Fabesetron hydrochloride;化合物 T11293FK1052 hydrochloride;FK1052 hydrochloride
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
价 格:¥电议型 号:T11293产 地:中国大陆
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T11281LFGI-106 tetrahydrochloride;化合物FGI-106 tetrahydrochlorideFGI-106 tetrahydrochloride
FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective concentrations (EC50s) of 100 nM, 800 nM, and 400-900 nM, respectively. Additionally, it effectively inhibits non-hemorrhagic fever viruses, notably HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively, indicating its broad-spectrum antiviral potential.
价 格:¥电议型 号:T11281L产 地:中国大陆
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T11239Ethacizine hydrochloride;乙沙西嗪盐酸盐NIK-244|||Ethacizin|||NIK-244 hydrochloride;NIK-244|||Ethacizin|||NI
Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction.
价 格:¥电议型 号:T11239产 地:中国大陆
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T11238LEtamicastat hydrochloride;依他米司特盐酸盐BIA 5-453 hydrochloride;BIA 5-453 hydrochloride
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.
价 格:¥电议型 号:T11238L产 地:中国大陆
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T11227LEravacycline dihydrochloride;伊拉瓦环素盐酸盐TP-434-046|||TP-434 dihydrochloride;TP-434-046|||TP-434 dihydro
Eravacycline dihydrochloride (TP-434-046)?is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).
价 格:¥电议型 号:T11227L产 地:中国大陆
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T11220LUK 227786;化合物T11220Lhydrochloride(150452-18-9 Free base)|||1-[4-(1,3-Benzodioxol-5a-ylmethylamino)-6
UK 227786 is an inhibitor of phosphodiesterase 5 (PDE5), used for treatment of prostatic diseases.
价 格:¥电议型 号:T11220L产 地:中国大陆
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T11213Epertinib hydrochloride;化合物Epertinib hydrochlorideS-22611 hydrochloride;S-22611 hydrochloride
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
价 格:¥电议型 号:T11213产 地:中国大陆
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T1120LDacarbazine hydrochloride;化合物 T1120LDacarbazine HCl;Dacarbazine HCl
Dacarbazine ( imidazole carboxamide) is a chemotherapy drug used to treat melanoma and Hodgkin´s lymphoma.
价 格:¥电议型 号:T1120L产 地:中国大陆
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T11197Enclomiphene D4 hydrochloride;化合物 T11197(E)-Clomiphene D4 hydrochloride|||Enclomifene D4 hydrochlori
Enclomiphene D4 hydrochloride ((E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property.Enclomiphene D4 hydrochloride ((E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a deuterium labeled Enclomiphene.
价 格:¥电议型 号:T11197产 地:中国大陆
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T11188LEmixustat hydrochloride;化合物Emixustat hydrochlorideACU-4429 hydrochloride;ACU-4429 hydrochloride
Emixustat hydrochloride (ACU-4429 hydrochloride) strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator.
价 格:¥电议型 号:T11188L产 地:中国大陆
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T11173LElacestrant S enantiomer dihydrochloride;化合物 T11173LRAD1901 S enantiomer dihydrochloride|||RAD-1901
Elacestrant (RAD1901) dihydrochloride is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant S enantiomer dihydrochloride is an low activity enantiomer of elacestrant dihydrochloride.
价 格:¥电议型 号:T11173L产 地:中国大陆
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T11172EIPA hydrochloride;化合物 T11172L593754 hydrochloride|||MH 12-43 hydrochloride;L593754 hydrochloride|||
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.
价 格:¥电议型 号:T11172产 地:中国大陆
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T1117Clorgyline hydrochloride;盐酸氯吉林Clorgiline hydrochloride;盐酸氯吉林|||Clorgiline hydrochloride|||N-[3-(2,4-
Clorgyline hydrochloride (Clorgiline hydrochloride), a white powder, is served as monoamine oxidase inhibitor.
价 格:¥电议型 号:T1117产 地:中国大陆
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T11168EHNA hydrochloride;外消旋-9-(2-羟基-3-壬基)腺嘌呤盐酸盐EHNA hydrochloride
EHNA hydrochloride is a chemical compound recognized for its antiviral, antitumor, and antiarrhythmic properties. It functions as a potent and selective inhibitor of both cyclic nucleotide phosphodiesterase 2 (PDE2) with an IC50 of 4 μM and adenosine deaminase (ADA). Additionally, it effectively inhibits the activity of cGMP-stimulated PDE II (cGs-PDE) with IC50 values of 0.8 μM in humans and 2 μM in porcine myocardium, although its inhibitory effects on unstimulated PDE2 activity are less prono
价 格:¥电议型 号:T11168产 地:中国大陆
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T11157LEGFR-IN-1 hydrochloride;EGFR-IN-1盐酸盐EGFR-IN-1 hydrochloride
EGFR-IN-1 hydrochloride is an irreversible and specific inhibitor of L858R/T790M mutant EGFR with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride exhibits potent antitumor and antiproliferative activity in H1975 cells and the mutant HCC827 cells with IC50s of 4 and 28 nM, respectively.
价 格:¥电议型 号:T11157L产 地:中国大陆