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T17911(S,R,S)-AHPC-C6-PEG3-C4-Cl;化合物 T17911VH032-C6-PEG3-C4-Cl|||VHL Ligand-Linker Conjugates 12|||E3 liga
(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
价 格:¥电议型 号:T17911产 地:中国大陆
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T17910(S,R,S)-AHPC-PEG2-C4-Cl;化合物 T17910E3 ligase Ligand-Linker Conjugates 10|||VHL Ligand-Linker Conjugat
(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
价 格:¥电议型 号:T17910产 地:中国大陆
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T17909(S,R,S)-AHPC-PEG3-N3;化合物(S,R,S)-AHPC-PEG3-N3VHL Ligand-Linker Conjugates 8|||VH032-PEG3-N3|||E3 liga
(S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T17909产 地:中国大陆
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T17905(S,R,S)-AHPC-PEG1-OTs;化合物 T17905VH032-PEG1-OTs|||VHL Ligand-Linker Conjugates 2|||E3 ligase Ligand-L
(S,R,S)-AHPC-PEG1-OTs is a chemically synthesized conjugate, functioning as an ligase ligand-linker for E3 ligase. It incorporates the VHL ligand derived from (S,R,S)-AHPC and a 1-unit PEG linker. This synthesized compound is commonly employed in PROTAC technology.
价 格:¥电议型 号:T17905产 地:中国大陆
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T17881(S,R,S)-AHPC-C10-NH2;化合物(S,R,S)-AHPC-C10-NH2VH032-C10-NH2;VH032-C10-NH2
(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.
价 格:¥电议型 号:T17881产 地:中国大陆
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T17586Biotin-PEG4-PC-PEG4-alkyne;化合物 T17586Biotin-PEG4-PC-PEG4-alkyne
Biotin-PEG4-PC-PEG4-alkyne is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17586产 地:中国大陆
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T17237VPC 23019;化合物VPC 23019VPC 23019
VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively). It is also an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).
价 格:¥电议型 号:T17237产 地:中国大陆
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T17229Verubulin化合物 T17229MPC 6827
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.
价 格:¥电议型 号:T17229产 地:中国大陆
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T16572Prasugrel (Maleic acid);马来酸普拉格雷PCR 4099 (Maleic acid);马来酸普拉格雷|||PCR 4099 (Maleic acid)
Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation. Prasugrel Maleic acid is a thienopyridine and prodrug. Prasugrel Maleic acid also inhibits platelet function.
价 格:¥电议型 号:T16572产 地:中国大陆
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T16571Pranidipine;普拉地平OPC-13340;普拉地平|||OPC-13340
Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker. It prolongs acetylcholine-induced relaxation in presence of endothelium as well as nitroglycerin-induced relaxation in absence of endothelium. It also has antihypertensive activity.
价 格:¥电议型 号:T16571产 地:中国大陆
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T16565Ppc-1;化合物 T16565Ppc-1
Ppc-1 is a chemical compound known for its inhibitory effects on the Gram-negative periodontopathogen Porphyromonas gingivalis. It acts as a mitochondrial uncoupler, enhancing mitochondrial oxygen consumption without affecting ATP production. Additionally, Ppc-1 serves as a cell-permeate inhibitor of interleukin-2 (IL-2). This compound exhibits various beneficial activities, including anti-obesity, antibacterial, and anti-inflammatory properties.
价 格:¥电议型 号:T16565产 地:中国大陆
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T16443PCS1055 dihydrochloride;化合物 T16443PCS1055 dihydrochloride
PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, respectively). PCS1055 dihydrochloride inhibits radioligand [3H]-NMS binding to the M4 receptor (Ki: 6.5 nM). PCS1055 dihydrochloride shows >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor.
价 格:¥电议型 号:T16443产 地:中国大陆
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T16442PCO371;化合物PCO3712,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor.
价 格:¥电议型 号:T16442产 地:中国大陆
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T16441PCI-33380;化合物 T16441PCI-33380
PCI-33380 is an irreversible inhibitor of Bruton´s Tyrosine Kinase.
价 格:¥电议型 号:T16441产 地:中国大陆
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T16440Ibrutinib Racemate化合物 T16440PCI-32765 (Racemate)
Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.
价 格:¥电议型 号:T16440产 地:中国大陆
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T16439PC786;化合物 T16439PC786
PC786 shows effective antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM). PC786 is an inhaled respiratory syncytial virus L protein polymerase inhibitor.
价 格:¥电议型 号:T16439产 地:中国大陆
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T16438PC Biotin-PEG3-azide;化合物 T16438PC Biotin-PEG3-azide
PC Biotin-PEG3-azide is a cleavable three-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker, employed in the synthesis of ADCs[1].
价 格:¥电议型 号:T16438产 地:中国大陆
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T16437PC Biotin-PEG3-alkyne;化合物PC Biotin-PEG3-alkynePC Biotin-PEG3-alkyne
PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).
价 格:¥电议型 号:T16437产 地:中国大陆
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T16081MIV-150;化合物 T16081PC 815;PC 815
MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).
价 格:¥电议型 号:T16081产 地:中国大陆
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T1566Aripiprazole;阿立哌唑OPC-14597;阿立哌唑|||OPC-14597
Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A.
价 格:¥电议型 号:T1566产 地:中国大陆