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T15483LEDGIN6;化合物 T15483HIV-1 integrase inhibitor 2;HIV-1 integrase inhibitor 2
HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
价 格:¥电议型 号:T15483产 地:中国大陆
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T1544Olsalazine disodium;奥沙拉秦钠Dipentum|||Olsalazine Sodium;Dipentum|||奥沙拉秦钠|||Olsalazine Sodium
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
价 格:¥电议型 号:T1544产 地:中国大陆
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T15387GLP-1R Antagonist 1;GLP-1R拮抗剂1GLP-1R Antagonist 1
GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).
价 格:¥电议型 号:T15387产 地:中国大陆
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T15370GANT 58;化合物GANT 58NSC 75503;4,44乔,4乔(2,3,4,5-Thiophentetrayl)tetrakis-pyridine|||NSC 75503
GANT 58 (NSC-75503) is a potent antagonist of Gli. Which inhibits GLI1-induced transcription (IC50: 5 μM).
价 格:¥电议型 号:T15370产 地:中国大陆
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T15368LGalantide acetate;化合物Galantide醋酸盐Galantide acetate(138579-66-5 Free base);Galantide acetate(138579-6
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide acetate dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide acetate appears to bind to a single population of SP receptors (KD~40 nM).
价 格:¥电议型 号:T15368L产 地:中国大陆
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T15368Galantide;化合物 T15368Galantide
Galantide is a reversible and non-specific antagonist of galanin receptor.
价 格:¥电议型 号:T15368产 地:中国大陆
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T15366Gabapentin enacarbil加巴喷丁酯XP-13512|||加巴喷丁酯
Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic drug gabapentin. Gabapentin enacarbil provides sustained dose-proportional exposure to gabapentin and predictable bioavailability.
价 格:¥电议型 号:T15366产 地:中国大陆
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T15341Fosnetupitant;化合物 T15341Pronetupitant;Pronetupitant
Fosnetupitant is a methylene phosphate prodrug of Netupitant. It has a pKi of 9.5 for the human NK1 receptor.
价 格:¥电议型 号:T15341产 地:中国大陆
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T15338Foropafant;福罗帕泛SR27417;SR27417|||福罗帕泛
Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM). Foropafant potently inhibits the PAF-induced aggregation of rabbit and human platelets.
价 格:¥电议型 号:T15338产 地:中国大陆
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T15317Fmoc-NH-PEG4-CH2CH2COOH;化合物 T15317Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid;Fmoc-15-amino-4
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T15317产 地:中国大陆
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T15278Fezolinetant;化合物FezolinetantESN-364;ESN-364
Fezolinetant (ESN-364) is an antagonist of the neurokinin 3 receptor (NK3R). It is used for the treatment of menopausal hot flushes.
价 格:¥电议型 号:T15278产 地:中国大陆
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T15274FEN1-IN-1;化合物FEN1-IN-1LNT-1;LNT-1
FEN1-IN-1 (LNT-1) is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions.
价 格:¥电议型 号:T15274产 地:中国大陆
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T15272Febantel;苯硫胍Febantel
Febantel is an anthelmintic. It is used for veterinary use on dogs, cats, cattle, sheep, goats, pig, and poultry against roundworms and tapeworms.
价 格:¥电议型 号:T15272产 地:中国大陆
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T15264Exicorilant;化合物 T15264CORT 125281;CORT 125281
Exicorilant is a selective and oral active glucocorticoid receptor (GR) antagonist (Ki: 7 nM) and it also has the potential to overcome adiposity, glucose intolerance, and dyslipidemia.
价 格:¥电议型 号:T15264产 地:中国大陆
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T15263Selisistat R-enantiomer;化合物EX-527 (R-enantioMer)EX-527 (R-enantiomer);EX-527 (R-enantiomer)
Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).
价 格:¥电议型 号:T15263产 地:中国大陆
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T15214Emicerfont;化合物 T15214GW876008;GW876008
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
价 格:¥电议型 号:T15214产 地:中国大陆
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T1519LRimonabant;利莫那班SR141716;SR141716|||利莫那班
Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue of effect is a reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. Rimonabant is approved in 38 countries including the E.U., Mexico, and Brazil. It was rejected for approval for use in the United States.
价 格:¥电议型 号:T1519L产 地:中国大陆
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T15198Edasalonexent;依达柰珍CAT-1004;CAT-1004
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.
价 格:¥电议型 号:T15198产 地:中国大陆
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T15134Dipraglurant;化合物 T15134ADX48621;ADX48621
Dipraglurant is a negative allosteric regulator (NAM) of blood-brain barrier transmissible mGluR5 with effective, selective and oral activity, with an IC50 value of 21 nM. Dipraglurant can treat levodopa-induced dyskinesia in Parkinson´s disease (PD-LID).
价 格:¥电议型 号:T15134产 地:中国大陆
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T15090Decoglurant;化合物DecoglurantRO4995819;RO4995819
Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.
价 格:¥电议型 号:T15090产 地:中国大陆