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T21675SB 203580 hydrochloride;化合物 T21675SB 203580 hydrochloride
Adezmapimod (SB 203580) hydrochloride is a selective ATP-competitive inhibitor of p38 MAPK, displaying IC50 values of 50 nM for SAPK2a/p38 and 500 nM for SAPK2b/p38β2. This compound also inhibits LCK, GSK3β, and PKBα, albeit with IC50 values 100-500 times higher than those for SAPK2a/p38. Additionally, Adezmapimod hydrochloride acts as an activator of autophagy and mitophagy [1].
价 格:¥电议型 号:T21675产 地:中国大陆
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T21637SB-505124 hydrochloride;化合物 T21637SB-505124 hydrochloride
SB-505124 hydrochloride functions as a selective, concentration-dependent inhibitor targeting TGF-β Receptor type I (ALK4, ALK5, ALK7), exhibiting IC50 values of 129 nM for ALK4 and 47 nM for ALK5. Notably, it does not affect ALK1, 2, 3, or 6.
价 格:¥电议型 号:T21637产 地:中国大陆
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T21627Hoechst 33342 trihydrochloride化合物Hoechst 33342 trihydrochlorideHOE 33342 trihydrochloride|||bisBenzi
Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.
价 格:¥电议型 号:T21627产 地:中国大陆
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T21505Suberoyl bis-hydroxamic acid;软木肟酸SBHA|||Suberohydroxamic acid;SBHA|||软木肟酸|||Suberohydroxamic acid
Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on the N-terminal of the core histones.
价 格:¥电议型 号:T21505产 地:中国大陆
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T21503(E/Z)-Zotiraciclib;化合物(E/Z)-Zotiraciclib(E/Z)-TG02|||(E/Z)-SB1317;(E/Z)-TG02|||(E/Z)-SB1317
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.
价 格:¥电议型 号:T21503产 地:中国大陆
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T2128SBI-0206965;化合物SBI-0206965SBI0206965;SBI0206965
SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.
价 格:¥电议型 号:T2128产 地:中国大陆
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T2103Ispinesib;伊斯平斯CK0238273|||SB-715992;伊匹尼塞|||伊斯平斯|||CK0238273|||SB-715992
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
价 格:¥电议型 号:T2103产 地:中国大陆
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T21000PiB;2-(4-(二甲基氨基)苯基)苯并[D]噻唑-6-醇Pittsburgh Compound-B|||6-OH-BTA-1;2-(4-(二甲基氨基)苯基)苯并[D]噻唑-6-醇|||Pittsb
PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer´s disease diagnosis.
价 格:¥电议型 号:T21000产 地:中国大陆
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T20754Deltamethrin溴氰菊酯Butoss|||RU-22974|||Esbecythrin|||溴氰菊酯|||K-Othrin|||Decamethrin|||RU 22974
Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.
价 格:¥电议型 号:T20754产 地:中国大陆
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T20662Gemifloxacin;化合物 T20662SB-265805|||SB 265805|||SB265805;SB-265805|||SB 265805|||SB265805
Gemifloxacin is a fluoronaphthyridone with strong antibacterial effect.
价 格:¥电议型 号:T20662产 地:中国大陆
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T20660Revaprazan;化合物 T20660SB-641257|||SB 641257|||SB641257;SB-641257|||SB 641257|||SB641257
Revaprazan is a novel, selective potassium-competitive acid blocker, to be specific, it reversibly inhibits gastric H(+)/K(+)-ATPase and shows effective acid suppression comparable to PPIs.
价 格:¥电议型 号:T20660产 地:中国大陆
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T20218S-Bioallethrin化合物 T20218Esbioallethrin|||AI-3-29024|||AI3-29024|||AI 3-29024
S-Bioallethrin is a pure S-form of Bioallethrin.
价 格:¥电议型 号:T20218产 地:中国大陆
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T2009SB-3CT;化合物SB-3CTSB-3CT
SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).
价 格:¥电议型 号:T2009产 地:中国大陆
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T19942SBA Crosslinker;化合物 T19942SBA Cross-linker|||SBA Cross linker;SBA Cross-linker|||SBA Cross linker
SBA crosslinker is a sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms. SBA Crosslinker is useful for making antibody-drug conjugates.
价 格:¥电议型 号:T19942产 地:中国大陆
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T19925EcDsbB-IN-9;4,5-二氯-2-苄基-3(2H)-哒嗪EcDsbB-IN-9
EcDsbB-IN-9 is a specific EcDsbB inhibitor, targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria.
价 格:¥电议型 号:T19925产 地:中国大陆
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T19690SB 224289;化合物 T19690SB224289|||SB-224289;SB224289|||SB-224289
SB 224289 is a selective antagonist of 5-HT1B receptor with pKi of 8.2. It is a centrally active following oral administration in vivo. SB 224289 displays 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays.
价 格:¥电议型 号:T19690产 地:中国大陆
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T19669SB399885;化合物T19669SB399885 Hydrochloride|||SB 399885|||SB399885|||SB-399885;SB399885 Hydrochloride||
SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).
价 格:¥电议型 号:T19669产 地:中国大陆
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T1955SB225002;化合物SB225002SB225002
SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
价 格:¥电议型 号:T1955产 地:中国大陆
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T19275Desbutyl Lumefantrine D9;化合物 T19275Desbutyl-benflumetol D9;Desbutyl-benflumetol D9
Desbutyl Lumefantrine D9, a deuterium-labeled metabolite of Lumefantrine, exhibits the incorporation of deuterium atoms.
价 格:¥电议型 号:T19275产 地:中国大陆
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T1890Pracinostat;化合物PracinostatSB939;SB939
Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral dosing. Data demonstrate that Pracinostat is a potent and effective anti-tumor drug with potential as an oral therapy for a variety of human hematological and solid tumors.
价 格:¥电议型 号:T1890产 地:中国大陆