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T18673(S,R,S)-AHPC-O-Ph-PEG1-NH2；化合物 T18673VH032-O-Ph-PEG1-NH2；VH032-O-Ph-PEG1-NH2
(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) serves as an E3 ligase ligand-linker conjugate, integrating a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is utilized in PROTAC EED degrader-1, a PROTAC that targets EED with a potency (pKD) of 9.02[1].
价 格：￥电议型 号：T18673产 地：中国大陆
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T18672(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc；化合物 T18672VH032-O-Ph-PEG1-NH-Boc；VH032-O-Ph-PEG1-NH-Boc
(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate, specifically designed for targeting the EED protein in PROTAC applications[1].
价 格：￥电议型 号：T18672产 地：中国大陆
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T18671(S,R,S)-AHPC-Me-C7 ester；化合物 T18671(S,R,S)-AHPC-Me-C7 ester
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
价 格：￥电议型 号：T18671产 地：中国大陆
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T18670(S,R,S)-AHPC-Me-C5-COOH；化合物 T18670(S,R,S)-AHPC-Me-C5-COOH
(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate consisting of a VHL ligand and a linker. It finds application in PROTAC DT2216[1].
价 格：￥电议型 号：T18670产 地：中国大陆
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T18669(S,R,S)-AHPC-Me-C10-NH2；化合物 T18669(S,R,S)-AHPC-Me-C10-NH2
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in PROTAC MS432[1].
价 格：￥电议型 号：T18669产 地：中国大陆
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T18668(S,R,S)-AHPC-Me-C10-Br；化合物 T18668(S,R,S)-AHPC-Me-C10-Br
(S,R,S)-AHPC-Me-C10-Br is a chemically synthesized conjugate that functions as a ligand-linker for E3 ligases. This compound incorporates a VHL E3 ligase linker and MS432, derived from the MEK1/2 inhibitor PD0325901[1].
价 格：￥电议型 号：T18668产 地：中国大陆
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T18667(S,R,S)-AHPC-C5-COOH；化合物 T18667VH032-C5-COOH；VH032-C5-COOH
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized conjugate designed for E3 ligase ligand-linker applications, combining the VH032 VHL-based ligand with a linker for PROTAC development. VH-032 acts as a selective and potent VHL/HIF-1α interaction inhibitor, with a dissociation constant (Kd) of 185 nM, offering potential in anemia and ischemic diseases research[1].
价 格：￥电议型 号：T18667产 地：中国大陆
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T18666(S,R,S)-AHPC-C4-NH2；化合物 T18666VH032-C4-NH2；VH032-C4-NH2
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specifically designed for EED-Targeted PROTAC[1].
价 格：￥电议型 号：T18666产 地：中国大陆
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T18665(S,R,S)-AHPC-C4-NH2 dihydrochloride化合物 T18665VH032-C4-NH2 dihydrochloride
(S,R,S)-AHPC-C4-NH2 dihydrochloride is a chemically derived E3 ligase ligand-linker conjugate, consisting of the (S,R,S)-AHPC VHL ligand and a linker specifically designed for EED-Targeted PROTAC[1].
价 格：￥电议型 号：T18665产 地：中国大陆
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T18664(S,R,S)-AHPC-C3-NH2；化合物 T18664VH032-C3-NH2；VH032-C3-NH2
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component in the synthesis of various PROTACs, including UNC6852. UNC6852 is a bivalent chemical degrader specifically targeting EED [1].
价 格：￥电议型 号：T18664产 地：中国大陆
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T18663(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)；化合物 T18663(S,R,S)-AHPC-C3-NH2 TFA|||VH032-C3-NH2 TF
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, such as UNC6852. UNC6852 is an EED-targeted bivalent chemical degrader[1].
价 格：￥电议型 号：T18663产 地：中国大陆
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T18662(S,R,S)-AHPC-C2-PEG4-N3；化合物 T18662VH032-C2-PEG4-N3；VH032-C2-PEG4-N3
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate combining the (S,R,S)-AHPC-based VHL ligand with a 4-unit polyethylene glycol (PEG) linker, employed in PROteolysis TAgeting Chimera (PROTAC) technology. This compound facilitates the creation of vRucaparib-TP4, a potent PARP1 degrader demonstrating a half-maximal degrading concentration (DC50) of 82 nM[1].
价 格：￥电议型 号：T18662产 地：中国大陆
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T18661(S,R,S)-AHPC-C10-NH2 dihydrochloride；(S,R,S)-AHPC-C10-NH2二盐酸盐VH032-C10-NH2 dihydrochloride|||VH032-l
(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].
价 格：￥电议型 号：T18661产 地：中国大陆
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T18660(S,R,S)-AHPC-amido-C5-acid；化合物 T18660(S,R,S)-AHPC-amido-C5-acid
(S,R,S)-AHPC-amido-C5-acid is a chemical compound that contains a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. It can be utilized in the design of XY028-133[1].
价 格：￥电议型 号：T18660产 地：中国大陆
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T18640(S,R,S)-AHPC-C4-NH2 hydrochloride；化合物 (S,R,S)-AHPC-C4-NH2 hydrochlorideVH032-C4-NH2 hydrochloride|||
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker.
价 格：￥电议型 号：T18640产 地：中国大陆
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T18559PPC-NHS ester；化合物 T185592,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate；2,5-Dioxopyrrol
PPC-NHS ester is a cleavable linker vital in ADC synthesis. PPC-NHS ester joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格：￥电议型 号：T18559产 地：中国大陆
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T18558PPC-NB；化合物 T18558PPC-NB
PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC)[1].
价 格：￥电议型 号：T18558产 地：中国大陆
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T18530PDP-C1-Ph-Val-Cit；化合物 T18530PDP-C-1-Ph-Val-Cit|||PDP C1 Ph Val Cit|||PDPC1PhValCit|||PDP-C1-Ph-Val-C
PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T18530产 地：中国大陆
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T18525PC SPDP-NHS carbonate ester；化合物 T18525PC SPDP-NHS carbonate ester
PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18525产 地：中国大陆
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T18524PC-PEG11-Azide；化合物 T18524PC-PEG11-Azide
PC-PEG11-Azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18524产 地：中国大陆
