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T17975Fmoc-NH-pentanoic acid-NHS-SO3Na；化合物 T17975Fmoc-NH-pentanoic acid-NHS-SO3Na
Fmoc-NH-pentanoic acid-NHS-SO3Na is a PROTAC linker molecule derived from an alkyl chain. It possesses the ability to facilitate the synthesis of PROTACs[1].
价 格：￥电议型 号：T17975产 地：中国大陆
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T1797Cabozantinib S-malate；卡博替尼苹果酸盐Cabozantinib|||XL184|||Cabozantinib Malate；苹果酸卡博替尼|||Cabozantinib|||卡博
Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
价 格：￥电议型 号：T1797产 地：中国大陆
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T1796Otenabant hydrochloride；奥替那班Otenabant (CP-945598) HCl|||CP 945598 Hydrochloride|||Otenabant；奥替那班|||O
Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).
价 格：￥电议型 号：T1796产 地：中国大陆
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T1790Fosaprepitant dimeglumine；福沙吡坦二甲葡胺L785298|||MK-0517|||Fosaprepitant dimeglumine salt；福沙匹坦二甲葡胺|||L785
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
价 格：￥电议型 号：T1790产 地：中国大陆
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T1789Obeticholic Acid；奥贝胆酸INT-747|||6-Ethylchenodeoxycholic acid|||6-ECDCA；奥贝胆酸|||INT-747|||6-Ethylchenod
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist.
价 格：￥电议型 号：T1789产 地：中国大陆
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T1777Nintedanib；尼达尼布BIBF 1120|||Intedanib；BIBF 1120|||Intedanib|||尼达尼布
Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis.
价 格：￥电议型 号：T1777产 地：中国大陆
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T1774Intepirdine；化合物SB 742457RVT-101|||SB 742457|||GSK-742457；RVT-101|||SB 742457|||GSK-742457
Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer´s Disease.
价 格：￥电议型 号：T1774产 地：中国大陆
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T17731CL2A-SN-38；化合物CL2A-SN-38CL2A|||CL2A SN 38|||bystander effect|||SN-38|||antitumor|||CL2A-SN-38|||Inhi
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulf
价 格：￥电议型 号：T17731产 地：中国大陆
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T17692Boc-Val-Cit-PAB-PNP；化合物Boc-Val-Cit-PAB-PNPinhibit|||Antibody-drug conjugates linkers|||BocValCitPABP
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis.
价 格：￥电议型 号：T17692产 地：中国大陆
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T17473Azide-PEG9-amido-C4-Boc；化合物 T174735-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester；5-(Azide-PEG9
Azide-PEG9-amido-C4-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T17473产 地：中国大陆
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T1743Aprepitant；阿瑞匹坦MK-869|||MK-0869|||L-754030|||Aprepitant`；MK-869|||MK-0869|||阿瑞匹坦|||L-754030|||Aprepi
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
价 格：￥电议型 号：T1743产 地：中国大陆
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T173405-endo-BCN-pentanoic acid；化合物 T173405-endo-BCN-pentanoic acid
5-endo-BCN-pentanoic acid, an alkyl chain-based PROTAC linker, facilitates the synthesis of PROTACs[1].
价 格：￥电议型 号：T17340产 地：中国大陆
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T173354-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid；化合物 T173354-Methyl-4-(pyridin-2-yldisulfanyl)penta
4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T17335产 地：中国大陆
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T173344-Methyl-4-(methyldisulfanyl)pentanoic acid；化合物 T173344-Methyl-4-(methyldisulfanyl)pentanoic acid
4-Methyl-4-(methyldisulfanyl)pentanoic acid is an ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) that can be cleaved.
价 格：￥电议型 号：T17334产 地：中国大陆
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T173211,3-Dibromo-5,5-dimethylhydantoin；二溴海因1,3-Dibromo-5,5-dimethylhydantoin
1,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17321产 地：中国大陆
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T17265Ximelagatran；希美加群EXANTA|||H 376-95|||H37695|||H 376/95|||H-37695|||H 37695；EXANTA|||H 376-95|||H3769
Ximelagatran (H 376-95), a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the active agent melagatran in vivo.
价 格：￥电议型 号：T17265产 地：中国大陆
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T17261Xantocillin；黄青霉素Xantocillin
Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.
价 格：￥电议型 号：T17261产 地：中国大陆
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T17257WR99210化合物WR99210Antifolate|||Inhibitor|||Bacterial
WR99210 is a potent, orally available and less toxic dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 has good antiparasitic activity against P. vivax and P. falciparum strains (including P. falciparum strains resistant to Pyrimethamine ) and T. gondii.
价 格：￥电议型 号：T17257产 地：中国大陆
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T17256Wnt pathway activator 1；化合物Wnt pathway activator 1Wnt pathway activator 1
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM. Wnt pathway activator 1 is a potent Wnt activator for the treatment of androgenetic alopecia (AGA).
价 格：￥电议型 号：T17256产 地：中国大陆
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T17241Auglurant；化合物 T17241VU0424238；VU0424238
Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.
价 格：￥电议型 号：T17241产 地：中国大陆
