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T7318Elimusertib；化合物BAY-1895344BAY-1895344；BAY-1895344
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride.
价 格：￥电议型 号：T7318产 地：中国大陆
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T72604Multi-kinase-IN-1；化合物 Multi-kinase-IN-1Multi-kinase-IN-1
Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis. It is under investigation for its potential application in treating colorectal cancer.
价 格：￥电议型 号：T72604产 地：中国大陆
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T72013Epigenetic Multiple Ligand；化合物 Epigenetic Multiple LigandEpigenetic Multiple Ligand
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing either apoptosis or granulocytic differentiation.
价 格：￥电议型 号：T72013产 地：中国大陆
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T71734Muraglitazar glucuronide；化合物 Muraglitazar glucuronideMuraglitazar glucuronide
Muraglitazar glucuronide is a Peroxime Proliferator Activated (PPAR) Agonist that has glucose- and lipid-lowering activities.
价 格：￥电议型 号：T71734产 地：中国大陆
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T71635Murayaquinone；化合物 MurayaquinoneMurayaquinone
Murayaquinone is a hepatitis C virus proteinase inhibitor and small molecule antagonist of the oncogenic Tcf/β-catenin protein complex.
价 格：￥电议型 号：T71635产 地：中国大陆
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T7154trans-trans-Muconic acid；反式,反式-1,3-丁二烯-1,4-二羧酸trans-trans-Muconic acid
trans-trans-Muconic acid is a urinary metabolite of benzene.
价 格：￥电议型 号：T7154产 地：中国大陆
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T71535GlmU-IN-5175178；化合物 GlmU-IN-5175178GlmU-IN-5175178
GlmU-IN-5175178 is an inhibitor of the acetyltransferase activity of Escherichia coli N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU).
价 格：￥电议型 号：T71535产 地：中国大陆
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T71500Palifosfamide tromethamine；化合物 Palifosfamide-TrisIPM tromethamine|||Isophosphoramide mustard trometh
Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, inhibiting DNA replication and inducing cell death. Palifosfamide (tromethamine) boasts reduced toxicity in comparison to ifosfamide.
价 格：￥电议型 号：T71500产 地：中国大陆
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T71059Ranitidine bismuth citrate；化合物 Ranitidine bismuth citrateIST 622；IST 622|||雷尼替丁枸橼酸盐
Ranitidine bismuth citrate, an orally administered Histamine H2-receptor antagonist, demonstrates a potent inhibitory concentration (IC 50) of 3.3 μM and exhibits high selectivity towards SARS-CoV-2-infected cells. It is widely utilized as an anti-Helicobacter pylori agent, exhibiting a minimum inhibitory concentration (MIC 90) value of 16 ng/L.
价 格：￥电议型 号：T71059产 地：中国大陆
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T71048Tacrolimus anhydrous 8-epimer；化合物 Tacrolimus anhydrous 8-epimerTacrolimus anhydrous 8-epimer
Tacrolimus anhydrous 8-epimer is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.
价 格：￥电议型 号：T71048产 地：中国大陆
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T70899Vidofludimus hemicalcium；化合物 Vidofludimus calcium4sc-101 hemicalcium|||SC12267 hemicalcium|||4sc-101
Vidofludimus hemicalcium (4sc-101; SC12267) is an orally active compound that acts as a dihydroorotate dehydrogenase (DHODH) inhibitor and serves as a novel modulator of the farnesoid X receptor (FXR). This immunomodulatory agent is utilized in the research of autoimmune disorders, including inflammatory bowel disease (IBD), and is explored for its potential in fatty liver disease research through FXR targeting.
价 格：￥电议型 号：T70899产 地：中国大陆
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T70872Smurf1 inhibitor 1；化合物 Smurf1 inhibitor 1Smurf1 inhibitor 1
Smurf1 inhibitor 1 is a inhibitor that promotes bone formation.
价 格：￥电议型 号：T70872产 地：中国大陆
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T70377-Acetoxy-4-methylcoumarin；7-乙酰氧基-4-甲基香豆素MU-Ac；7-乙酰氧基-4-甲基香豆素|||MU-Ac
7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin, the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The co
价 格：￥电议型 号：T7037产 地：中国大陆
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T70229Laromustine；化合物 LaromustineLaromustine
Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair.
价 格：￥电议型 号：T70229产 地：中国大陆
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T70190Tinostamustine HCl；化合物 Tinostamustine HClTinostamustine HCl
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents.
价 格：￥电议型 号：T70190产 地：中国大陆
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T70128Olmutinib hydrochloride；化合物 Olmutinib hydrochlorideOlmutinib hydrochloride
Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor, used in the treatment of T790M mutation positive non-small cell lung cancer. Olmutinib covalently binds a cysteine residue near the kinase domain of mutant EGFRs to prevent phosphorylation of the receptor. EGFRs are frequently over-expressed in lung cancer and contribute to activation of the phosphoinositide 3-kinase and mitogen-activated protein kinase pathways which both p
价 格：￥电议型 号：T70128产 地：中国大陆
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T70107Olcorolimus；化合物 OlcorolimusOlcorolimus
Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5
价 格：￥电议型 号：T70107产 地：中国大陆
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T6S1597Mulberroside A桑皮苷 A桑皮苷 A|||桑皮苷A
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of melanogenesis. 3. Mulberroside A has anti-inflammatory antiapoptotic effects. by decreasing the expressions of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and inhibiting the activation of NALP3, caspase-1, and nuclear factor-κB and the phosphorylation of extra
价 格：￥电议型 号：T6S1597产 地：中国大陆
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T6S0619Pachymic acid；茯苓酸3-O-Acetyltumulosic acid；3-O-Acetyltumulosic acid|||茯苓酸
Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.
价 格：￥电议型 号：T6S0619产 地：中国大陆
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T69980XMU-MP-2；化合物XMU-MP-2XMU-MP-2
XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft model.
价 格：￥电议型 号：T69980产 地：中国大陆
