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T3567617β-hydroxy Exemestane;17β-hydroxy Exemestane17β-hydroxy Exemestane
17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (IC50 = 69 nM using human placental microsomes) and an androgen receptor (AR) agonist (IC50 = 39.6 nM) that is selective for AR over estrogen receptor α (ERα; IC50 = 21.2 μM). It stimulates growth of AR- and ERα-positive MCF-7 (EC50 = 2.7 μM) and T47D breast cancer cells (EC50s =
价 格:¥电议型 号:T35676产 地:中国大陆
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T354821-Palmitoyl-2-hydroxy-sn-glycero-3-PE;1-Palmitoyl-2-hydroxy-sn-glycero-3-PE1-Palmitoyl-2-hydroxy-sn-
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-
价 格:¥电议型 号:T35482产 地:中国大陆
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T35126WE 1073;化合物 T35126WE-1073|||WE1073;WE-1073|||WE1073
WE 1073 is a biochemical.
价 格:¥电议型 号:T35126产 地:中国大陆
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T35125We 1008;化合物 T35125We1008|||We -;We1008|||We -
We 1008 is a biochemical.
价 格:¥电议型 号:T35125产 地:中国大陆
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T34911400W dihydrochloride;化合物1400W dihydrochloride1400W 2HCl|||N-(3-(Aminomethyl)benzyl)acetamidine;1400
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
价 格:¥电议型 号:T3491产 地:中国大陆
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T322516,17-Epoxy-21-acetoxypregnenolone;化合物16,17-Epoxy-21-acetoxypregnenolone16,17-Epoxy-21-acetoxypregne
16,17-Epoxy-21-acetoxypregnenolone serves as an intermediate in pharmaceutical applications.
价 格:¥电议型 号:T3225产 地:中国大陆
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T3224TBA-7371;化合物DprE1-IN-1AZ 7371|||DprE1-IN-1;AZ 7371|||DprE1-IN-1
TBA-7371 (DprE1-IN-1) is a potent inhibitor of DprE1 and PDE6.
价 格:¥电议型 号:T3224产 地:中国大陆
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T32177Ioforminol;化合物 T32177GE-145|||GE145|||AN 113111|||AN113111|||AN-113111|||GE 145;GE-145|||GE145|||AN
Ioforminol, also known as GE-145 and AN-113111, is a new low-osmolar dimeric radiographic contrast agent. GE-145 exhibits similar preclinical properties to other dimeric radiographic contrast media. In addition, the low osmolality enables an iso-osmolar formulation containing a significantly higher concentration of electrolytes than Visipaque.
价 格:¥电议型 号:T32177产 地:中国大陆
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T3203Methyl 13-cis-4-Oxoretinoate;化合物Methyl 13-cis-4-Oxoretinoate13-cis-4-Oxo-retinoic acid Methyl Ester|
Methyl 13-cis-4-Oxoretinoate (13-cis-4-Oxo-retinoic acid Methyl Ester) is a retinoic acid metabolite in neuroblastoma.
价 格:¥电议型 号:T3203产 地:中国大陆
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T31731Evodenoson;依沃迪松DE 112|||DE-112|||ATL 313|||DE112|||ATL313|||ATL-313;DE 112|||DE-112|||ATL 313|||DE11
Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumors.
价 格:¥电议型 号:T31731产 地:中国大陆
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T3162IDE1;化合物IDE1IDE1
IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM in vitro) by activating the TGF-β signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube, contributing to its formation.
价 格:¥电议型 号:T3162产 地:中国大陆
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T31469Dihydroergostin;化合物 T31469DE145|||DE-145|||DE 145;DE145|||DE-145|||DE 145
Dihydroergostin is a ergot alkaloid that exhibits potential neuroprotective properties.
价 格:¥电议型 号:T31469产 地:中国大陆
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T3109SP600125;化合物Pyrazolanthrone1PMV|||JNK Inhibitor II|||Nsc75890|||Pyrazolanthrone;1PMV|||JNK Inhibitor
SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
价 格:¥电议型 号:T3109产 地:中国大陆
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T31065CP-5609;化合物 T31065CP5609|||ME1036|||UNII-33501R83O2|||ME 1036|||ME-1036|||CP 5609|||ME 1036;ME1036;C
CP-5609 is a new class of carbapenems with enhanced antimicrobial activity.
价 格:¥电议型 号:T31065产 地:中国大陆
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T2S1702(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one1,7-双苯-5-羟基-6-庚烯-3-酮1,7-双苯-5-羟基-6-庚烯-3-酮|||(5R)-trans-1
(5R,6E)-5-Hydroxy-1,7-diphenyl-6-hepten-3-one ((5R)-trans-1,7-diphenyl-5-hydroxy-6-hept) has antioxidant activity.
价 格:¥电议型 号:T2S1702产 地:中国大陆
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T29908Alprostadil ethyl ester;化合物 T29908Prostaglandin E1 ethyl ester|||PGE1 ethyl ester;Prostaglandin E1 e
Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.
价 格:¥电议型 号:T29908产 地:中国大陆
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T29907Alprostadil sodium;化合物 T29907PGE1 sodium salt|||Prostaglandin E1 sodium;PGE1 sodium salt|||Prostagla
Alprostadil sodium is a prostaglandin receptor ligand with Ki values of 36, 10, 1.1, 2.1, and 33 nM for EP1, EP2, EP3, EP4, and IP, respectively, in mice.It induces vasodilatation and inhibits platelet aggregation, and it can be used as a vasodilator for the study of peripheral vascular disease.
价 格:¥电议型 号:T29907产 地:中国大陆
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T29693Aftobetin HCl;化合物 T29693ANCA11|||NCE 11|||NCE11|||NCE-11;ANCA11|||NCE 11|||NCE11|||NCE-11
Aftobetin, also known as ANCA11 and NCE-11, is a novel amyloid–binding compound applied topically in the form of an ophthalmic ointment. Aftobetin may be of useful as an aid in the diagnosis Alzheimer´s disease.
价 格:¥电议型 号:T29693产 地:中国大陆
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T29166XIE18-6;化合物 T29166XIE186;XIE186
XIE18-6, a novel INK4C inhibitor, specifically blocks the bioactivity of p18 protein and promotes human and murine hematopoietic stem cell ex vivo expansion.
价 格:¥电议型 号:T29166产 地:中国大陆
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T28350PDE10A-IN-8;化合物 T28350PDE10A-IN8|||PDE10A-IN 8;PDE10A-IN8|||PDE10A-IN 8
PDE10A-IN-8 is a potent inhibitor of PDE10A.
价 格:¥电议型 号:T28350产 地:中国大陆