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T4391Syk Inhibitor II (hydrochloride)
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibit
价 格:¥电议型 号:T4391产 地:中国大陆
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T4383GSK-J4 HydrochlorideGSK J4 HCl
GSK-J4 is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.
价 格:¥电议型 号:T4383产 地:中国大陆
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T4382Proguanil hydrochloride盐酸氯胍;Chlorguanide hydrochloride;Paludrine hydrochloride;Chloroquanil
Proguanil Hydrochloride is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction
价 格:¥电议型 号:T4382产 地:中国大陆
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T4370Resminostat hydrochlorideRAS2410 hydrochloride;4SC-201 hydrochloride
Resminostat hydrochloride is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent activities against HDAC8 (IC50: 877 nM).
价 格:¥电议型 号:T4370产 地:中国大陆
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T4369SCH-23390 hydrochlorideSCH 23390 hydrochloride;R-(+)-SCH23390 hydrochloride
SCH 23390 hydrochloride is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
价 格:¥电议型 号:T4369产 地:中国大陆
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T4361CBL0137 hydrochlorideCBLC137;CBL0137;Curaxin-137 hydrochloride;CBL-C137 hydrochloride;Curaxin 137
CBL0137 activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.
价 格:¥电议型 号:T4361产 地:中国大陆
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T4333Quinine dihydrochloride盐酸奎宁;Quinine bimuriate
Quinine Dihydrochloride is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).
价 格:¥电议型 号:T4333产 地:中国大陆
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T4327Prexasertib dihydrochloridePrexasertib HCl;LY2606368 (dihydrochloride);LY2606368
Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.
价 格:¥电议型 号:T4327产 地:中国大陆
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T4324PQ401 hydrochloride (196868-63-0(free base))
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
价 格:¥电议型 号:T4324产 地:中国大陆
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T4313Tinoridine hydrochloride盐酸替诺立定;Nonflamin;Y-3642 hydrochloride
Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 μM ascorbic acid in the renin gra
价 格:¥电议型 号:T4313产 地:中国大陆
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T4291(+)-Isocorydine hydrochloride盐酸异可利定;Isocorydine HCl
(+)-Isocorydine is a eukaryote protein kinases Inhibitor.
价 格:¥电议型 号:T4291产 地:中国大陆
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T4276Hydroxyfasudil Hydrochloride羟基法舒地尔盐酸盐;RHO-激酶抑制剂;Hydroxyfasudil (HA-1100) HCl;HA 1100 hydrochloride
Hydroxyfasudil hydrochloride is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).
价 格:¥电议型 号:T4276产 地:中国大陆
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T4274Melitracen hydrochlorideMelixeran;Thymeol hydrochloride;盐酸美利曲辛;盐酸美力他欣
Melitracen Hydrochloride, an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.
价 格:¥电议型 号:T4274产 地:中国大陆
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T4261BPR1J-097 hydrochloride (1327167-19-0(free base))
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
价 格:¥电议型 号:T4261产 地:中国大陆
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T4249AZD3759 hydrochloride
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
价 格:¥电议型 号:T4249产 地:中国大陆
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T4247I-CBP112 hydrochloride
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly reduced the leukemia-initiating poten
价 格:¥电议型 号:T4247产 地:中国大陆
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T4236AR-M 1000390 hydrochlorideARM-390 HCl;ARM390 Hydrochloride
AR-M 1000390 (hydrochloride), also known as ARM-390, is a low-internalizing nonpeptidic δ-selective opioid receptor agonist; derivative of SNC 80. Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain pe
价 格:¥电议型 号:T4236产 地:中国大陆
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T4234HJC0152 hydrochlorideHJC0152
HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor.
价 格:¥电议型 号:T4234产 地:中国大陆
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T4230PF-3758309 hydrochloridePF-03758309 hydrochloride
PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activit
价 格:¥电议型 号:T4230产 地:中国大陆
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T4229S1RA hydrochlorideE-52862 hydrochloride;4-[2-[[5-甲基-1-(2-萘基)-1H-吡唑-3-基]氧基]乙基]吗啉盐酸盐(1:1)
S1RA HCl (E-52862 HCl) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1000 nM).
价 格:¥电议型 号:T4229产 地:中国大陆