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T135206-Hydroxymelatonin化合物 T135206Hydroxymelatonin|||6 Hydroxymelatonin
6-Hydroxymelatonin is a primary metabolic of Melatonin, which is metabolized by CYP 1A2.
价 格：￥电议型 号：T13520产 地：中国大陆
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T135185α-Pregnane-3β,6α-diol-20-one；化合物5α-Pregnane-3β,6α-diol-20-one5α-Pregnane-3β,6α-diol-20-one
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation.
价 格：￥电议型 号：T13518产 地：中国大陆
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T135003-O-Acetyl-20-Hydroxyecdysone；3-乙酰基-β-蜕皮甾酮3-O-Acetyl-20-Hydroxyecdysone
3-O-Acetyl-20-Hydroxyecdysone, a steroid extracted from the roots of Cyanotis arachnoidea C.B.Clark, is characterized by its unique structural modifications.
价 格：￥电议型 号：T13500产 地：中国大陆
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T13460(+)-Cevimeline hydrochloride hemihydrate；化合物 T13460(+)-AF102B hydrochloride hemihydrate|||(+)-SNI-20
(+)-Cevimeline hydrochloride hemihydrate ((+)-SNI-2011), a potent muscarinic receptor agonist, stands as a promising therapeutic candidate for treating xerostomia in Sjogren´s syndrome. This compound has demonstrated a broad pharmacological profile across various systems including gastrointestinal, urinary, and reproductive, in animal models such as mice, rats, guinea pigs, rabbits, and dogs. Its metabolism was assessed in vitro using rat and dog liver microsomes, revealing that (+)-SNI-20
价 格：￥电议型 号：T13460产 地：中国大陆
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T13438(R,S)-Ivosidenib；化合物 T13438(R,S)-AG-120；(R,S)-AG-120
(R,S)-Ivosidenib is the less active enantiomer of Ivosidenib .
价 格：￥电议型 号：T13438产 地：中国大陆
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T13421(-)-Cevimeline hydrochloride hemihydrate；化合物 T13421(-)-SNI-2011|||(-)-AF102B hydrochloride hemihydra
Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is being explored as a potential treatment for xerostomia in Sjogren´s syndrome, exhibiting an IC50 value indicative of its affinity for mAChR. This compound´s pharmacological effects on the gastrointestinal, urinary, and reproductive systems, alongside its impact on various tissues, were thoroughly examined in species including mice, rats, guinea pigs, rabbits, and dogs. The metabolic breakdown
价 格：￥电议型 号：T13421产 地：中国大陆
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T13412LZM223 hydrochloride (2031177-48-5 free base)；化合物 T13412LZM223 hydrochloride；ZM223 hydrochloride
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
价 格：￥电议型 号：T13412L产 地：中国大陆
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T13367YKL-5-124 TFA (1957203-01-8 free base)；化合物 T13367YKL-5-124 TFA；YKL-5-124 TFA
YKL-5-124 TFA is a potent, selective, irreversible and covalent inhibitor of CDK7 (IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively).
价 格：￥电议型 号：T13367产 地：中国大陆
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T1334320-HEDE；化合物 T13343WIT 002；WIT 002
20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.
价 格：￥电议型 号：T13343产 地：中国大陆
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T13340Win-62005；化合物 T13340Win-62005
Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta).
价 格：￥电议型 号：T13340产 地：中国大陆
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T13333WD2000-012547；化合物 T13333WD2000-012547
WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).
价 格：￥电议型 号：T13333产 地：中国大陆
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T13329LVofopitant dihydrochloride沃弗呲坦盐酸盐GR 205171A|||Vofopitant 2HCl
Vofopitant dihydrochloride (GR 205171A) is an orally available, selective tachykinin NK1 receptor antagonist that inhibits [3H]SP binding to NK1 with pKi values of 9.5 and 10.6, respectively.Vofopitant dihydrochloride is a potential compound for the treatment of pathological vomiting. Vofopitant dihydrochloride is a potential compound for the treatment of pathological vomiting.
价 格：￥电议型 号：T13329L产 地：中国大陆
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T13329Vofopitant；沃弗吡坦GR 205171；GR 205171
Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).
价 格：￥电议型 号：T13329产 地：中国大陆
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T13324VUF11207 fumarate；化合物VUF11207 fumarateVUF11207 fumarate
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
价 格：￥电议型 号：T13324产 地：中国大陆
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T13320VU591 hydrochloride；化合物VU591 hydrochlorideVU591 hydrochloride
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50：0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590
价 格：￥电议型 号：T13320产 地：中国大陆
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T13279LValemetostat；化合物ValemetostatDS-3201；DS-3201
Valemetostat (DS-3201) is a first-in-class EZH1/2 dual inhibitor.
价 格：￥电议型 号：T13279L产 地：中国大陆
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T13279Valemetostat tosylate化合物 T13279DS-3201 tosylate
Valemetostat tosylate is a dual inhibitor of EZH1/2 and used in the research of relapsed/refractory peripheral T-cell lymphoma.
价 格：￥电议型 号：T13279产 地：中国大陆
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T13256UP202-56；化合物 T13256UP202-56
UP202-56 is an adenosinergic agonist and is an adenosine analog.
价 格：￥电议型 号：T13256产 地：中国大陆
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T13253Umibecestat；化合物UmibecestatCNP520；CNP520
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer´s disease.
价 格：￥电议型 号：T13253产 地：中国大陆
