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已选条件
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T17420Amino-PEG24-acid;化合物 T17420Amino-PEG24-acid
Amino-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17420产 地:中国大陆
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T17417Amino-PEG20-Boc;化合物 T17417Amino-PEG20-Boc
Amino-PEG20-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17417产 地:中国大陆
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T17416Amino-PEG20-acid;化合物 T17416Amino-PEG20-acid
Amino-PEG20-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17416产 地:中国大陆
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T17398Amine-PEG-thiol (MW 2000);化合物 T17398Amine-PEG-thiol (MW 2000)
Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker employed in PROTAC synthesis[1].
价 格:¥电议型 号:T17398产 地:中国大陆
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T17397Amine-PEG-CH2COOH (MW 2000);化合物Amine-PEG-CH2COOH (MW 2000)Amine-PEG-CH2COOH (MW 5000);Amine-PEG-CH2C
Amine-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17397产 地:中国大陆
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T17391Amine-PEG-amine (MW 20000);化合物 T17391Amine-PEG-amine (MW 20000)
Amine-PEG-amine (MW 20000) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs.
价 格:¥电议型 号:T17391产 地:中国大陆
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T17390Amine-PEG-amine (MW 2000);化合物 T17390Amine-PEG-amine (MW 2000)
Amine-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative that functions as a linker for PROTAC synthesis. PROTACs are small molecules used for targeted protein degradation [1].
价 格:¥电议型 号:T17390产 地:中国大陆
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T17359Acrylate-PEG-NH2 (MW 2000);化合物 T17359Acrylate-PEG-NH2 (MW 2000)
Acrylate-PEG-NH2 (MW 2000) is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTACs [1].
价 格:¥电议型 号:T17359产 地:中国大陆
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T173201,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane;化合物 T173201-3-bis-carboxyethoxy-2-2-bis-carboxy
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a polyethylene glycol (PEG)-based linker compound suitable for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17320产 地:中国大陆
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T17277YS-201;化合物 T17277YS-201
YS-201 is an antagonist of dihydropyridine-type calcium channel.
价 格:¥电议型 号:T17277产 地:中国大陆
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T17220Vecabrutinib;维卡布鲁替尼SNS-062;SNS-062
Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.
价 格:¥电议型 号:T17220产 地:中国大陆
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T17211Vafidemstat;化合物 VafidemstatORY-2001;ORY-2001
Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neurological diseases.
价 格:¥电议型 号:T17211产 地:中国大陆
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T1720LAmfenac;化合物 T1720LNSC309467|||NSC-309467|||NSC 309467;NSC309467|||NSC-309467|||NSC 309467
Amfenac promotes apoptosis in ARPE-19 cell culture.
价 格:¥电议型 号:T1720L产 地:中国大陆
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T17209UVI 3003;化合物UVI 3003UVI 3003
UVI 3003 is a highly selective antagonist of the retinoid X receptor. UVI 3003 inhibits Xenopus and human RXRα in Cos7 cells (IC50s: 0.22 and 0.24 μM, respectively).
价 格:¥电议型 号:T17209产 地:中国大陆
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T17208USL311;化合物USL311USL311
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
价 格:¥电议型 号:T17208产 地:中国大陆
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T17206UPGL00004;化合物UPGL00004UPGL00004
UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast cancer cell lines.
价 格:¥电议型 号:T17206产 地:中国大陆
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T17205UNC2541;化合物UNC2541UNC2541
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
价 格:¥电议型 号:T17205产 地:中国大陆
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T17204UNC0321;化合物UNC0321UNC0321
UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays.
价 格:¥电议型 号:T17204产 地:中国大陆
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T17203UNC0224;化合物UNC0224UNC0224
UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.
价 格:¥电议型 号:T17203产 地:中国大陆
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T17202Ulimorelin;化合物 T17202TZP-101;TZP-101
Ulimorelin is a ghrelin receptor agonist (EC50: 29 nM and a Ki of 16 nM). Ulimorelin is a prokinetic agent and causes vasorelaxation through competitive antagonist action at α1-adrenoceptors.
价 格:¥电议型 号:T17202产 地:中国大陆