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T11154LEG01377 2HCl；EG01377二盐酸盐EG01377 2HCl(2227996-00-9 Free base)；EG01377 2HCl(2227996-00-9 Free base)
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
价 格：￥电议型 号：T11154L产 地：中国大陆
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T11154EG01377；化合物 T11154EG01377
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.
价 格：￥电议型 号：T11154产 地：中国大陆
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T11153EG00229；化合物 T11153EG00229
EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2.
价 格：￥电议型 号：T11153产 地：中国大陆
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T11152Edaravone-d5；化合物 T11152MCI-186 D5；MCI-186 D5
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound´s attributes while offering isotopic labeling benefits.
价 格：￥电议型 号：T11152产 地：中国大陆
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T11151Ecteinascidin-Analog-1；化合物 T11151Ecteinascidin-Analog-1
Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities. Ecteinascidin-Analog-1 is a useful intermediate for chemical sythesis of Ecteinascidin analogues.
价 格：￥电议型 号：T11151产 地：中国大陆
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T11150Ecteinascidin 770；化合物 T11150Ecteinascidine 770|||Et-770；Ecteinascidine 770|||Et-770
Ecteinascidin 770 (ET-770) inhibits U373MG cells and is a 1,2,3, 4-tetrahydroisoquinoline alkaloid with strong anticancer activity.IC50 is 4.83 nM.
价 格：￥电议型 号：T11150产 地：中国大陆
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T1115Doxylamine succinate；琥珀酸多西拉敏Decapryn；琥珀酸多西拉敏|||Decapryn
Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate (Decapryn) competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of the gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug a
价 格：￥电议型 号：T1115产 地：中国大陆
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T11149Ecopladib；化合物EcopladibPLA 725；PLA 725
Ecopladib (PLA 725) is a sub-micromolar inhibitor of cytosolic phospholipase A2α (cPLA2α), with IC50s of 0.15 μM and 0.11 μM in the GLU micelle and rat whole blood assays, respectively.
价 格：￥电议型 号：T11149产 地：中国大陆
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T11148Ecastolol；依卡洛尔Ecastolol
Ecastolol has anti-angina activity and is an adrenergic receptor antagonist.
价 格：￥电议型 号：T11148产 地：中国大陆
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T11147EC5026；化合物EC5026BPN-19186；BPN-19186
EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
价 格：￥电议型 号：T11147产 地：中国大陆
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T11146EC359；化合物EC359EC-359；EC-359
EC359 is a potent and selective inhibitor of leukemia inhibitory factor receptor (LIFR), a potent inhibitor with anticancer activity, blocks LIF/LIFR interaction, and can be used in the study of leukemia and endometrial cancer.
价 格：￥电议型 号：T11146产 地：中国大陆
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T11144EC0488；化合物 T11144EC0488
EC0488 was used to synthesize EC0531, which has folic acid receptor specificity and anti-tumor activity.
价 格：￥电议型 号：T11144产 地：中国大陆
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T11143EB-47；化合物EB-47EB-47
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.
价 格：￥电议型 号：T11143产 地：中国大陆
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T11142EACC；化合物EACCEACC
EACC, a reversible autophagy inhibitor, selectively impedes Stx17, an autophagosome-specific SNARE, from translocating, hence obstructing the fusion between autophagosomes and lysosomes. This compound effectively halts autophagic flux.
价 格：￥电议型 号：T11142产 地：中国大陆
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T11141E64FC26；化合物E64FC26E64FC26
E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer.
价 格：￥电议型 号：T11141产 地：中国大陆
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T11140E6130；化合物 T11140E6130
E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.
价 格：￥电议型 号：T11140产 地：中国大陆
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T1114Ciclopirox olamine；环吡酮乙醇胺盐Ciclopirox ethanolamine；环吡酮乙醇胺盐|||环吡司胺|||Ciclopirox ethanolamine
Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
价 格：￥电议型 号：T1114产 地：中国大陆
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T11139(E/Z)-BCI；化合物(E/Z)-BCINSC 150117；NSC 150117
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS production in macrophage cells by activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
价 格：￥电议型 号：T11139产 地：中国大陆
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T11138LLHF-535；化合物LHF-535LHF-535
LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.
价 格：￥电议型 号：T11138L产 地：中国大陆
