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T14671BMS-193885;化合物BMS-193885BMS-193885
BMS-193885 is a selective, brain-penetrant, and competitive antagonist of the neuropeptide Y1 receptor with a Ki of 3.3 nM, and an IC50 of 5.9 nM for hY1.
价 格:¥电议型 号:T14671产 地:中国大陆
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T14670BMS-1166 hydrochloride;化合物 T14670BMS-1166 hydrochloride
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
价 格:¥电议型 号:T14670产 地:中国大陆
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T14669BMS-066;化合物 T14669BMS-066
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
价 格:¥电议型 号:T14669产 地:中国大陆
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T1448LDasatinib monohydrate;达沙替尼BMS-354825 Monohydrate;达沙替尼|||BMS-354825 Monohydrate
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
价 格:¥电议型 号:T1448L产 地:中国大陆
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T1448Dasatinib达沙替尼BMS-354825|||达沙替尼
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and lymphoma.
价 格:¥电议型 号:T1448产 地:中国大陆
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T1293Gatifloxacin;加替沙星BMS 206584-01|||PD 135432|||CG5501|||BMS-206584|||AM-1155;BMS 206584-01|||PD 135432
Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
价 格:¥电议型 号:T1293产 地:中国大陆
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T12694Razaxaban hydrochloride;化合物 T12694BMS 561389 hydrochloride|||DPC 906 hydrochloride;BMS 561389 hydroc
Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.
价 格:¥电议型 号:T12694产 地:中国大陆
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T12663(Rac)-BMS-816336;化合物 T12663(Rac)-BMS-816336
(Rac)-BMS-816336 (Compound 6n), a racemate of BMS-816336, is a potent inhibitor of the human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme, demonstrating IC50 values of 10 nM and 68 nM, respectively. It exhibits good metabolic stability [1].
价 格:¥电议型 号:T12663产 地:中国大陆
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T12400Peliglitazar racemate;培利格列扎外消旋体(Rac)-Peliglitazar|||(Rac)-BMS 426707-01|||BMS 426707-01 racemate;(Ra
Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity agent.
价 格:¥电议型 号:T12400产 地:中国大陆
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T12143N-deacetylated BMS-202;化合物 T12143N-deacetylated BMS-202
N-deacetylated BMS-202 is the deacetylated of BMS-202.
价 格:¥电议型 号:T12143产 地:中国大陆
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T11740Delcasertib;化合物DelcasertibKAI-9803|||BMS-875944;KAI-9803|||BMS-875944
Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).
价 格:¥电议型 号:T11740产 地:中国大陆
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T11675Irbesartan-d4;厄贝沙坦 D4SR-47436 D4|||BMS-186295 D4;厄贝沙坦 D4|||SR-47436 D4|||BMS-186295 D4
Irbesartan D4, a deuterium-labeled variant of Irbesartan, is a highly potent and specific antagonist of the angiotensin II type 1 (AT1) receptor.
价 格:¥电议型 号:T11675产 地:中国大陆
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T11514Gusperimus trihydrochloride;化合物 T11514NKT-01|||BMS181173|||Spanidin;NKT-01|||BMS181173|||Spanidin
Gusperimus trihydrochloride is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity.
价 格:¥电议型 号:T11514产 地:中国大陆
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T11494GSK3532795;化合物 T11494BMS-955176;BMS-955176
GSK3532795 is a potent, orally active, second-generation HIV-1 maturation inhibitor (EC50s: 10.2, 1.9, 2.7, and 13 nM for HIV-1 WT(human serum), HIV-1 WT, HIV-1 V370A, and HIV-1 ΔV370).
价 格:¥电议型 号:T11494产 地:中国大陆
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T10958Dapagliflozin-d5;化合物 T10958BMS-512148 D5;BMS-512148 D5
Dapagliflozin D5 (BMS-512148 D5) is deuterated Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.
价 格:¥电议型 号:T10958产 地:中国大陆
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T10571BMS-901715;化合物 T10571BMS-901715
BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).
价 格:¥电议型 号:T10571产 地:中国大陆
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T10570Fostemsavir Tris;化合物Fostemsavir TrisBMS-663068 Tris;BMS-663068 Tris
Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and interfering with the attachment of virus to CD4+ T-cells.
价 格:¥电议型 号:T10570产 地:中国大陆
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T10569BMS-654457;化合物 T10569BMS-654457
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
价 格:¥电议型 号:T10569产 地:中国大陆
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T10568BMS-470539 dihydrochloride;化合物 T10568BMS-470539 dihydrochloride
BMS-470539 dihydrochloride is a highly potent and selective agonist of the melanocortin-1 receptor (MC-1R; IC50: 120 nM; EC50: 28 nM) with anti-inflammatory properties. It does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R.
价 格:¥电议型 号:T10568产 地:中国大陆
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T10567BMS-214662;化合物 T10567BMS-214662
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors, and has the ability to selectively target CML stem cells/progenitors with antitumor activity.
价 格:¥电议型 号:T10567产 地:中国大陆