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T18523PC Methyltetrazine-PEG4-NHS carbonate ester；化合物 T18523PC Methyltetrazine-PEG4-NHS carbonate ester
PC Methyltetrazine-PEG4-NHS carbonate ester is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
价 格：￥电议型 号：T18523产 地：中国大陆
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T18522PC Mal-NHS carbonate ester；化合物 T18522PC Mal-NHS carbonate ester
PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonate ester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its imp
价 格：￥电议型 号：T18522产 地：中国大陆
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T18521PC DBCO-PEG3-biotin；化合物 T18521PC DBCO-PEG3-biotin
PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker, specifically designed for antibody-drug conjugate (ADC) synthesis, with a cleavable moiety consisting of a dibenzocyclooctyne (DBCO) group and a biotin molecule. This linker provides a platform for the efficient attachment of drugs to antibodies, facilitating the targeted delivery and controlled release of therapeutic agents in ADCs[1].
价 格：￥电议型 号：T18521产 地：中国大陆
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T18520PC-Biotin-PEG4-PEG3-azide；化合物 T18520PC-Biotin-PEG4-PEG3-azide
PC-Biotin-PEG4-PEG3-azide is a cleavable 7-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed for the synthesis of ADCs [1].
价 格：￥电议型 号：T18520产 地：中国大陆
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T18519PC-Biotin-PEG4-NHS carbonate；化合物 T18519PC-Biotin-PEG4-NHS carbonate
PC-Biotin-PEG4-NHS carbonate is a polyethylene glycol (PEG) derived linker employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T18519产 地：中国大陆
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T18518PC Biotin-PEG3-NHS ester；化合物 T18518PC Biotin-PEG3-NHS ester
PC Biotin-PEG3-NHS ester is a cleavable ADC linker comprising three PEG units. This linker is specifically designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18518产 地：中国大陆
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T18517PC Azido-PEG11-NHS carbonate ester；化合物 T18517PC Azido-PEG11-NHS carbonate ester
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].
价 格：￥电议型 号：T18517产 地：中国大陆
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T18516PC Alkyne-PEG4-NHS ester；化合物 T18516PC Alkyne-PEG4-NHS ester
PC Alkyne-PEG4-NHS ester is a cleavable 4-unit PEG linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18516产 地：中国大陆
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T1835Ibrutinib；伊布替尼PCI-32765；伊布替尼|||依鲁替尼|||PCI-32765
Ibrutinib (PCI-32765) is a Bruton´s tyrosine kinase (BTK) inhibitor (IC50=0.5 nM) with irreversible and selective properties. Ibrutinib blocks BTK to inhibit the proliferation and survival of B cells, and possesses antitumor activity, which can be used for the treatment of chronic lymphocytic leukemia, among others.
价 格：￥电议型 号：T1835产 地：中国大陆
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T18105m-PEG-NPC (MW 20000)；化合物 T18105m-PEG-NPC (MW 20000)
m-PEG-NPC (MW 20000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18105产 地：中国大陆
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T17927(S,R,S)-AHPC TFA；化合物(S,R,S)-AHPC TFAVH032-NH2 TFA|||VHL ligand 1 TFA；VH032-NH2 TFA|||VHL ligand 1 TF
(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to create PROTACs (e.g., GMB-475), which effectively induce the degradation of BCR-ABL1, demonstrated by an IC50 of 1.11 μM in Ba/F3 cells.
价 格：￥电议型 号：T17927产 地：中国大陆
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T17926(S,R,S)-AHPC-PEG6-C4-Cl；化合物 T17926VHL Ligand-Linker Conjugates 10|||E3 ligase Ligand-Linker Conjugat
(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
价 格：￥电议型 号：T17926产 地：中国大陆
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T17925(S,R,S)-AHPC-PEG2-NH2化合物(S,R,S)-AHPC-PEG2-NH2VH032-PEG2-NH2|||VHL Ligand-Linker Conjugates 3|||E3 li
(S,R,S)-AHPC-PEG2-NH2 (VHL Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
价 格：￥电议型 号：T17925产 地：中国大陆
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T17924(S,R,S)-AHPC-PEG2-NH2 hydrochloride；化合物(S,R,S)-AHPC-PEG2-NH2 盐酸盐VH032-PEG2-NH2 hydrochloride|||VHL L
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTAC.
价 格：￥电议型 号：T17924产 地：中国大陆
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T17923(S,R,S)-AHPC-PEG3-NH2；化合物 T17923E3 ligase Ligand-Linker Conjugates 5 Free Base|||VH032-PEG3-NH2|||VH
(S,R,S)-AHPC-PEG3-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, incorporating the (S,R,S)-AHPC VHL ligand and a 3-unit PEG linker, which are utilized in PROTAC technology.
价 格：￥电议型 号：T17923产 地：中国大陆
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T17922(S,R,S)-AHPC-PEG3-NH2 hydrochloride；化合物T17922VHL Ligand-Linker Conjugates 1 hydrochloride|||E3 ligas
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC-based VHL ligand and 3-unit PEG linker.
价 格：￥电议型 号：T17922产 地：中国大陆
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T17921(S,R,S)-AHPC-PEG4-N3；化合物T17921VH032-PEG4-N3|||VHL Ligand-Linker Conjugates 5|||E3 ligase Ligand-Link
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology.
价 格：￥电议型 号：T17921产 地：中国大陆
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T17920(S,R,S)-AHPC-PEG1-N3；化合物(S,R,S)-AHPC-PEG1-N3VHL Ligand-Linker Conjugates 9|||VH032-PEG1-N3|||E3 liga
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG1-N3 incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.
价 格：￥电议型 号：T17920产 地：中国大陆
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T17913(S,R,S)-AHPC-PEG2-N3化合物T17913VHL Ligand-Linker Conjugates 6|||VH032-PEG2-N3|||E3 ligase Ligand-Linke
(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate containing a (S,R,S)-AHPC based VHL ligand and 2 unit PEG linker.
价 格：￥电议型 号：T17913产 地：中国大陆
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T17912(S,R,S)-AHPC-(C3-?PEG)?2-?C6-?Cl；化合物 T17912VHL Ligand-Linker Conjugates 11|||E3 ligase Ligand-Linker
(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
价 格：￥电议型 号：T17912产 地：中国大陆
