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T6717Vanillininhibit,Vanillin,Inhibitor,Endogenous Metabolite
Vanillin is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.Vanillin can reversibly and non-competitively inhibit the cellulase activity at appropriate concentrations and the value of IC50 was estimated to be 30 g/L.Vanillin protects KSC from UVB irradiation and its effects may occur through the suppression of downstream step of MDM2 in UVB irradiation-induced p53 activation. Vanillin also inhibits yeast growth and fermentation.
价 格:¥电议型 号:T6717产 地:中国大陆
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T9531MRT-14Inhibitor,Smo,Hedgehog,Smoothened,cancer,MRT 14,inhibit,MRT14,MRT-14
MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.
价 格:¥电议型 号:T9531产 地:中国大陆
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T28036MI-2-2cell proliferation,inhibit,menin-MLL interaction,Epigenetic Reader Domain,Inhibitor,Hoxa9 expr
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
价 格:¥电议型 号:T28036产 地:中国大陆
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T7093RafoxanideHemonchus,Rafoxanide,energy metabolism,inhibit,antiparasitic,Parasite,Fasciola,Estrus ovis
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
价 格:¥电议型 号:T7093产 地:中国大陆
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T7297KG-501Epigenetic Reader Domain,inhibit,Inhibitor,KG 501,Naphthol AS-E,KG501,KG-501
KG-501 is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).
价 格:¥电议型 号:T7297产 地:中国大陆
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T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE
Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.
价 格:¥电议型 号:T7846产 地:中国大陆
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TWS2045Bruceine DParasite,Notch,Apoptosis,Bruceine D,Inhibitor,inhibit
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
价 格:¥电议型 号:TWS2045产 地:中国大陆
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T6940PHA-767491 hydrochloridePHA767491,PHA 767491,inhibit,CAY-10572,Cyclin dependent kinase,CDK,CAY 10572
PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
价 格:¥电议型 号:T6940产 地:中国大陆
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T8419XP-59XP 59,XP59,inhibit,Inhibitor,SARS-CoV,XP-59,SARS coronavirus
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
价 格:¥电议型 号:T8419产 地:中国大陆
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T7117Sapropterin dihydrochloride(6R)-BH4,Sapropterin,Inhibitor,inhibit,Sapropterin dihydrochloride
Sapropterin dihydrochloride is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.
价 格:¥电议型 号:T7117产 地:中国大陆
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TN2260Taxifolin 7-O-rhamnosideInhibitor,Taxifolin 7Orhamnoside,Taxifolin 7 O rhamnoside,inhibit
Taxifolin 7-O-rhamnoside is a natural product from Hypericum japonicum.
价 格:¥电议型 号:TN2260产 地:中国大陆
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T6S1572Sauchinoneantioxidant,LPS,Diastereomeric,TNF-α,iNOS,anti-inflammatory,lignan,COX-2,inhibit,Nuclear f
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhi
价 格:¥电议型 号:T6S1572产 地:中国大陆
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T8478SC-43antiproliferative,Inhibitor,SC-43,SHP-1,PTPN6,Phosphatase,Apoptosis,caspase-3,SC 43,anti-fibrot
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
价 格:¥电议型 号:T8478产 地:中国大陆
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T80582-Methyl-4-pentenoic Acidinhibit,Inhibitor,2 Methyl 4 pentenoic Acid,2Methyl4pentenoic Acid
2-Methyl-4-pentenoic acid is a branched-chain fatty acid.
价 格:¥电议型 号:T8058产 地:中国大陆
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TN2272Tigloylgomisin Hinhibit,Inhibitor,Tigloylgomisin H
Tigloylgomisin H significantly induces quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a novel monofunctional inducer that specifically upregulates phase II enzymes through the Nrf2-ARE pathway and can be used in liver cancer prevention studies.
价 格:¥电议型 号:TN2272产 地:中国大陆
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T9584UNC6934Inhibitor,UNC6934,Histone Methyltransferase,inhibit,UNC 6934,UNC-6934
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
价 格:¥电议型 号:T9584产 地:中国大陆
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T6S0078Oxypeucedanin hydrateInhibitor,inhibit,Oxypeucedanin,(+)-Oxypeucedanin,Oxypeucedanin hydrate,D. anet
1. Oxypeucedanin hydrate has antioxidant activity. 2. Oxypeucedanin hydrate is an antimutagenic agent. 3. Oxypeucedanin hydrate exhibits carbohydrate metabolizing enzymes inhibitory effect.
价 格:¥电议型 号:T6S0078产 地:中国大陆
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T6778BDA-366Inhibitor,BDA-366,Antitumor,Bcl-2 Family,inhibit,Bcl2-BH4 domain,Anticancer,BDA 366,Antiapopt
BDA-366 is a potent Bcl2 antagonist, binding Bcl2-BH4 domain with high affinity and selectivity (Ki = 3.3 nM). BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells[1].
价 格:¥电议型 号:T6778产 地:中国大陆
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TP1240Adrenocorticotropic Hormone (ACTH) (18-39), human TFAinhibit,Adrenocorticotropic Hormone (ACTH) (18-
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, it is is produced in the melanotrophs of the intermediate lobe of the pituitary.
价 格:¥电议型 号:TP1240产 地:中国大陆
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T3899Calceolarioside BInhibitor,inhibit,Calceolarioside B
Calceolarioside B displays inhibition of aromatase. Calceolarioside B displays inhibition of human recombinant PKCalpha.
价 格:¥电议型 号:T3899产 地:中国大陆