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T62725IDH1 Inhibitor 5；化合物 IDH1 Inhibitor 5IDH1 Inhibitor 5
IDH1 Inhibitor 5 (compound 2) is an inhibitor of IDH1 (isocitrate dehydrogenase 1), which inhibits MOG cells (IC50: 64.4 nM) and wild-type IDH1 glioma cells expressing exogenous mutant IDH1 R132H protein (IC50: 34.9 nM).
价 格：￥电议型 号：T62725产 地：中国大陆
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T62724AQX-435；化合物 AQX-435AQX-435
AQX-435 is a potent activator of SHIP1 (SH2 domain-containing inositol-5′-phosphatase 1). AQX-435 decreases B-cell receptor (BCR) downstream PI3K activity, induces apoptosis in malignant B cells, and exhibits inhibitory effects on lymphoma growth.
价 格：￥电议型 号：T62724产 地：中国大陆
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T62723RIPK1-IN-12；化合物 RIPK1-IN-12RIPK1-IN-12
RIPK1-IN-12 is a potent inhibitor of RIPK1, which exhibits an inhibitory effect on necroptosis in human and mouse cells with EC50 values of 1.6 and 2.9 nM, respectively.
价 格：￥电议型 号：T62723产 地：中国大陆
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T62722SC13；化合物 SC13SC13
SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.
价 格：￥电议型 号：T62722产 地：中国大陆
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T62721CPI-1612；化合物 CPI-1612CPI-1612
CPI-1612 is a potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor that acts on EP300 HAT (IC50: 8.1 nM). CPI-1612 exhibits anticancer effects.
价 格：￥电议型 号：T62721产 地：中国大陆
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T62720CBP/p300-IN-18；化合物 CBP/p300-IN-18CBP/p300-IN-18
CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).
价 格：￥电议型 号：T62720产 地：中国大陆
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T6272Fosbretabulin Disodium；福他布林Combretastatin A4 Phosphate|||CA 4DP|||CA 4P|||Combretastatin A4 disodium
Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibits the polymerization of tubulin (IC50: 2.4 μM), and also disrupts tumor vasculature.
价 格：￥电议型 号：T6272产 地：中国大陆
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T62719AChE/BACE1/GSK3β-IN-1；化合物 AChE/BACE1/GSK3β-IN-1AChE/BACE1/GSK3β-IN-1
AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β. AChE/BACE1/GSK3β-IN-1 can be used to study Alzheimer´s disease (AD).
价 格：￥电议型 号：T62719产 地：中国大陆
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T62718RSK2-IN-3；化合物 RSK2-IN-3RSK2-IN-3
RSK2-IN-3 (Compound 26) is a covalent, reversible inhibitor of RPS6KA3 (RSK2) kinase.
价 格：￥电议型 号：T62718产 地：中国大陆
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T62717A2AAR/HDAC-IN-2；化合物 A2AAR/HDAC-IN-2A2AAR/HDAC-IN-2
A2AAR/HDAC-IN-2 is a potent dual A2AAR/HDAC inhibitor.A2AAR/HDAC-IN-2 shows good affinity for A2AAR (Ki:10.3 nM) and inhibits HDAC1 well (IC50:18.5 nM). A2AAR/HDAC-IN-2 can be used in anti-tumour studies.
价 格：￥电议型 号：T62717产 地：中国大陆
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T62716BTK-IN-10；化合物 BTK-IN-10BTK-IN-10
BTK-IN-10 is a potent inhibitor of BTK, acting on wild-type BTK (IC50<5 nM) or mutant BTK (C481S) (IC50<5 nM).
价 格：￥电议型 号：T62716产 地：中国大陆
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T62715BPTF-IN-1；化合物 BPTF-IN-1BPTF-IN-1
BPTF-IN-1 (compound AU1) is a selective BPTF bromodomain inhibitor (Kd: 2.8 μM) that is more selective for BPTF than for the BRD4 bromodomain.BPTF-IN-1 has an antimalarial effect.
价 格：￥电议型 号：T62715产 地：中国大陆
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T62713Y08175；化合物 Y08175Y08175
Y08175 is a potent inhibitor of CBP Bromodomain. y08175 has an IC50 of 37 and 178.15 nM against CBP in the AlphaScreen and HTRF assays, respectively. y08175 can be used to study prostate cancer.
价 格：￥电议型 号：T62713产 地：中国大陆
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T62712SOS1-IN-10；化合物 SOS1-IN-10SOS1-IN-10
SOS1-IN-10 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 13 nM).
价 格：￥电议型 号：T62712产 地：中国大陆
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T62711OPC-14523 hydrochloride；OPC-14523 盐酸盐VPI 013 hydrochloride；VPI 013 hydrochloride
OPC-14523 hydrochloride (VPI 013 hydrochloride) is an orally active and potent sigma and 5-HT1A receptor agonist with antidepressant activity for the study of neurological disorders.
价 格：￥电议型 号：T62711产 地：中国大陆
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T62710Antitrypanosomal agent 6；化合物 Antitrypanosomal agent 6Antitrypanosomal agent 6
Antitrypanosomal agent 6 (compound 18a) is a potent antitrypanosomal agent showing good ADME properties. Antitrypanosomal agent 6 is more than twice as active as Nifurtimox against Trypanosoma brucei (T. brucei) with an IC50 of 0.47 μM. Antitrypanosomal agent 6 has a strong interaction with DNA and selectively binds AT-rich DNA.
价 格：￥电议型 号：T62710产 地：中国大陆
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T6271Tipifarnib；替吡法尼R115777|||Zarnestra|||IND 58359；替吡法尼|||R115777|||Zarnestra|||IND 58359
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.
价 格：￥电议型 号：T6271产 地：中国大陆
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T62709EBOV-GP-IN-1；化合物 EBOV-GP-IN-1EBOV-GP-IN-1
EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).
价 格：￥电议型 号：T62709产 地：中国大陆
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T62708HDAC-IN-37；化合物 HDAC-IN-37HDAC-IN-37
HDAC-IN-37 is a potent inhibitor of HDAC, acting on HDAC1 (IC50: 0.0551 μM), HDAC3 (IC50: 1.24 μM), HDAC8 (IC50: 0.948 μM) and HDAC6 (IC50: 34.2 μM). HDAC-IN-37 is able to slowly induce histone acetylation. HDAC-IN-37 prevents the transition from G1 to S phase and induces early apoptosis.
价 格：￥电议型 号：T62708产 地：中国大陆
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T62707Antimicrobial agent-4；化合物 Antimicrobial agent-4Antimicrobial agent-4
Antimicrobial agent-4 (compound 6a) is a potent antimicrobial agent with high activity against microbial pathogens. -4 exhibits a high binding capacity of 10.0 kcal/mol for the target enzyme.
价 格：￥电议型 号：T62707产 地：中国大陆
