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T38510ABT-072 potassium trihydrate;ABT-072 potassium trihydrateABT-072 potassium trihydrate
ABT-072, also known as potassium trihydrate, is a highly effective non-nucleoside inhibitor of the HCV NS5B polymerase, administered orally. This compound exhibits potent activity against HCV GT1a (with an EC50 of 1 nM) and HCV GT1b (with an EC50 of 0.3 nM).
价 格:¥电议型 号:T38510产 地:中国大陆
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T38472Phosphoribosyl pyrophosphate pentasodium磷酸核糖焦磷酸PRPPpentasodium|||磷酸核糖焦磷酸
Phosphoribosyl pyrophosphate (PRPP) pentasodium is a vital metabolite essential for the biosynthesis of purine and pyrimidine nucleotides, as well as the amino acids histidine and tryptophan. It also acts as a precursor for the important cofactors NAD and NADP.
价 格:¥电议型 号:T38472产 地:中国大陆
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T38393Ipatasertib-NH2 dihydrochloride;Ipatasertib-NH2 dihydrochlorideRG7440-NH2 dihydrochloride|||Ipataser
Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquitin ligase.
价 格:¥电议型 号:T38393产 地:中国大陆
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T38350TAS 205;TAS 205TAS 205
TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS; IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 μM, as well as over enzyme and receptor panels at 10 μM. TAS 205 inhibits production of prostaglandin D2induced by A23187 in KU812 human and RBL-2H3 rat basophils with IC50values of 78.3 and 181.3 nM, respectively. It inhibits ovalbumin-induced nasal lavage fluid eosinophil infiltration and late-phase nasal obstruction in an ovalbumin-sens
价 格:¥电议型 号:T38350产 地:中国大陆
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T37915Monodes(N-carboxymethyl)valine Daclatasvir;Monodes(N-carboxymethyl)valine DaclatasvirMonodes(N-carbo
Monodes(N-carboxymethyl)valine Daclatasvir, also known as Daclatasvir Impurity A, is the principal degradation product of Daclatasvir.Daclatasvir is a potent inhibitor of the HCV NS5A protein[1].
价 格:¥电议型 号:T37915产 地:中国大陆
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T37764Cal Green? 1 (potassium salt);Cal Green? 1 (potassium salt)Cal Green? 1 (potassium salt)
Cal Green 1 is a cell-impermeant fluorescent calcium indicator that is characterized by high quantum yield and low phototoxicity. Its peak excitation and emission wavelengths (506 and 531 nm, respectively) are comparable to standard fluorescein dyes, making Cal Green 1 appropriate for fluorescent microscopy. Cal Green 1 is ~5-fold brighter than fluo-3 at saturating calcium levels.
价 格:¥电议型 号:T37764产 地:中国大陆
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T37761Fura-FF (potassium salt);Fura-FF (potassium salt)Fura-FF (potassium salt)
Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation.[1] Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively).[1],[2]However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presen
价 格:¥电议型 号:T37761产 地:中国大陆
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T37759Fura-2 (potassium salt);Fura-2 (potassium salt)Fura-2 (potassium salt)
Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells. [1] It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells.
价 格:¥电议型 号:T37759产 地:中国大陆
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T373657-hydroxy Coumarin sulfate (potassium salt);7-hydroxy Coumarin sulfate (potassium salt)7-hydroxy Cou
7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.
价 格:¥电议型 号:T37365产 地:中国大陆
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T37324Sucrose hexasulfate (potassium salt);Sucrose hexasulfate (potassium salt)Sucrose hexasulfate (potass
Sucralfate is a gastrointestinal protectant that includes sucrose octasulfate . Sucralfate protects gastric epithelial cells against acid- and pepsin-induced damage. Sucrose hexasulfate is a polysulfated disaccharide that is used as a reference standard for sucralfate.
价 格:¥电议型 号:T37324产 地:中国大陆
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T37318Fluo-3FF (potassium salt);Fluo-3FF (potassium salt)Fluo-3FF (potassium salt)
Fluo-3FF is a fluorescent calcium indicator. It is a di-fluorinated analog of Fluo-3 that displays about a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 μM, respectively). Low affinity calcium indicators are particularly useful for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations. Fluo-3FF has excitation/emission maxima of approximately 506 and 526 nm, respectively.
价 格:¥电议型 号:T37318产 地:中国大陆
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T37316Fluo-3 (potassium salt);Fluo-3 (potassium salt)Fluo-3 (potassium salt)
Fluo-3 (potassium salt) is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
价 格:¥电议型 号:T37316产 地:中国大陆
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T37310Diadenosine pentaphosphate pentasodium;Diadenosine pentaphosphate pentasodiumDiadenosine pentaphosph
Diadenosine pentaphosphate pentasodium, an endogenous vasoactive purine dinucleotide isolated from thrombocytes, serves as a key component of secretory vesicles in platelets, chromaffin cells, Torpedo synaptic terminals, and brain synaptosomes. This compound, along with other diadenosine polyphosphates (ApnA, n=2-7), plays a crucial role in physiological processes[1][2].
价 格:¥电议型 号:T37310产 地:中国大陆
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T37095Quin-2 (potassium salt);Quin-2 (potassium salt)Quin-2 (potassium salt)
Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium). It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 an
价 格:¥电议型 号:T37095产 地:中国大陆
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T37090Indo-1 (potassium salt);Indo-1 (potassium salt)Indo-1 (potassium salt)
Indo-1 (potassium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when Indo-1 (potassium salt) binds calcium. Indo-1 (potassium salt) is prone to photobleaching, which limits its usefulness in methods involving microscopy.
价 格:¥电议型 号:T37090产 地:中国大陆
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T37004Estradiol 3-sulfate 17β-Glucuronide (potassium salt);Estradiol 3-sulfate 17β-Glucuronide (potassium
Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com
价 格:¥电议型 号:T37004产 地:中国大陆
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T36848Combretastatin A-1;康普瑞汀A-1Combretastatin A1;Combretastatin A1
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and can be used to study hepatocellular carcinoma.
价 格:¥电议型 号:T36848产 地:中国大陆
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T36714Sucrose octasulfate (potassium salt);Sucrose octasulfate (potassium salt)Sucrose octasulfate (potass
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 μM) and inhibit its catalytic activity (IC50 = 4.5 μM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by pr
价 格:¥电议型 号:T36714产 地:中国大陆
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T36695TAS-103;TAS-103 (BMS-247615)TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research.
价 格:¥电议型 号:T36695产 地:中国大陆
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T3667Kalii Dehydrographolidi Succinas;穿琥宁Ddhads|||Dehydroandrographolide Succinate Potasium Salt;Ddhads||
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.
价 格:¥电议型 号:T3667产 地:中国大陆