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T10831LCl-amidine hydrochloride;化合物Cl-amidine hydrochlorideCl-amidine hydrochloride
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 μM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro causing cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation. It improves survival in a murine sepsis model.
价 格:¥电议型 号:T10831L产 地:中国大陆
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T10831Cl-amidine;化合物 T10831Cl-amidine
Cl-amidine is an orally active inhibitor of peptidyl arginine deminase (PAD) (IC50s: 0.8 μM, 6.2 μM, and 5.9 μM for PAD1, PAD3, and PAD4). Cl-amidine induces apoptosis in cancer cells.
价 格:¥电议型 号:T10831产 地:中国大陆
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T10830CL 316243;化合物CL 316243CL 316243
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
价 格:¥电议型 号:T10830产 地:中国大陆
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T1083Theophylline;茶碱Theo-24|||1,3-Dimethylxanthine;Theo-24|||1,3-Dimethylxanthine|||茶碱
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3´, 5´-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
价 格:¥电议型 号:T1083产 地:中国大陆
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T10829CKI-7 free base;化合物 T10829CKI-7;CKI-7
CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
价 格:¥电议型 号:T10829产 地:中国大陆
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T10828CK2/PIM1-IN-1;化合物 T10828CK2/PIM1-IN-1
CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1 (IC50s: 3.787 μM and 4.327 μM). It is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions.
价 格:¥电议型 号:T10828产 地:中国大陆
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T10827CK2/ERK8-IN-1;化合物CK2/ERK8-IN-1TMCB;TMCB
CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 ?M) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 ?M, 11.9 ?M, and 15.25 ?M).
价 格:¥电议型 号:T10827产 地:中国大陆
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T10826CK-666;化合物CK-666CK-666
CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.
价 格:¥电议型 号:T10826产 地:中国大陆
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T10825Citrinin;桔霉素NSC 186;NSC 186|||桔霉素
Citrinin is a mycotoxin that causes contamination in the food and is associated with different toxic effects. Citrinin also possesses a broad spectrum of bioactivities, including antifungal, antibacterial, and potential anticancer and neuroprotective effects in vitro.
价 格:¥电议型 号:T10825产 地:中国大陆
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T10824cis-Urocanic acid;顺式-尿刊酸cis-UCA|||(Z)-Imidazole-4-acrylic acid|||(Z)-Urocanic acid|||(E)-Urocanic ac
cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
价 格:¥电议型 号:T10824产 地:中国大陆
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T10823trans-Pralsetinib化合物 T10823cis-Pralsetinib|||cis-BLU-667
trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).
价 格:¥电议型 号:T10823产 地:中国大陆
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T10822Cirsimarin;滨蓟黄甙Cirsitakaoside;Cirsitakaoside
Cirsimarin (Cirsitakaoside) is a flavonoid isolated from Microtea debilis. It shows a potent antilipogenic effect and decreases adipose tissue deposition in mice. Cirsimarin has antagonist activity on the adenosine A1 receptor and inhibitory effect on phosphodiesterase.
价 格:¥电议型 号:T10822产 地:中国大陆
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T10821Cirsiliol;化合物 T10821Cirsiliol
Cirsiliol is a selective inhibitor of 5-lipoxygenase and a competitive low-affinity ligand of benzodiazepine receptors.
价 格:¥电议型 号:T10821产 地:中国大陆
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T10820L1Ciraparantag acetate;化合物Ciraparantag acetateCiraparantag acetate(1438492-26-2 Free base);Ciraparanta
Ciraparantag acetate, an anticoagulant reversal agent, is a small molecule specifically designed to bind noncovalently by charge-charge interaction to unfractionated heparin and low-molecular-weight heparin.?It shows binding characteristics that are similar to those of direct oral anticoagulants (DOACs).
价 格:¥电议型 号:T10820L1产 地:中国大陆
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T10820LCiraparantag TFA;化合物 T10820LPER977 TFA;PER977 TFA
Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
价 格:¥电议型 号:T10820L产 地:中国大陆
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T10820Ciraparantag化合物 T10820PER977
Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
价 格:¥电议型 号:T10820产 地:中国大陆
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T1082Benzyl isothiocyanate苄基异硫氰酸酯Benzoylthiocarbimide|||苄基异硫氰酸酯|||异硫氰酸苯甲酯|||Isothiocyanic Acid Benzoyl Es
Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.
价 格:¥电议型 号:T1082产 地:中国大陆
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T10819Cipropride S enantiomer;环丙必利 (S 异构体)Cipropride S enantiomer
Cipropride S enantiomer is the S enantiomer of cipropride which is an antiemetic drug.
价 格:¥电议型 号:T10819产 地:中国大陆
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T10818Ciprofibrate D6;化合物 T10818Ciprofibrate D6
Ciprofibrate D6 is a deuterium-labeled Ciprofibrate. Ciprofibrate is an agonist of peroxisome proliferator-activated receptor.
价 格:¥电议型 号:T10818产 地:中国大陆
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T10817Cipemastat;化合物 T10817Ro 32-3555;Ro 32-3555
Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).
价 格:¥电议型 号:T10817产 地:中国大陆