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T27307Fasnall
Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly in combination with carboplatin.
价 格:¥电议型 号:T27307产 地:中国大陆
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T2730Gossypol (acetic acid)醋酸棉酚;乙酸棉子酚;Pogosin;(±)-Gossypol-acetic acid;AT101;Gossypol acetic acid
Gossypol-acetic acid, a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.
价 格:¥电议型 号:T2730产 地:中国大陆
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T2699BMS 777607BMS777607;BMS-777607;BMS 817378
BMS-777607 is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
价 格:¥电议型 号:T2699产 地:中国大陆
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T26795PXS-4728ABI1467335;PXS 4728A;BI 1467335;BI-1467335;PXS4728A;BI-1467335 HCl
BI-1467335 is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].
价 格:¥电议型 号:T26795产 地:中国大陆
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T26745BAY 73-1449BAY73-1449;BAY-73-1449
BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
价 格:¥电议型 号:T26745产 地:中国大陆
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T2673A 438079 hydrochlorideA-438079 hydrochloride;A-438079 HCl;A 438079 (hydrochloride)
A-438079 hydrochloride is a potent and selective P2X7 receptor antagonist with pIC50 of 6.9.
价 格:¥电议型 号:T2673产 地:中国大陆
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T2586Cabozantinib卡博替尼;XL184;BMS-907351
Cabozantinib (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).
价 格:¥电议型 号:T2586产 地:中国大陆
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T2555Aclidinium bromide阿地溴铵;LAS-W 330;LAS 34273
Aclidinium is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis or emphysema. Aclidinium has not been implicated in causing liver enzyme elevations or clinically apparent acute live
价 格:¥电议型 号:T2555产 地:中国大陆
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T2500Cediranib西地尼布;AZD2171;NSC-732208
Cediranib (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit, selective more for VEGFR than PDGFR-α (36-f
价 格:¥电议型 号:T2500产 地:中国大陆
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T24897TP0427736TP427736;TP-0427736;TP-427736
TP0427736 is a potent and selective inhibitor of ALK5 with an IC50 of 2.72 nM, 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-β-induced growth inhibition in human outer root sheath cells and elongates the anagen phase in mouse h
价 格:¥电议型 号:T24897产 地:中国大陆
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T24730Roslin 2 bromideRoslin2;Roslin-2
Roslin 2 bromide is a p53 reactivator that disrupts the binding of FAK and p5Roslin 2 bromide exhibits anticancer effects.
价 格:¥电议型 号:T24730产 地:中国大陆
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T2473PLX-4720PLX4720
PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent to c-Raf-1(Y340D and Y341D mutations).
价 格:¥电议型 号:T2473产 地:中国大陆
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T2458CID755673
CID755673 is an effective and specific cell-active inhibitor for PKD (IC50: 182 nM); exhibits selective PKD1 inhibition when compared with PLK1, AKT, CAMKIIα, CAK, and PKC isoforms.
价 格:¥电议型 号:T2458产 地:中国大陆
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T2409Tenofovir alafenamideGS-7340;替诺福韦艾拉酚胺;替诺福韦
Tenofovir Alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.
价 格:¥电议型 号:T2409产 地:中国大陆
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T2406Cinacalcet hydrochloride盐酸西那卡塞;Cinacalcet HCl;Cinacalcet;AMG-073 hydrochloride;AMG-073 HCl
Cinacalcet hydrochloride is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-sensing receptors to serum calcium. This action reduces parathyroid hormone secretion and decreases serum calcium in th
价 格:¥电议型 号:T2406产 地:中国大陆
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T23733Amperozide安哌齐持;Amperozidum;Amperozida;FG 5606
Amperozide, a 5-HT2 antagonist, attenuates craving for cocaine by rats and reduces agonistic behaviors such as slashing and biting in pigs.
价 格:¥电议型 号:T23733产 地:中国大陆
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T2373VipadenantBIIB-014;CEB-4520
Vipadenant(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM).
价 格:¥电议型 号:T2373产 地:中国大陆
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T2371EmapunilAC-5216;XBD-173
Emapunil is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
价 格:¥电议型 号:T2371产 地:中国大陆
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T23154PiclamilastRPR 73401;RP 73401;吡拉米司特
Piclamilast is a PDE4 inhibitor.
价 格:¥电议型 号:T23154产 地:中国大陆