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T74330hCAII-IN-6；化合物 hCAII-IN-6hCAII-IN-6
hCAII-IN-6 (Compound S-13), a potent inhibitor of human carbonic anhydrase II (hCA II) with a K i of 4.4 nM, also exhibits inhibitory activity against other hCA isoforms, namely I, IV, and IX, with K i values of 9.2 nM, 480.2 nM, and 14.7 nM, respectively. It is utilized in glaucoma research [1].
价 格：￥电议型 号：T74330产 地：中国大陆
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T74142Angiotensin II human TFA；化合物 Angiotensin II human TFAAngiotensin II human TFA
Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). It not only prompts sympathetic nervous stimulation, aldosterone biosynthesis, and renal effects but also fosters growth in vascular smooth muscle cells and boosts collagen type I and III synthesis in fibrob
价 格：￥电议型 号：T74142产 地：中国大陆
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T74069Fluorescein-diisobutyrate-6-amide；化合物 Fluorescein-diisobutyrate-6-amideFluorescein-diisobutyrate-6-a
Fluorescein-diisobutyrate-6-amide, a powerful inducer of ferroptosis, shows promise for cancer research applications [1].
价 格：￥电议型 号：T74069产 地：中国大陆
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T74016Trityl olmesartan medoxomil impurity III；化合物 Trityl olmesartan medoxomil impurity IIITrityl olmesart
Trityl olmesartan medoxomil impurity III is a specific impurity found in trityl olmesartan medoxomil, which serves as an intermediate in the synthesis of Olmesartan medoxomil [1].
价 格：￥电议型 号：T74016产 地：中国大陆
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T73900(±)-Alliin；化合物 (±)-Alliin(±)-Alliin
(±)-Alliin, the principal active component in garlic, functions as a potential inhibitor of SARS-CoV-2´s main protease (Mpro) [1].
价 格：￥电议型 号：T73900产 地：中国大陆
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T7390DMAT；2-二甲基氨基-4,5,6,7-四溴苯并咪唑Casein kinase II Inhibitor|||CK2 Inhibitor；Casein kinase II Inhibitor|||2
DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).
价 格：￥电议型 号：T7390产 地：中国大陆
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T73863PPACK II；化合物 PPACK IIPPACK II
PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .
价 格：￥电议型 号：T73863产 地：中国大陆
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T73177hCAII-IN-9；化合物hCAII-IN-9hCAII-IN-9
hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCAII-IN-9 is not blood-brain barrier permeable.
价 格：￥电议型 号：T73177产 地：中国大陆
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T73033TRK II-IN-1；化合物 TRK II-IN-1TRK II-IN-1
TRK II-IN-1 is a potent type II inhibitor of tropomyosin receptor kinases (TRK), demonstrating inhibitory half-maximal inhibitory concentrations (IC50s) of 3.3, 6.4, 4.3, and 9.4 nM against TRKA, TRKB, TRKC, and the mutant TRKA G667C, respectively. Additionally, this compound exhibits IC50 values of 1.3 nM against FLT3, 9.9 nM against RET, and 71.1 nM against VEGFR2. TRK II-IN-1 primarily serves as a research tool for studying TRK-driven cancers [1].
价 格：￥电议型 号：T73033产 地：中国大陆
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T72840hCAIX/XII-IN-6；化合物 hCAIX/XII-IN-6hCAIX/XII-IN-6
hCAIX/XII-IN-6, an orally active carbonic anhydrase (CA) inhibitor, targets human CA isoforms hCA I, II, IV, IX, and XII with inhibition constants (K i) of 6697 nM, 2950 nM, 4093 nM, 4.1 nM, and 7.7 nM, respectively. This compound is utilized in rheumatoid arthritis (RA) research.
价 格：￥电议型 号：T72840产 地：中国大陆
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T72586Lck Inhibitor III；化合物 Lck Inhibitor IIILck Inhibitor III
Lck Inhibitor III, a potent inhibitor of Lck, exhibits an IC50 value of 867 nM. Additionally, this compound effectively inhibits IL-2 synthesis in Jurkat cells, demonstrating an IC50 of 1.270 μM.
价 格：￥电议型 号：T72586产 地：中国大陆
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T72289Type II TRKu00A0inhibitor 1；化合物 Type II TRKu00A0inhibitor 1Type II TRKu00A0inhibitor 1
Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) fusion protein variants as well as the wild type. It demonstrates notable antiproliferative effects on Ba/F3 cells expressing CD74-TRKA G667C and ETV6-TRKC G696C, with half-maximal inhibitory concentrations (IC50s) of 6 nM and 1.7 nM, respectively [1].
价 格：￥电议型 号：T72289产 地：中国大陆
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T72281Caspase-9 Inhibitor III；化合物 Caspase-9 Inhibitor IIIAc-LEHD-cmk；Ac-LEHD-cmk
Caspase-9 Inhibitor III (Ac-LEHD-cmk), a caspase-9 inhibitor, exhibits protective effects against ischemia-reperfusion-induced myocardial injury.
价 格：￥电议型 号：T72281产 地：中国大陆
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T72157Topoisomerase II inhibitor 7；化合物 Topoisomerase II inhibitor 7Topoisomerase II inhibitor 7
Topoisomerase II inhibitor 7, a potent inhibitor of the topoisomerase II alpha subtype, exhibits an IC50 of 3.19 μM. It effectively induces cell cycle arrest and apoptosis.
价 格：￥电议型 号：T72157产 地：中国大陆
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T71780Diisopropylamine dichloroacetate；化合物 Diisopropylamine dichloroacetateDiisopropylamine dichloroacetat
Diisopropylamine dichloroacetate stimulates smooth muscle & strongly inhibits acetylcholinesterase activity.
价 格：￥电议型 号：T71780产 地：中国大陆
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T71620iBAP-II；化合物 iBAP-IIiBAP-II
iBAP-II represses neuroendocrine lineage-specific ASCL1/MYCL/E2F signaling in SCLC cell lines, and dramatically inhibits SCLC cell viability and tumor growth in vivo.
价 格：￥电议型 号：T71620产 地：中国大陆
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T71559Melanotan II acetate；化合物 Melanotan II acetateMelanotan II acetate
Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases in sensory nerve conduction velocity. Melanotan II acetate increases oxygen consumption and protein levels of uncoupling protein 1 (UCP1) in brown adipose tissue homogenates and decreases food intake, body weight, and serum levels of leptin, glucose, insulin, and cholesterol.
价 格：￥电议型 号：T71559产 地：中国大陆
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T7155JH-II-127；化合物JH-II-127JH-II-127
JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, G2019S LRRK2 and A2016T LRRK2 (IC50s = 6.6, 2.2, and 47.7 nM, respectively),
价 格：￥电议型 号：T7155产 地：中国大陆
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T71316ERK Inhibitor II (Negative control)；化合物 QUN-70738ERK Inhibitor II (Negative control)
ERK Inhibitor II (Negative control) effectively blocks extracellular signal-regulated kinase (ERK) and interferes with insulin receptor activation, serving as a useful tool in diabetes research.
价 格：￥电议型 号：T71316产 地：中国大陆
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T70931SYK-IN-II；化合物 SYK-IN-IISYK-IN-II
SYK-IN-II is an inhibitor of the spleen tyrosine kinase (STK).
价 格：￥电议型 号：T70931产 地：中国大陆
